PTCH2

864319207ENSG00000117425ENSMUSG00000028681Q9Y6C5O35595NM_003738NM_001166292NM_008958NM_001312903NP_001159764NP_003729NP_001299832NP_032984Patched 2 is a protein that in humans is encoded by the PTCH2 gene. Patched 2 is a protein that in humans is encoded by the PTCH2 gene. This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. This article incorporates text from the United States National Library of Medicine, which is in the public domain.