Nerve growth factor receptor

Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Two classes of neurotrophic factor receptors are the p75 and the 'Trk' families of Tyrosine kinases receptors. TrkA mediates its actions by causing the addition of phosphate molecules on certain tyrosines in the cell, activating cellular signaling. There are other related Trk receptors (TrkB and TrkC), and there are other neurotrophic factors structurally related to NGF (BDNF, NT-3, and NT-4) The other NGF receptor, the LNGFR, (for Low affinity nerve growth factor receptor, commonly known as 'p75', plays a less clear role.