A dacrocyte (or dacryocyte) is a type of poikilocyte that is shaped like a teardrop (a 'teardrop cell'). A marked increase of dacrocytes is known as dacrocytosis.These tear drop cells are found primarily in diseases with bone marrow fibrosis, such as: primary myelofibrosis, myelodysplastic syndromes during the late course of the disease, rare form of acute leukemias and myelophtisis caused by metastatic cancers. Rare causes are myelofibrosis associated with post-irradiation, toxins, autoimmune diseases, metabolic conditions, inborn hemolytic anemias, iron-deficiency anemia or β-thalassemia. A dacrocyte (or dacryocyte) is a type of poikilocyte that is shaped like a teardrop (a 'teardrop cell'). A marked increase of dacrocytes is known as dacrocytosis.These tear drop cells are found primarily in diseases with bone marrow fibrosis, such as: primary myelofibrosis, myelodysplastic syndromes during the late course of the disease, rare form of acute leukemias and myelophtisis caused by metastatic cancers. Rare causes are myelofibrosis associated with post-irradiation, toxins, autoimmune diseases, metabolic conditions, inborn hemolytic anemias, iron-deficiency anemia or β-thalassemia. From Ancient Greek, δάκρυον: a teardrop