RSPO3

8487072780ENSG00000146374ENSMUSG00000019880Q9BXY4Q2TJ95NM_032784NM_028351NP_116173NP_082627R-spondin-3 is a protein that in humans is encoded by the RSPO3 gene. R-spondin-3 is a protein that in humans is encoded by the RSPO3 gene. This gene encodes a member of the thrombospondin type 1 repeat supergene family. In addition, the protein contains a furin-like cysteine-rich region. Furin-like repeat domains have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases. During embryonic development, RSPO3 is expressed in the tail bud and the posterior presomitic mesoderm of the embryo. In tissue engineering, R-spondin 3 has been used to differentiate pluripotent stem cells into paraxial mesoderm progenitors