Sulfinamide

Sulfinamide is a functional group in organosulfur chemistry with the formula RS(O)NR'2 (R and R' = organic substituent). With a sulfur-oxygen double bond as well as S-C and S-N single bonds, the compounds are chiral. Sulfinamides are amides of sulfinic acid (RS(O)OH). Sulfinamide is a functional group in organosulfur chemistry with the formula RS(O)NR'2 (R and R' = organic substituent). With a sulfur-oxygen double bond as well as S-C and S-N single bonds, the compounds are chiral. Sulfinamides are amides of sulfinic acid (RS(O)OH). Tert-Butanesulfinamide, p-toluenesulfinamide, and 2,4,6-trimethylbenzenesulfinamide have been obtained in optically pure form. They are used in asymmetric synthesis. Sulfinamides arise in nature by the addition of thiols to nitroxyl: