GLUD2

2747n/aENSG00000182890n/aP49448n/aNM_012084n/aNP_036216n/aGlutamate dehydrogenase 2, mitochondrial, also known as GDH 2, is an enzyme that in humans is encoded by the GLUD2 gene. This dehydrogenase is one of the family of glutamate dehydrogenases that are ubiquitous in life.1hwx: CRYSTAL STRUCTURE OF BOVINE LIVER GLUTAMATE DEHYDROGENASE COMPLEXED WITH GTP, NADH, AND L-GLUTAMIC ACID1hwy: BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE1hwz: BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NADPH, GLUTAMATE, AND GTP1l1f: Structure of human glutamate dehydrogenase-apo form1nqt: Crystal structure of bovine Glutamate dehydrogenase-ADP complex1nr7: Crystal structure of apo bovine glutamate dehydrogenase1nr1: Crystal structure of the R463A mutant of human Glutamate dehydrogenase Glutamate dehydrogenase 2, mitochondrial, also known as GDH 2, is an enzyme that in humans is encoded by the GLUD2 gene. This dehydrogenase is one of the family of glutamate dehydrogenases that are ubiquitous in life. Glutamate dehydrogenase 2 is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate.