Keratitis–ichthyosis–deafness syndrome (also known as 'Ichthyosiform erythroderma, corneal involvement, and deafness,' and 'KID syndrome,') presents at birth/infancy and is characterized by progressive corneal opacification, either mild generalized hyperkeratosis or discrete erythematous plaques, and neurosensory deafness.:483,513:565 Keratitis–ichthyosis–deafness syndrome (also known as 'Ichthyosiform erythroderma, corneal involvement, and deafness,' and 'KID syndrome,') presents at birth/infancy and is characterized by progressive corneal opacification, either mild generalized hyperkeratosis or discrete erythematous plaques, and neurosensory deafness.:483,513:565 It is caused by a mutation in connexin 26.