Exsanguination is the loss of blood to a degree sufficient to cause death. One does not have to lose all of one's blood to cause death. Depending upon the age, health, and fitness level of the individual, people can die from losing half to two-thirds of their blood; a loss of roughly one-third of the blood volume is considered very serious. Even a single deep cut can warrant suturing and hospitalization, especially if trauma, a vein or artery, or another comorbidity is involved. It is most commonly known as 'bleeding to death' or colloquially as 'bleeding out'. The word itself originates from Latin: ex ('out of') and sanguis ('blood'). Exsanguination is used as a method of slaughter. Before the fatal incision is made, the animal may be rendered insensible to pain by various methods, including captive bolt, electricity or chemical. Without prior sedation, stunning or anesthetic, this method of slaughter causes a high degree of anxiety, although other religiously funded studies contradict these findings. The captive bolt is placed against the skull of the animal, and penetrates to cause tissue destruction in the brain, incapacitating the animal so that the procedure may take place. Electricity is used mostly to incapacitate swine, poultry and domestic sheep, whereas a chemical is used for injured livestock. Continued pumping operation of the heart during exsanguination increases the rate of depletion, and thus hastens death, by raising the fluid pressure of the blood. Because the heart operates like a positive displacement pump, reduction of blood volume will not affect efficiency of cardiac output—deprivation of blood to the heart does gradually result in diminished function, but concurrently with similar death of other parts in the body. Quickly after the animal is incapacitated it is hung upside down by its hind limbs and an extremely sharp knife, in an orientation parallel to the ground, is fully inserted through the skin just behind the point of the jaw and below the neck bones. From this position, the knife is drawn forward away from the spine to sever the jugular veins, carotid arteries, and trachea. Properly performed, blood will flow freely and death will occur within seconds. Sheep and swine will reach brain death in under 10 seconds; however, larger animals, notably cattle may take up to 40 seconds to reach brain death. This period may extend to a couple of minutes if complications, such as arterial occlusion, occur. However, the animal's inverted position allows blood to flow more precipitously and thus makes an animal regaining consciousness before it is fully exsanguinated highly unlikely. In any case, animal welfare advisory councils clearly emphasize that the time from incapacitation to start of exsanguination should be prompt; recommending a time under 15 seconds.