Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID). It is a metabolite of phenylbutazone. Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID). It is a metabolite of phenylbutazone. It was withdrawn from markets worldwide in mid-1980s due to bone marrow suppression and risk for Stevens–Johnson syndrome. The word oxyphenbutazone is the theoretically highest scoring word under American rules for Scrabble.