Pityriasis lichenoides et varioliformis acuta (PLEVA) is a disease of the immune system. It is the more severe version of pityriasis lichenoides chronica. The disease is characterized by rashes and small lesions on the skin. The disease is more common in males and usually occurs in young adulthood, although it has been seen in every age group and every race. It is possible for the disease to go into remission for short periods of time or forever. Pityriasis lichenoides et varioliformis acuta (PLEVA) is a disease of the immune system. It is the more severe version of pityriasis lichenoides chronica. The disease is characterized by rashes and small lesions on the skin. The disease is more common in males and usually occurs in young adulthood, although it has been seen in every age group and every race. It is possible for the disease to go into remission for short periods of time or forever. There is no known cause of this disease; There is some evidence associating it with Parvovirus B19. It is commonly misdiagnosed as chickenpox or rosacea. Pleva is also often misidentified as a form of staph. The most accurate way to diagnose it is by biopsy. This disease has not been known to be life-threatening. However, there may be mutations of the disease that can cause ulcers on the exterior. It is not contagious and currently there is no cure for the disease, although the lesions can be treated with phototherapy as well as antibiotics, including erythromycin, azithromycin and tetracycline.