Located in the caudal pons and upper medulla oblongata, the nucleus prepositus (also nucleus prepositus hypoglossi) is part of the horizontal gaze holding system. It functions as a neural integrator. Located in the caudal pons and upper medulla oblongata, the nucleus prepositus (also nucleus prepositus hypoglossi) is part of the horizontal gaze holding system. It functions as a neural integrator.