Triazolopyridine is a class of antidepressants chemically and pharmacologically unrelated to other similarly performing antidepressants; clinical effectiveness appears pharmacologically similar to other tricyclic antidepressants, although it seems to have less anticholinergic effects. Triazolopyridine is a class of antidepressants chemically and pharmacologically unrelated to other similarly performing antidepressants; clinical effectiveness appears pharmacologically similar to other tricyclic antidepressants, although it seems to have less anticholinergic effects.