Amnioinfusion is a method in which isotonic fluid is instilled into the amniotic sac. Amnioinfusion is a method in which isotonic fluid is instilled into the amniotic sac. It is primarily used as a treatment in order to correct fetal heart rate changes caused by umbilical cord compression, indicated by variable decelerations seen on cardiotocography. In severe cases of oligohydramnios, amnioinfusion may be performed prophylactically to prevent umbilical cord compression. It has also been used to reduce the risk of meconium aspiration syndrome, though evidence of benefit is mixed. The UK National Institute of Health and Clinical Excellence (NICE) Guidelines recommend against the use of amnioinfusion in women with meconium stained amniotic fluid (MSAF). Complications of amnioinfusion may include chorioamnionitis, umbilical cord prolapse, premature rupture of membranes, preterm labor, and prolongation of labor. . There are case reports of maternal amniotic fluid embolism, but a clear causal relationship has not been demonstrated. It is recommended that amnioinfusion be performed at centers specializing in fetal medicine and within the context of a multidisciplinary team.