Endosialin

5712470445ENSG00000174807ENSMUSG00000056481Q9HCU0Q91V98NM_020404NM_054042NP_065137NP_473383Endosialin is a protein that in humans is encoded by the CD248 gene. Endosialin is a protein that in humans is encoded by the CD248 gene. Endosialin is a member of the “Group XIV”, a novel family of C-type lectin transmembrane receptors which play a role not only in cell–cell adhesion processes but also in host defence. This family comprise two other members, CD93 and Thrombomodulin which are better characterized. The function of endosialin remains elusive, but its expression has been associated with angiogenesis in the embryo and uterus and in tumor development and growth.