Clinical pharmacologists usually have a rigorous medical and scientific training that enables them to evaluate evidence and produce new data through well-designed studies. Clinical pharmacologists must have access to enough outpatients for clinical care, teaching and education, and research as well as be supervised by medical specialists. Their responsibilities to patients include, but are not limited to, analyzing adverse drug effects, therapeutics, and toxicology including reproductive toxicology, cardiovascular risks, perioperative drug management and psychopharmacology. Clinical pharmacology also connects the gap between medical practice and laboratory science. The main objective is to promote the safety of prescription, maximize the drug effects and minimize the side effects. In this aspect, there can be an association with pharmacists skilled in areas of drug information, medication safety and other aspects of pharmacy practice related to clinical pharmacology. In fact, in countries such as USA, Netherlands, and France, pharmacists can be trained to become clinical pharmacists, to improve optimal drug therapy with clinical pharmacology related knowledge.