Twinrix is a vaccine against hepatitis A and hepatitis B, manufactured by GlaxoSmithKline. The full generic name is hepatitis A (inactivated) and hepatitis B (rDNA) (HAB) vaccine (adsorbed). Twinrix is administered over three doses. Twinrix is a vaccine against hepatitis A and hepatitis B, manufactured by GlaxoSmithKline. The full generic name is hepatitis A (inactivated) and hepatitis B (rDNA) (HAB) vaccine (adsorbed). Twinrix is administered over three doses. The name was created because it is a mixture of two earlier vaccines — Havrix, an inactivated-virus Hepatitis A vaccine, and Engerix-B, a recombinant Hepatitis B vaccine. Twinrix, Havrix and Engerix-B are registered trademarks of GlaxoSmithKline. Twinrix first entered the market in early 1997.