GABRA6

255914399ENSG00000145863ENSMUSG00000020428Q16445P16305NM_000811NM_001099641NM_008068NM_001359049NP_000802NP_001093111NP_032094NP_001345978Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene. Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. One study has found a genetic variant in the gene to be associated with the personality trait neuroticism. This article incorporates text from the United States National Library of Medicine, which is in the public domain.