In computer architecture, cycles per instruction (aka clock cycles per instruction, clocks per instruction, or CPI) is one aspect of a processor's performance: the average number of clock cycles per instruction for a program or program fragment. It is the multiplicative inverse of instructions per cycle. In computer architecture, cycles per instruction (aka clock cycles per instruction, clocks per instruction, or CPI) is one aspect of a processor's performance: the average number of clock cycles per instruction for a program or program fragment. It is the multiplicative inverse of instructions per cycle.