PDSS2

5710771365ENSG00000164494ENSMUSG00000038240Q86YH6Q33DR3NM_020381NM_001168289NM_027772NP_065114NP_001161761NP_082048Decaprenyl-diphosphate synthase subunit 2 (PDSS2) is a protein that in humans is encoded by the PDSS2 gene. Decaprenyl-diphosphate synthase subunit 2 (PDSS2) is a protein that in humans is encoded by the PDSS2 gene. The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. It may be associated with Coenzyme Q10 deficiency. This article incorporates text from the United States National Library of Medicine, which is in the public domain.