PRKD2

2COA, 3BGM, 4NNX, 4NNY25865101540ENSG00000105287ENSMUSG00000041187Q9BZL6Q8BZ03NM_001079880NM_001079881NM_001079882NM_016457NM_001252458NM_178900NP_001073349NP_001073350NP_001073351NP_057541NP_001239387NP_849231Serine/threonine-protein kinase D2 or PKD2 is an enzyme that in humans is encoded by the PRKD2 gene.2coa: Solution structure of the PH domain of protein kinase C, D2 type from human Serine/threonine-protein kinase D2 or PKD2 is an enzyme that in humans is encoded by the PRKD2 gene. The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases, a subfamily of protein kinase c. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.