Tricaine mesylate

Tricaine mesylate (Tricaine methanesulfonate, TMS, MS-222), is white powder used for anesthesia, sedation, or euthanasia of fish. TMS is the only anesthetic licensed in the United States for fin fish that are intended for human consumption.The drug can have selective toxicity for poikilotherms due to their lower rate of metabolism in the liver. Tricaine mesylate (Tricaine methanesulfonate, TMS, MS-222), is white powder used for anesthesia, sedation, or euthanasia of fish. TMS is the only anesthetic licensed in the United States for fin fish that are intended for human consumption.The drug can have selective toxicity for poikilotherms due to their lower rate of metabolism in the liver. TMS is a muscle relaxant that operates by preventing action potentials. By blocking action potentials, no signals can be exchanged between the brain and the extremities. There will be no sensory input or muscle contractions which would have been caused by action potential, which includes most muscles.