Performance evaluation which based on Analytic Hierarchy Process (AHP) and Fuzzy Comprehensive Evaluation is a progress to verify architecture engineering construction's efficiency and equity and economy.Under this method, according to fundamental principles of fuzzy mathematics and the evaluation criterion which we already have, the valuator who have to consider a variety of factors which can affect project performance should organize professors give each factor a score to analyze how about the architecture engineering construction.This paper discussed the basic principle and steps of the method and have evaluated the architecture engineering construction performance successfully.Therefore, this method provides a more accurate way of evaluation about architecture engineering construction Performance evaluation, which is helpful to reduce the influence of subject consciousness when it times to evaluate project performance.In addition, the paper gives the feasibility and limitations of this method in practical applications.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Oncolytic viruses have been considered promising cancer immunotherapies. However, oncovirotherapy agents impart durable responses in only a subset of cancer patients. Thus, exploring the cellular and molecular mechanisms underlying the heterogeneous responses in patients can provide guidance to develop more effective oncolytic virus therapies. Single-cell RNA sequencing (scRNA-seq) analysis of tumors responsive and non-responsive to oncovirotherapy revealed signatures of the tumor immune microenvironment associated with immune response. Thus, we designed and constructed an armed oncolytic virus OV-5A that expressed five genes with non-redundant functions. OV-5A treatment exhibits robust immune response against various tumors in multiple mouse models, peripheral blood mononuclear cell (PBMC)-patient derived xenograft (PDX) model, organoid-immune cell co-culture systems and patient tissue sections by activating a cooperative innate-adaptive immune response against tumor cells. scRNA-seq analysis of complete responder and partial responder to OV-5A treatment guided the design of combination therapy of OV-5A. This data-driven approach paves a innovative way to rationalize the design of oncolytic virus and multi-agent combination therapies.
Power-split hybrid vehicles use planetary gears as power transmission and ratio devices, which are compact, efficient, and provide continuously variable gear ratio using a simple, low-cost and reliable structure. Many prominent hybrid vehicles currently on the market or under development are power-split hybrids. To take advantage of this type of hybrid power-train, it is beneficial to fully explore various configurations, select proper power-train design parameters, and obtain optimal control algorithms. This paper presents a design process that enables systematic search through all three dimensions (configuration, design and control) under imposed performance and component constraints. A case study for the design of a split hybrid vehicle with optimal fuel economy while satisfying specified driving performance is demonstrated.
Excessive biofluid and infection around wounds hinder wound healing. However, conventionally antibacterial wound dressings cannot simultaneously achieve effective biofluid control and intelligent infection treatment, tending to overhydrate wounds and develop drug-resistant bacteria due to the limitations of antibacterial components and material structures. The design of a nanozyme composite cryogel with interconnected macroporous structures, excellent designability, and lower chance of drug-resistance is greatly needed. Herein, Fe-MIL-88NH2 nanozyme is grafted to glycidyl methacrylate functionalized dialdehyde chitosan via Schiff base reaction, and acryloyl Pluronic 127 (PF127-DA) is used as a cross-linking agent to fabricate nanozyme composite cryogels (CSG-MX) as a wound dressing to enhance antibacterial and biocompatible performance for biofluid management and wound infection therapy. CSG-MX has great hydrophilicity, acid-enhanced positive charge, pH-responsive release, rebinding of nanozymes, and excellent peroxidase and oxidase mimicry activity (generation of •OH and O2•– radicals). Notably, due to the negative potential of bacteria, the impact of infection on pH value, and the enzyme-like activity as well as the reversible release of nanozymes influenced by pH, CSG-MX can achieve intelligently adaptive trapping and killing of bacteria. CSG-MX has enormous potential to be a next-generation wound dressing for biofluid management and bacterial infection treatment in the clinic.
This work analyzes the Tungsten Inert Gas (TIG)welded joint of AZ31 magnesium alloy and the pitting corrosion stress field at different depths under tensile load via the ANSYS finite element method. The strengths of the stress and strain fields inside the corrosion pit were substantially higher than the average strength level of the matrix. Therefore, under the influence of the applied load, the corrosion pit will fail first. Based on the study of pitting corrosion, a model was developed to explain how pitting corrosion cracks propagate in magnesium alloy welded joints. Finally, the variation of residual strength was revealed to study the corrosion dynamic mechanism of the joints.
A Yb:YAG-derived silica fiber with a doping concentration of 3.75 wt% for Yb 2 O 3 was fabricated by powder-in-tube method. A single-frequency fiber laser was constructed using the fiber length of 1cm with 28dB-absorption at 976nm.
In the course of searching for promising topological materials for applications in future topological electronics, we evaluated spin-orbit torques (SOTs) in high-quality sputtered $δ-$TaN/Co20Fe60B20 devices through spin-torque ferromagnetic resonance ST-FMR and spin pumping measurements. From the ST-FMR characterization we observed a significant linewidth modulation in the magnetic Co20Fe60B20 layer attributed to the charge-to-spin conversion generated from the $δ-$TaN layer. Remarkably, the spin-torque efficiency determined from ST-FMR and spin pumping measurements is as large as $Θ =$ 0.034 and 0.031, respectively. These values are over two times larger than for $α-$Ta, but almost five times lower than for $β-$Ta, which can be attributed to the low room temperature electrical resistivity $\sim 74μΩ$ cm in $δ-$TaN. A large spin diffusion length of at least $\sim8$ nm is estimated, which is comparable to the spin diffusion length in pure Ta. Comprehensive experimental analysis, together with density functional theory calculations, indicates that the origin of the pronounced SOT effect in $δ-$TaN can be mostly related to a significant contribution from the Berry curvature associated with the presence of a topically nontrivial electronic band structure in the vicinity of the Fermi level (EF). Through additional detailed theoretical analysis, we also found that an isostructural allotrope of the superconducting $δ-$TaN phase, the simple hexagonal structure, $θ-$TaN, has larger Berry curvature, and that, together with expected reasonable charge conductivity, it can also be a promising candidate for exploring a generation of spin-orbit torque magnetic random access memory as cheap, temperature stable, and highly efficient spin current sources.
Graphene has extremely high theoretical strength and electrothermal properties, and its application to Cu-based composites is expected to achieve a breakthrough in the performance of existing composites. As a nano-reinforced body, graphene often needs a long time of ball milling to make it uniformly dispersed, but the ball milling process inevitably brings damage to the graphene, causing the performance of the composite to deviate from expectations. Therefore, this paper uses CH4 as a carbon source to repair graphene through a CVD process to prepare low-damage graphene/Cu composites. The process of graphene defect generation was studied through the ball milling process. The effects of defect content and temperature on the graphene repair process were studied separately. The study found that the graphene defect repair process, the decomposition process of oxygen-containing functional groups, and the deposition process of active C atoms existed simultaneously in the CVD process. When the repair temperature was low, the C atom deposition process and the oxygen-containing functional group decomposition process dominated. In addition, when the repair temperature is high, the graphene defect repair process dominated. 3 wt% graphene/Cu composites were prepared by pressure infiltration, and it was found that the bending strength was increased by 48%, the plasticity was also slightly increased, and the thermal conductivity was increased by 10-40%. This research will help reduce graphene defects, improve the intrinsic properties of graphene, and provide theoretical guidance for the regulation of C defects in composites.
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