J. Y. Mu

National Defense Medical Center

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John R. Brobeck

Yale University

W. P. Pi

Guangxi University

Yun Hyi Ku

Korea Institute of Radiological and Medical Sciences

Hsien-wen Feng

University of Michigan–Ann Arbor

R.B. Wang

Peter G. Dayton

Boston Scientific (United States)

C.Y. Chai

Queen Mary University of London

Tsung‐Cheng Yin

Kaohsiung Chang Gung Memorial Hospital

Ching‐Hsiung Lin

Changhua Christian Hospital

F.S. Lee

Cooperative Institutions

National Defense Medical Center

Emory University

University of Pennsylvania

United States Department of Veterans Affairs

Atlanta VA Medical Center

Academia Sinica

National Taiwan University

Taipei Veterans General Hospital

University at Buffalo, State University of New York

Korea Institute of Radiological and Medical Sciences

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Uterine and hepatic protein biosynthesis in estrogen-treated and thyroidectomized rats

Clinica Chimica Acta (1972)

Hsien-wen Feng J. Y. Mu Yun Hyi Ku F.S. Lee R.B. Wang

Trichloroacetic acid

10.1016/0009-8981(72)90404-4

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Citations (1)

Blockchain Technology-Comprehensive Analysis, Applications, and Emerging Challenges

Advances in computer science research (2024)

J. Y. Mu

10.2991/978-94-6463-540-9_27

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Lipid Fractionation in Hypothalamic Obese Rats

The Chinese Journal of Physiology (1966)

K. Liu A. C. Liu J. Y. Mu

Liu, K., A. C. Liu and J. Y. Mu. Lipid fractionation in hypothalamic obese rats. Chinese J.Physiol.,19(4):371-379,1963-1966.-Studies were made on the gross elements and total lipid, phospholipid and triglyceride of muscle, liver and adipose tissue of normal and obese rats. The water content of muscle and liver washigh, and of adipose tissue was low. Great variation prevailed in total lipid and fractions, but no important difference existed between control of one and three month. Nor was there any among the lesioned of different duration. The total lipid was highest in adipose tissue, lower in liver and lowest in muscle, while phospholipid was the highest in liver with muscular one higher than adipose one. Each parameter varied randomly irrespective of the condition of the rat. Thus, the trend of change is identical with that of the duck. Adipose tissue water was discussed. The question of obesity was believed to rest on accumulation of fat in adipose tissue. In other tissues, indiscriminative variation existed with no special preference for control or lesioned. Other related points were discussed.

Muscle tissue

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Variability of body fat in hyperphagic rats.

PubMed (1968)

J. Y. Mu Tsung‐Cheng Yin Charles Hamilton John R. Brobeck

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Citations (23)

Respiratory Quotient of the Rat under Basal Conditions

The Chinese Journal of Physiology (1964)

A. C. Liu J. Y. Mu W. P. Pi

Respiratory quotient of rats was studied under pentobarbital after hypothalamic operations at different ages and after fasting 18 to 24 hours. Only with fasting up to 24 hours did R.Q. change from around 0.80to 0.70 which was not affected inspite of a higher O2 consumption for the weanling rats, though of a different strain. The higher O2 consumption indicated a faster gaseous exchange for the young while wide variationin R.Q.'s probably resulted from varying degrees of nocturnal activity and food deprivation. Both factors tended to complement each other in lowering the R.Q. to 0.70 in approximately 24 hours. Analysis of the carcasses revealed the constancy of water with respect to nonfat body weight which was correlated with O2 consumption in ml and better still with heat production in calories per 100 gm non-fat body weight. The fact that non-fat body weight is oriented more with body water and heat prodcction is in line with findings blood volume, vital capacity etc. per unit essential body mass.

Respiratory quotient

Weanling

Calorie

Basal (medicine)

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Feeding Pattern of Weanling Rats with Hypothalamic Lesions

The Chinese Journal of Physiology (1964)

W. P. Pi J. Y. Mu Ching‐Hsiung Lin PW Han A. C. Liu

Feeding pattern of weanling rats bearing hypothalamic lesions was studied. Although there was no overeating or only a delayed overeating(in the females), feeding pattern of these weanling rats was similar to that of adult rats bearing the same lesions. This was interpreted as to mean that ventromedial lesions in weanling rats also have caused hyperphagia although the overeating may be masked by the concommitant growth hormone insufficiency.

Weanling

Overeating

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The Effect of TSH on (superscript 131)I Metabolism by Human Thyroid In-vitro

The Chinese Journal of Physiology (1968)

J. Y. Mu

Mu, J. Y. The effect of TSH on (superscript 131)I metabolism by human thyroid in-vitro. Chinese J.Physiol.,20(2):157-167,1969.-The (superscript 131)I metabolism in various states of human intact thyroid and in various states of the gland in-vitro were studied. By means of organ culture technique, the morphology and biochemical activity of thyroid slices could be preserved for 12 days so far, a possible increase of seven days for observation. The differences between the effect of TSH on thyroid tissue in-vitro although detectable in thyroid tissues of different functional states, would warrent no definite conclusions until more extensive and further studies. It is clear that the organ culture tcchnique can be improved for determination of the effect of TSH on the normal or pathological thyroid tissues. Other related points have also been discussed.

Organ culture

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Thyrotropin-Like Activity of Thyroid RNA in Vitro

Experimental Biology and Medicine (1973)

C. H. Chernly J. Y. Mu

The biological effect of RNA preparations from the thyroid glands of TSH-stimulated guinea pigs was studied. In particular, iodine metabolism of the thyroid gland was stimulated by both TSH and thyroid RNA in vitro but not by liver RNA or RNase-treated thyroid RNA. The results indicate that thyroid RNA mediates the TSH stimulated iodine metabolism in the thyroid. This TSH-like effect of thyroid RNA is organ-specific and not due to contamination of RNA with TSH.

10.3181/00379727-142-37075

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Probenecid in CSF and plasma of rabbits and dogs measured by radioimmunoassay

Psychopharmacology (1977)

Wei-Shang Shei J. Y. Mu Robert F. Cunningham Zafar H. Israili Peter G. Dayton

Probenecid

10.1007/bf00492371

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Citations (4)

Cardiovascular and respiratory responses from local heating of medulla oblongata

American Journal of Physiology-Legacy Content (1965)

C.Y. Chai J. Y. Mu John R. Brobeck

The lower brain stem was explored for cardiovascular and respiratory responses by means of local diathermy in 36 urethane-anesthetized and 48 unanesthetized, decerebrate cats. In the lateral reticular formation, extending from the level of the rostral end of the inferior olivary nuclei to the most caudal portion of the medulla oblongata, localized heating decreased both rate and tidal volume of respiration, with marked bradycardia, a slight change in systolic blood pressure, and some increase in pulse pressure. Electrical stimulation of the same area usually induced forceful inspiration associated with no cardiovascular response. The thermally induced bradycardia, but not the decrease of respiration, was abolished by vagotomy or by the administration of atropine. The same diathermy applied locally to the rostral hypothalamus in the same cats evoked mainly acceleration of respiration with little cardiovascular reaction. The present experiments suggest that the lateral reticular formation of the medulla is as sensitive to thermal stimulation as is the rostral hypothalamus. The significance of the medullary thermal sensitivity, however, is not clear.

Pons

Nucleus ambiguus

Respiratory Rate

10.1152/ajplegacy.1965.209.2.301

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Citations (39)