Renal Angiomyolipoma is a common tumour in clinical practice and mostly follows a benign course. Angiomyolipoma is the most common renal neoplasm associated with spontaneous retroperitoneal haemorrhage due to rupture of micro and macro-aneurysms. Urgent trans-catheter angio-embolization of the bleeding vessel is very effective in patients suffering from life threatening hemorrhage secondary to rupture of Angiomyolipoma. Elective surgery is usually indicated to avoid re-bleeding or abscess formation. We report a case of Spontaneous Rupture of Angiomyolipoma of Right kidney in 63 years old female. The female underwent emergent Trans-arterial Embolization followed by elective nephrectomy.
Research Question: To check feasibility of urogynecologic fistula repair by minimally invasive approach. The goal of treatment of these fistulas is the rapid cessation of urine leakage with return of normal and complete urinary and genital function. Settings and design: Hospital Based Study Participants: Female patients presenting with iatrogenic urogynecologic fistula Materials and Methods: Female patients presenting with iatrogenic urogynecologic fistula formed the study group. A detailed history and physical examination was carried out. Imaging included intravenous urogram cystogram computerised tomography MR imaging and retrograde ureterogram as felt necessary. Surgical repair of ureterovaginal Vesicovaginal and Vesicouterine fistula was carried out through a laparoscopic / minimal invasive approach. Results: 14 women presented with Vesicovaginal fistulas (VVF) 7 patients presented with ureterovaginal fistula 6 women presented with vesicouterine fistula section and all underwent successful laparoscopic / minimally invasive repair of the same. The intraoperative blood loss was minimal (< 100 ml) and no major perioperative complications were noted. Conclusions: Minimally invasive approaches to repair urogynecologic fistulas are feasible safe and associated with minimal blood loss hospital stay and morbidity. (authors)
Introduction: Renal cell carcinoma presents with metastatic disease in approximately 30% of cases.Since the introduction of targeted therapies, they have demonstrated impressive gains in overall survival, progression-free survival and response rates over the previously utilized immunotherapies in cases with mRCC.The rates of cytoreductive nephrectomy have declined since the introduction of targeted therapy.We report our experience with cytoreductive nephrectomy plus targeted therapy.Materials & Methods: We retrospectively collected the hospital inpatient and outpatient records of mRCC who had undergone cytoreductive nephrectomy trailed by targeted treatment.Data included demographic, clinical, imaging and laboratory data and those that were found to have prognostic value.Measured outcomes included OS.Results: 78 patients (61 males and 17 females) 60.17± 8.76 years was mean age who underwent cytoreductive nephrectomy for mRCC of clear cell type.43 (55.1%)patients had comorbidity.78 patients had huge renal masses (mean 10.167±2.756cms) on CT imaging.All patients were introduced on target therapy four to eight weeks after surgery.The mean overall survival of the patients was 27.98±1.47months.Conclusions: Presently the important role of cytoreductive nephrectomy is not well defined in the ear of targeted therapy.However, in our study patient with good performance statuses do better than patients with existing health risks.