M A Abdelhamid

Suez Canal University

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The arrhythmic burden in patients with sarcoidosis. Is it a real concern?

Egyptian Journal of Chest Diseases and Tuberculosis (2015)

M A Abdelhamid Haytham S. Diab

Sarcoidosis is a multisystem disease characterized histologically by the formation of granulomas in many tissues. In many cases, cardiac involvement may be clinically silent but in others it may be the only clinical feature. Sudden death has been reported in 12–65% of cardiac sarcoidosis cases, and is usually attributed to malignant ventricular arrhythmias. We assessed the prevalence of cardiac arrhythmias in patients with sarcoidosis not complaining from cardiac symptoms aiming for early detection of cardiac involvement. Fifteen patients with sarcoidosis (either thoracic or extrathoracic) were enrolled in the current study. Clinical diagnosis was based on tissue biopsy. All patients were symptoms free as regards their cardiac condition. Standard ECG was done for detection of bundle branch block (BBB), or atrioventricular block. 24 h ambulatory ECG (holter) was done to detect significant premature beats (>10/h), runs of supraventricular or ventricular tachycardia (>3 beats), or ventricular fibrillation. Echocardiographic examination was done for assessment of left and right ventricle systolic and diastolic function and significant segmental wall motion abnormalities (SWMA) (>2 segments). All patients were under steroid therapy. Patients with a history of Ischemic heart disease, previous myocardial infarction (MI), congestive heart failure, electrolyte abnormalities, and patients with previously implanted permanent pacemakers or cardiac defibrillators were excluded from the study. Mean age of the study group was 49.6 ± 10.4 including 9 females and 6 male patients. Resting ECG was abnormal in 3 (20%) cases. Six patients (40%) had diastolic dysfunction however LV and RV systolic function and resting SWM were normal. No significant bradyarrhythmias were observed during holter monitoring however significant tachyarrhythmias including frequent premature atrial and ventricular beats, runs of non-sustained SVT and VT were observed in 5 patients. Life-threatening sustained VT was observed in a single patient that required Radiofrequency (RF) ablation followed by ICD implantation. Holter monitoring provides a useful, convenient and inexpensive mean of non-invasive screening for cardiac involvement in sarcoidosis especially in patients without cardiac symptoms. Extended holter should be a part of the routine work-up of any patient with sarcoidosis. The exact effect of steroid therapy on the arrhythmia burden remains a matter of debate. Cardiac MRI should be done to all patients with sarcoidosis having either abnormal symptoms or abnormal basic screening tools especially abnormal holter.

Atrioventricular block

Hypertensive heart disease

10.1016/j.ejcdt.2015.08.011

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Citations (3)

1074 Effects of endourological procedures on erectile function: A prospective cohort study

European Urology Supplements (2015)

M A Abdelhamid Mohamed Tawfik Ashraf Mosharafa Omar Abdel-Razzak

10.1016/s1569-9056(15)61062-4

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385 Value of the filtered QRS duration in patients with rheumatic mitral and or aortic regurgitation and dilated left ventricle

European Journal of Heart Failure Supplements (2004)

M A Abdelhamid S. El Bardisy H. Elhossary Hussien Rizk

10.1016/s1567-4215(04)90294-9

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Investigating the Relation Between Oil Recovery Factor in Carbonate Oil Reservoirs and Injected Water Salinity

Offshore Mediterranean Conference and Exhibition (2017)

M A Abdelhamid Osama M. Elnaggar

Oil in place

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Safety and outcome of cryoballoon ablation versus radiofrequency catheter ablation of the pulmonary veins in patients with paroxysmal atrial fibrillation

QJM (2020)

Omar Riad Tom Wong Ahmed Ali Mazen Tawfik Ibrahim M A Abdelhamid

Paroxysmal atrial fibrillation

Radiofrequency catheter ablation

10.1093/qjmed/hcaa228

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Safety and outcome of cryoballoon ablation versus radiofrequency catheter ablation of the pulmonary veins in patients with paroxysmal atrial fibrillation

QJM (2020)

Omar Riad T Wong Ahmed Ali Mazen Tawfik Ibrahim M A Abdelhamid

Abstract Background Pulmonary vein isolation (PVI) has become the mainstay of catheter ablation of atrial fibrillation (AF). There are two commonly used methods to isolate the pulmonary veins, either point-by-point delivery of circumferential lesion sets around ipsilateral pulmonary veins using radiofrequency energy, or the application of the cryoballoon to the pulmonary vein antrum with occlusion of the vein ostium. The cryoballoon has proven to be a reliable alternative to radiofrequency ablation in acute and long-term freedom from AF. We describe our results using both modalities. Aim and Objectives to compare the safety and efficacy of cryoballoon (CB) ablation and radiofrequency (RF) ablation in treatment of paroxysmal atrial fibrillation. Patients and Methods Forty-four consecutive patients having paroxysmal AF underwent PVI using the second generation cryoballoon were compared to a retrospective cohort of 69 patients who had radiofrequency induced PVI, either by conventional RF catheter (n = 32), or a contact-force sensing-catheter (n = 37). The study took place at Ain Shams university hospitals and Royal Brompton & Harefield NHS trust. Patient data, procedural data and follow up data- at 3, 6 and 12 months- were collected and analysed. Recurrence was defined as documented AF or atrial arrhythmias with duration exceeding 30 seconds, either by 12 lead ECG or an ambulatory monitoring device. Results A total of 113 patients were studied. The mean age was 53.84 ± 15.01 for the CB group and 55.78 ± 14.84 for the RF group and females representing 40.9% vs 34.8% respectively. The mean procedural times in minutes were significantly less in the CB group (94.37 ± 39.32 vs 184.57 ± 88.19, p < 0.0001), while the median fluoroscopy times were similar [30 (11.04 - 40) vs 37.25 (14.2 - 70), p = 0.172]. Procedural complications were comparable between the two groups (p = 0.06) with 1 patient (2.3%) having long term phrenic nerve paresis. At 1 year follow up, after an initial 90-day blanking period, recurrence rate of CB was similar to RF (27.3% vs 30.4% respectively, p = 0.719), the Kaplan Meier estimates of AF- free survival for a period of 1 year were comparable between both groups (log rank test, p = 0.606). Conclusion Cryoballoon is a feasible method for pulmonary vein isolation with similar success rates to radiofrequency ablation. Cryoballoon ablation is safe with shorter duration of the procedure.

Ostium

10.1093/qjmed/hcaa041.027

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Citations (1)

Sleep quality among a sample of Egyptian truck drivers

QJM (2020)

Mostafa Yosef M A Abdelhamid Waleed Salah-Eldin Mahmood M. El–Habiby Mervat Rady

Abstract Background “Road traffic accidents” is a major health problem and it is significantly related to the mean daily sleep hours and sleep quality. This study aims to explore the sleep quality among a group of Egyptian truck drivers. Methodology A convenience sample of 117 male truck drivers working on Cairo – Suez highway was selected. Socio-demographic and occupational history were collected using an interview questionnaire and the Pittsburgh sleep quality index (PSQI) was calculated. Results The mean age of the studied drivers was 38.7 ± 9.7 y, 82.1% were married and 79.5% were current smokers. The mean driving hours per day was 15.35 ± 4.77, the mean sleeping hours per day was 5.8 ± 2.3 and 48 drivers (41%) had poor sleep quality according to the cutoff 5 for PSQI questionnaire. There was a significant difference between drivers with good vs poor sleep quality regarding number of cigarettes smoked per day, hours of work per day and mean distance travelled per day. Multivariate logistic regression showed that hours of work per day was the only significant predictor with poor sleep quality. Among drivers with poor sleep quality 16.3% reported having accidents in the past year which was significantly higher (p = 0.016) than those who had good sleep quality (2.9%), Odds Ratio: 6.4, 95% CI; 1.3-31.8. Conclusion Poor sleep quality is associate with increased risk of road traffic accidents among the studied truck drivers and the main factor that affect sleep quality is the number of working hours per day.

Sleep

Affect

10.1093/qjmed/hcaa045.007

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Citations (1)

Reversal of premature ventricular complexes induced cardiomyopathy. Influence of concomitant structural heart disease

Indian Heart Journal (2017)

M A Abdelhamid Rania Samir

We examined the effect of radiofrequency (RF) catheter ablation of premature ventricular complexes (PVCs) on left ventricle (LV) function recovery in patients with LV dysfunction, regardless the presence of structural heart disease (SHD).Seventy seven patients with impaired LV ejection fraction (EF) (37.1±9.4), suspected to have PVCs cardiomyopathy (PVC-CM) (>10% PVCs burden), referred for RF ablation were enrolled, and divided into 2 groups according to the presence of SHD. SHD was ruled out by echocardiography, coronary angiography or MRI. CARTO 3 mapping system was used employing activation mapping in the majority of cases. Initial success was defined as complete elimination or residual PVCs≤10 beats/30min. Long term success was defined as reduction in PVCs burden >80% on follow-up holter. Echocardiography was done after 6 months. Improvement of EF >5% was considered significant.Forty two (55.8%) cases had SHD. PVCs burden was 28.4±9.8%. EF improved to 48.6±10.3. Initial success, overall success, post procedural PVCs burden and EF were comparable in both groups. EF improved in 47(75%) of successful cases with no significant differences between both groups. Post-MI Patients were the least category to improve. PVCs burden before and after ablation were the independent predictors of LVEF recovery by multivariate analysis. Cutoff values of >18%, <8% had 100% sensitivity and 85%, 87% specificity, respectively.PVCs elimination by RF ablation results in significant improvement even restoration of LV function regardless of PVC origin, or the presence of concomitant SHD. PVCs burden before and after ablation are the main predictors of LVEF recovery.

Concomitant

10.1016/j.ihj.2017.08.025

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Citations (7)

Assessment of right ventriclular systolic function prior to cardiac resynchronization therapy: Does it make any difference?

Indian Heart Journal (2017)

M A Abdelhamid Mazen T. Ghanem Ayman M. Abdelmotaleb

Cardiac resynchronization therapy (CRT) is an effective treatment for patients with advanced heart failure (HF). Nearly 30% of candidates are inadequate responders. The benefit of patients with right sided heart failure from CRT is still a matter of debate. We examined the effect of CRT on right ventricular (RV) dimensions and overall systolic function and whether RV function prior to CRT could have an impact on CRT response. 94 patients with a mean age of 53.7 ± 14.6 years including 19 (20%) females, with advanced HF (EF < 35%, LBBB > 120 ms, or non-LBBB > 150 ms, with NYHA –III or ambulatory class IV) were enrolled and underwent CRT implantation. Standard two dimensional (2D) echocardiography, tissue Doppler imaging, for assessment of Left ventricular (LV) end-diastolic (LVEDV), and end-systolic volumes (LVESV), ejection fraction, RV maximum basal (RVD basal), maximum mid (RVD mid) transverse, maximum longitudinal (RVD long) diameters, TAPSE, fractional area change (FAC), and tricuspid lateral annular systolic velocity (S′), in addition to RV global longitudinal strain (RVGLS) measured by speckle tracking echocardiography, were done before CRT implantation and at the end of the follow up period (5.9 ± 1.2 months). Patients presenting with reductions of LVESV of >15% were termed volumetric responders for further statistical analysis. 63 (67%) cases were volumetric responders. Both groups were matched regarding demographic, clinical, ECG, and echocardiographic criteria apart from the RV significantly smaller transverse diameters and significantly better systolic function parameters in the responders group prior to CRT compared to non-responders (NR) group. At the end of the follow up, only the responders group had further significant reduction in RV basal, mid and longitudinal diameters (33.6 ± 7.1 vs 40.7 ± 8.6, 21.4 ± 4.9 vs 27 ± 6.1, 68.3 ± 10.8 vs 81.2 ± 15, respectively), p < 0.01, together with significant improvement in RV systolic performance: FAC (47.7 ± 7.3 vs 40.9 ± 6.4), TAPSE (25.2 ± 4.6 vs 22.1 ± 4.9), S′ (15.3 ± 2.3 vs 12.8 ± 2.3), and GLS (26.1 ± 2.1 vs 18.5 ± 1.6), P < 0.01, compared to baseline readings. S' and GLS were the only independent predictors of CRT response by multivariate analysis. S′ >9 cm/s, and GLS >12.45% had 100% sensitivity and 70%, 99.7% specificity, respectively for prediction of response to CRT. CRT induces RV reverse remodeling and improves RV systolic function particularly in cardiac volumetric responders. RV systolic dysfunction before CRT implantation could identify patients that might not benefit from CRT thus helping proper patient selection and optimizing CRT response.

Doppler imaging

Speckle tracking echocardiography

Basal (medicine)

10.1016/j.ihj.2017.05.022

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Citations (8)

Using three-dimensional echocardiography to guide left ventricle lead position in cardiac resynchronization therapy: does it make any difference

Journal of Interventional Cardiac Electrophysiology (2017)

Haitham Badran John Z. Kamel Tarek Rashid Mohamed M A Abdelhamid

Concordance

Lead (geology)

10.1007/s10840-017-0229-7

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Citations (3)