Irit Krause

Tel Aviv University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Miriam Davidovits

Schneider Children's Medical Center

Roxana Cleper

Tel Aviv University

Efraim Bilavsky

Tel Aviv University

Bella Eisenstein

Schneider Children's Medical Center

Amit Dagan

Schneider Children's Medical Center

F Zintl

Friedrich Schiller University Jena

Gail Weinmann

National Heart Lung and Blood Institute

Georg Eggers

Munich University of Applied Sciences

W Dörffel

Helios Hospital Berlin-Buch

Rachel Gavish

Tel Aviv University

Cooperative Institutions

Tel Aviv University

162

Schneider Children's Medical Center

125

Rabin Medical Center

Sheba Medical Center

Tel Aviv Sourasky Medical Center

Ben-Gurion University of the Negev

Soroka Medical Center

Boston Children's Hospital

Technion – Israel Institute of Technology

University of Zagreb

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Impact of dialysis type on outcome of acute renal failure in children: a single-center experience.

PubMed (2011)

Irit Krause Naama Herman Roxana Cleper Abigail Fraser Miriam Davidovits

Acute renal failure (ARF) is a common complication in critically ill children. It is known as an important predictor of morbidity and mortality in this population. Data on the factors affecting the choice of renal replacement therapy (RRT) modality and its impact on mortality of children with ARF are limited.We retrospectively studied 115 children with ARF necessitating RRT during the period 1995-2005 to evaluate the effect of several prognostic factors as well as RRT type on their immediate outcome.The data collected from charts included demographics, primary disease, accompanying medical conditions, use of vasopressor support, indications for dialysis, RRT modality, and complications of dialysis. Categorical variables were analyzed using chi-square or Fisher's exact tests. Variables associated with mortality (P < 0.1) at the univariable level were studied by a multivariable logistic regression model.The most common cause of ARF was congenital heart disease (n=75). RRT modalities included peritoneal dialysis (PD) (n=81), hemodialfiltration (HDF) (n=31) and intermittent hemodialysis (IHD) (n=18). Median RRT duration was 4 days (range 1-63 days). Overall mortality was 52.2%. IHD was associated with the best survival rate (P < 0.01 vs. PD and HDF), while children treated with HDF had the worse outcome. Hemodynamic instability and systemic infections were associated with greater mortality, but the rate of these complications did not differ between the study groups.Our results suggest that IHD when applied to the right patient in an appropriate setting may be a safe and efficient RRT modality in children with ARF. Randomized prospective trials are needed to further evaluate the impact of different RRT modalities on outcome in children with ARF.

Renal replacement therapy

Single Center

Source

Cite

Citations (8)

Pediatrician, watch out for corona-phobia

European Journal of Pediatrics (2020)

Chen Rosenberg Danziger Irit Krause Oded Scheuerman Anthony Luder Alon Yulevich

Pandemic

Isolation

Virus diseases

Social distance

10.1007/s00431-020-03736-y

Cite

Citations (18)

KINGELLA KINGAE OCCULT BACTEREMIA IN A TODDLER

The Pediatric Infectious Disease Journal (1996)

Irit Krause Revital Nimri

To The Editors: Kingella kingae has been recognized with increasing frequency as a pathogen of invasive infections in early childhood.1 It causes septic arthritis, osteomyelitis, endocarditis and other focal infections,1-4 but only a few patients with occult bacteremia have been described.1-5 Some authors advocate active search for an endocardial focus whenever K. kingae is isolated in blood culture.6 Yagupsky et al.5 reported seven children with K. kingae occult bacteremia without endocarditis and pointed out that all bacteremic children in their series and in previous studies were younger than age 12 months. It was suggested that the symptoms related to K. kingae bacteremia are age-dependent; i.e. older children are not symptomatic. Recently we treated in our hospital a 2-year, 8-month-old girl who had K. kingae bacteremia. This previously healthy girl had a fever (39.3°C), vomiting and watery diarrhea for 2 days. No other family members were affected and there was no history of travel. The patient was in good general condition. Small ulcers were noted on the buccal mucosa. There were no signs of arthritis, osteomyelitis or endocarditis. The white blood cell count was 9500/mm3 with 60% neutrophils. Blood culture obtained at admission, inoculated into aerobic culture medium (Becton Dickinson), yielded K. kingae, which was susceptible to penicillin, cephalosporins and aminoglycosides. K. kingae was identified on the basis of a typical Gram-stained smear, beta-hemolysis, positive oxidase reaction, negative catalase and urease and fermentation of glucose and maltose. The patient was treated with cefuroxime for 10 days. The symptoms subsided within 24 h and subsequent blood cultures showed no growth. Echocardiographic examination was normal. Our patient presented with fever, diarrhea and aphtous stomatitis, features previously found in association with K. kingae bacteremia.5 To our knowledge K. kingae occult bacteremia has not yet been reported in children older than 12 months. The rarity of K. kingae occult bacteremia in children older than 12 months might be explained by several factors: (1) milder symptoms in older children; (2) blood cultures obtained more frequently in febrile infants under the age of 12 months; and (3) low awareness of this pathogen and regarding it as contaminant. We think that it is important for pediatricians to be aware of K. kingae as a possible pathogen of occult bacteremia in infants and young children. Irit Krause, M.D.; Revital Nimri, M.D. Schneider Children's Medical Center of Israel Petah-Tiqva, Israel

Bacteremia

Kingella kingae

Blood Culture

10.1097/00006454-199606000-00027

Cite

Citations (6)

[Postoperative rupture of the abdominal wall in children (author's transl)].

PubMed (1977)

Irit Krause

An evaluation of 105 cases of abdominal wound rupture is reported which represents 1.9% of a total of 5,552 laparotomies performed in children during the years 1960 to 1975. Most ruptures occurred in infants. Prior to other reasons, the frequency seems to depend on the original disease. 23% of the cases, predominantly newborns and infants, had a lethal course.

Source

Cite

Citations (0)

[Liver damage due to methionine overdosage].

Klinische Wochenschrift (1951)

L. Heller Irit Krause

Human genetics

10.1007/bf01483966

Cite

Citations (3)

Ocular complications in children and adolescents following renal transplantation

Pediatric Transplantation (2009)

Irit Krause Moshe Snir Roxana Cleper Abigail Fraser Yael Kovalski

Krause I, Snir M, Cleper R, Fraser A, Kovalski Y, Axer Siegel R, Bar-Nathan N, Davidovits M. Ocular complications in children and adolescents following renal transplantation.Pediatr Transplantation 2010: 14: 77–81. © 2009 Wiley Periodicals, Inc. Abstract: Ocular complications after renal transplantation are common in adults. Nevertheless, data regarding these complications in children are insufficient. The purpose of the present study was to assess ocular morbidity in pediatric renal graft recipients. A retrospective observational study of 71 patients aged 11.2 ± 5.5 yr was conducted. Mean duration of follow-up was 5.6 ± 3.5 yr. A total of 16 ocular complications were found in 12 (17%) of the patients. Three patients suffered from more than one complication. Cataract was the most common finding (six patients, 8.4%) followed by swollen disk and hypertensive retinopathy in four patients (5.7%) each and increased intra-ocular pressure in two patients (3%). Mean time interval between transplantation and occurrence of first abnormal ocular finding was 37 ± 34.5 months. The follow-up time was significantly longer in patients with ophthalmological problems than in those without complications (7.8 yr vs. 5.2 yr, p < 0.02). No statistically significant association was found between the occurrence of ocular complications and the age of the patients at transplantation, donor source, duration of dialysis prior to transplantation, previous corticosteroid therapy or presence of acute rejection episodes. The results of the study point to the importance of regular concurrent ophthalmological follow-up in pediatric renal graft recipients to reduce/prevent ocular morbidity.

10.1111/j.1399-3046.2008.01126.x

Cite

Citations (17)

Long-term outcomes during 37 years of pediatric kidney transplantation: a cohort study comparing ethnic groups

Pediatric Nephrology (2021)

Miriam Davidovits Lewis Reisman Roxana Cleper N Bar-Nathan Irit Krause

Nephrology

10.1007/s00467-020-04908-6

Cite

Citations (9)

Impact of Pediatric Chronic Dialysis on Long-Term Patient Outcome: Single Center Study

International Journal of Nephrology (2016)

Daniella Levy Erez Irit Krause Amit Dagan Roxana Cleper Yafa Falush

Objective. Owing to a shortage of kidney donors in Israel, children with end-stage renal disease (ESRD) may stay on maintenance dialysis for a considerable time, placing them at a significant risk. The aim of this study was to understand the causes of mortality. Study Design . Clinical data were collected retrospectively from the files of children on chronic dialysis (>3 months) during the years 1995–2013 at a single pediatric medical center. Results. 110 patients were enrolled in the study. Mean age was10.7±5.27 yrs. (range: 1 month–24 yrs). Forty-five children (42%) had dysplastic kidneys and 19 (17.5%) had focal segmental glomerulosclerosis. Twenty-five (22.7%) received peritoneal dialysis, 59 (53.6%) hemodialysis, and 6 (23.6%) both modalities sequentially. Median dialysis duration was 1.46 years (range: 0.25–17.54 years). Mean follow-up was13.5±5.84 yrs. Seventy-nine patients (71.8%) underwent successful transplantation, 10 (11.2%) had graft failure, and 8 (7.3%) continued dialysis without transplantation. Twelve patients (10.9%) died: 8 of dialysis-associated complications and 4 of their primary illness. The 5-year survival rate was 84%: 90%for patients older than 5 years and 61%for younger patients. Conclusions. Chronic dialysis is a suitable temporary option for children awaiting renal transplantation. Although overall long-term survival rate is high, very young children are at high risk for life-threatening dialysis-associated complications.

Single Center

Chronic renal failure

10.1155/2016/2132387

Cite

Citations (6)

[Problem of abdominal actinomycosis].

PubMed (1957)

Irit Krause

Actinomycosis

Source

Cite

Citations (0)