Mazrura Sahani

National University of Malaysia

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Mohd Talib Latif

National University of Malaysia

Rozita Hod

National University of Malaysia

Md Firoz Khan

North South University

Hidayatulfathi Othman

National University of Malaysia

Wan Rozita Wan Mahiyuddin

Ministry of Health

Muhammad Ikram A. Wahab

National University of Malaysia

Murnira Othman

National University of Malaysia

Mohd Shahrul Mohd Nadzir

National University of Malaysia

Norhaniza Amil

Universiti Sains Malaysia

Asmalia Md Lasim

Institute for Medical Research

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National University of Malaysia

137

Ministry of Health

University of Malaya

NOAA Physical Sciences Laboratory

University Kebangsaan Malaysia Medical Centre

National Institutes of Biotechnology Malaysia

John Wiley & Sons (United States)

Universiti Putra Malaysia

Institute for Medical Research

Universiti Malaysia Terengganu

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Negative selection algorithm for dengue outbreak detection

TURKISH JOURNAL OF ELECTRICAL ENGINEERING & COMPUTER SCIENCES (2013)

Maryam Mousavi Azuraliza Abu Bakar Suhaila Zainudin Zalizah Awang Long Mazrura Sahani

Dengue is a critical communicable and vector-borne disease and is becoming a serious concern in Malaysia. It is important to have an early detection system that could provide immediate action, such as the control of dengue transmission at a specific location. However, the available strategy and action may give long-term effects to the community since inaccurate decision making or prediction may lead to other circumstances. Moreover, the need to have a system that can detect the outbreak in a reasonable amount of time is critical. In this study, a nature-inspired computing technique, the artificial immune system (AIS), is used for dengue outbreak detection. One of the variants of the AIS algorithms, called the negative selection algorithm (NSA), has been widely applied in anomaly detection and fault detection. This study aims to employ the NSA for dengue outbreak detection.

10.3906/elk-1206-91

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Citations (9)

Seasonal effect and source apportionment of polycyclic aromatic hydrocarbons in PM2.5

Atmospheric Environment (2015)

Md Firoz Khan Mohd Talib Latif Chee Hou Lim Norhaniza Amil Shoffian Amin Jaafar

10.1016/j.atmosenv.2015.01.077

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Citations (180)

PENGGUNAAN KAEDAH PENYEBARAN-AUTO SEPARA LAPANGAN DAN SIMULASI LAPANGAN TERHADAP VEKTOR DEMAM DENGGI Aedes aegypti (LINNAEUS) (DIPTERA: CULICIDAE)

Serangga (2020)

Ahmad Mohiddin Mohd Ngesom Wan Norkamila Wan Hanif Asmalia Md Lasim Mazrura Sahani Rozita Hod

Demam denggi merupakan penyakit bawaan nyamuk yang menunjukkan kesan signifikan terhadap manusia serta meningkatkan kebimbangan kesihatan awam. Namun begitu, kawalan vektor sedia ada belum mampu mengurangkan jangkitan denggi, menunjukkan kaedah yang digunakan masih tidak mencukupi dan perlu dinilai semula. Penyebaran-auto dengan pyriproxyfen merupakan satu kaedah novel yang memanipulasi nyamuk untuk menyebarkan pyriproxyfen ke bekas pembiakan. Kaedah ini bergantung sepenuhnya kepada kelakuan langkau oviposisi nyamuk Aedes spp. semasa ingin bertelur. Kajian ini dijalankan untuk menguji potensi Mosquito Home System (MHS) dan formulasi Mosquito Home Aqua (MHAQ) sebagai stesen penyebaran-auto dalam keadaan separa-lapangan. Selain itu, impak penggunaan terhadap populasi nyamuk di lapangan turut diakses. Ujian separa lapangan telah dijalankan dalam bilik berdasarkan kepada konsep kebuk peet grady yang disimulasikan sebagai aparment bertingkat di Kuala Lumpur menggunakan sangkar besar. Ujian menunjukkan kecenderungan nyamuk Ae. aegypti liar bertelur dibekas tersembunyi (69.88%) berbanding bekas terbuka (30.12%). Tiada perbezaan yang signifikan di antara pyriproxyfen dan air seduhan rumput kering menunjukkan kebolehan menarik nyamuk ke dalam stesen. Penggunaan pyriproxyfen pada 20 dan 40 ppm menunjukkan kesan residu yang setara sehingga 90 hari berbanding 0.5 dan satu ppm. Dalam simulasi lapangan, dua penetapan lokasi kawalan dan rawatan telah ditentukan. Kaedah percubaan kawalan rawak dijalankan dengan memasang stesen penyebaran-auto di lokasi kajian dan populasi nyamuk seterusnya dipantau. Ujian dengan kepekatan 40 ppm menunjukkan penurunan dalam populasi nyamuk dan kematian larva dari sampel air yang diambil dari lokasi kajian. Selain itu, aktiviti perpindahan pyriproxyfen secara horizontal di separa lapangan dan simulasi lapangan diakses menggunakan bioasai larva WHO. Keputusan membuktikan kebolehan pyriproxyfen dipindahkan ke kawasan pembiakan baru dilokasi kajian. Kajian ini telah membuktikan potensi MHS sebagai alat penyebaran-auto yang berupaya menarik perhatian nyamuk dan seterusnya memindahkan insektisid ke bekas pembiakan yang lain. Kajian MHS pada skala yang lebih besar adalah diperlukan sebelum boleh dipertimbangkan sebagai alternatif dalam program kawalan vektor.

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Ambient volatile organic compounds in tropical environments: Potential sources, composition and impacts – A review

Chemosphere (2021)

Norfazrin Mohd Hanif Nor Syamimi Sufiera Limi Hawari Murnira Othman Haris Hafizal Abd Hamid Fatimah Ahamad

Isoprene

BTEX

Bromoform

Volatile organic compound

Dimethyl sulfide

10.1016/j.chemosphere.2021.131355

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Citations (58)

Influences of inorganic and polycyclic aromatic hydrocarbons on the sources of PM2.5 in the Southeast Asian urban sites

Air Quality Atmosphere & Health (2017)

Md Firoz Khan Saw Wuan Hwa Lim Chee Hou Nur Ili Hamizah Mustaffa Norhaniza Amil

Fluoranthene

10.1007/s11869-017-0489-5

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Citations (29)

Methodology in Assessing the Health Risks on Proposed Water Resource Developments in Malaysia

Epidemiology (2010)

Mazrura Sahani Hidayatulfathi Othman Omar Baharuddin Rozita Hod Abdullah Aini

PP-31-143 Background/Aims: Methodology in assessing the risks of proposed water resource developments to the health of the community in Malaysia is being develop. This assessment aims to evaluate the potential impacts of the few water resource developments to the health of the community within the zone of influence. Methods: Our assessment methodologies consist of descriptive epidemiology on the existing human environment and the prediction of the health risks from the proposed development. Data on burden of diseases and the community profiles and other health determinants provide the baseline for the existing community health status. These data were obtained through a house to house survey and a secondary data review. For waterborne diseases, the prevalence of intestinal parasite infections among children of the affected community is determined. The ecology of mosquito vectors is determined using the 3 different techniques: bare leg catch, CDC light trap, and larval survey. Schistosomiasis and zoonotic studies could also be carried out. Results: The community health risks to these communicable diseases are qualitatively determined. The quantitative health risk assessment is applied to any water supply project. The quantitative health risk assessment is applied to any water supply project. The emerging and re-emerging diseases and community participation also need to be addressed. Conclusion: The health risk assessment methodology is important for policy direction and decision-making in the environmental management for health.

Community Health

Health assessment

Health Impact Assessment

10.1097/01.ede.0000392143.35633.97

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A Review: Autodissemination of Pyriproxyfen as Novel Strategy to Control Dengue Outbreaks

Pertanika journal of science & technology (2020)

Ahmad Mohiddin Mohd Ngesom David Greenhalgh Asmalia Md Lasim Mazrura Sahani Rozita Hod

The new emergence and re-emergence of arbovirus infections transmitted by Aedes mosquitoes have been spreading across Southeast Asia, Central Africa, United States, tropical Oceania and has become a major of public health concern. These arbovirus diseases were found to have a similar vector, symptoms, and environments. The situation is complex due to no specific vaccine or treatments being available for the diseases. Therefore, vector control is currently the best defense against arbovirus diseases, but with its own challenges such as the difficulty in controlling scattered breeding sites and biological behavior. Herein, we present a literature review of studies on current techniques proposed to combat dengue transmission that can fill a crucial gap in vector control programs, which is the inability of conventional control methods to eliminate and destroy cryptic breeding sites. In particular, we focused on the concept of autodissemination, which is a self-delivery technique by manipulating the behavior of mosquitoes, carrying the insecticide and disseminating it to cryptic breeding sites. This technique has shown promising results in some countries and can be considered as an additional tool in a vector control program. Therefore, we conducted Boolean searches in several electronic databases including Google Scholar, PubMed, SciELO and ScienceDirect to identify relevant published data regarding dengue and autodissemination techniques.

10.47836/pjst.28.4.01

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Citations (4)

Metodologi kuantitatif dalam mengkomputasi impak sosio-ekonomi perubahan iklim kepada kesihatan manusia

Ah Choy Er Asmahani Atan Nur Salihah Kassim Mazrura Sahani

Di negara sedang membangun mahupun di negara membangun, penilaian di peringkat nasional bagi potensi kesan perubahan iklim ke atas kesihatan manusia masih terhad. Limitasi juga merangkumi agihan reruang penyakit kesan daripada perubahan iklim. Penilaian di peringkat nasional untuk menilai risiko perubahan iklim memudahkan pembuat dasar mengamalkan respons adaptatif, faedah bersama dan mitigasi. Antara lain, respons adaptatif, faedah bersama dan mitigasi dari segi polisi, strategi dan langkah-langkah perlu dilaksanakan pada masa kini dan juga bagi generasi akan datang demi mengurangkan potensi kesan terhadap kesihatan yang merugikan. Tambahan pula, masih kekurangan kajian atau penilaian di peringkat nasional bagi impak sosioekonomi dan kos sosio-ekonomi yang berkaitan akibat perubahan iklim ke atas kesihatan manusia. Berdasarkan literatur yang sedia ada, data dan maklumat berkaitan kesan perubahan iklim ke atas keakhiran kesihatan manusia (health outcomes), dan terutamanya respons masih terhad. Malahan, data dan maklumat berkaitan kuantifikasi impak sosio-ekonomi dalam Ringgit Malaysia masih terhad. Kebanyakan kajian mengenai perubahan iklim dan kesihatan manusia adalah daripada perspektif sains bukan sains sosial. Pada masa yang sama, kajian-kajian berkaitan kuantifikasi sosio-ekonomi dan metodologi yang berkaitan, termasuk proksii, yang dilakukan oleh pengkaji di negara membangun dan negara sedang membangun mungkin tidak relevan dalam konteks Malaysia. Kertas kerja ini bertujuan mengupas kajian keperpustakaan tentang metodologi untuk mengkuantifikasikan impak sosio-ekonomi perubahan iklim ke atas keakhiran kesihatan manusia.

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Knowledge and Practices Regarding Aedes Control Amongst Residents of Dengue Hotspot Areas in Selangor: A Cross-Sectional Study

Sains Malaysiana (2019)

Zul-‘Izzat Ikhwan Zaini Hidayatulfathi Othman Norhafizah Karim Nor Azimah Abd Rashid Mohamad Badrul Hisham Abas

Dengue fever is endemic and remains a public health concern in Malaysia.The highest number of dengue cases occurred in Selangor in 2015.The majority of hotspot and outbreak areas in Malaysia were located in residential areas.Despite the high number of dengue prevalence in Malaysia, evidence for the level of community knowledge and practice of methods for Aedes control and prevention in the country remains scant.This cross-sectional study aimed to assess the demographic factors associated with the knowledge and practice of Aedes control and prevention methods.It also aimed to assess the associations and relationships between the public knowledge and practice of Aedes control and preventive activities involving Aedes larvae ovitraps (ALOTs), Mousticide, Denguard and other methods.Two residential areas that were considered as dengue hotspots were selected for the introduction of Aedes control and prevention programs.A sample size was calculated using G*power and a total of 152 residents who attended the dengue awareness events held at Section 3 and Section 8, Bandar Baru Bangi, Selangor, were recruited.A purposive sampling approach was adopted, and data were collected by using a pretested questionnaire with three subsections on sociodemographic information and on the knowledge and practice of Aedes control and prevention methods.No statistically significant (p>0.05)relationship between demographic factors and knowledge and practice scores was found.The results of χ 2 square test showed a strong (φ-coefficient = 0.605) and significant (p<0.001)association between knowledge and practice scores.In addition, a strong and significant positive correlation (r=0.648,p<0.001) existed between knowledge and practice scores.In conclusion, health promotion programs that focus on educating the public regarding the use of Aedes larvae ovitraps (ALOTs), Mousticide, Denguard and other methods to prevent and control Aedes mosquitoes and that involve multiple stakeholders, such as government officials and responsible authorities, and the active participation of communities are crucial in the war against Aedes.

Cross-sectional study

10.17576/jsm-2019-4804-16

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Citations (12)

The association between temperature and cause-specific mortality in the Klang Valley, Malaysia

Environmental Science and Pollution Research (2021)

Ahmad Norazhar Mohd Yatim Mohd Talib Latif Nurzawani Md Sofwan Fatimah Ahamad Md Firoz Khan

Apparent temperature

Distributed lag

10.1007/s11356-021-14962-8

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Citations (17)