Lambros Vlahos

National and Kapodistrian University of Athens

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Kyriaki Mystakidou

National and Kapodistrian University of Athens

Efi Parpa

Alexandra Hospital

Eleni Tsilika

National and Kapodistrian University of Athens

John Kouvaris

National and Kapodistrian University of Athens

Emmanuela Katsouda

National and Kapodistrian University of Athens

Vassilis Kouloulias

National and Kapodistrian University of Athens

Antonis Galanos

National and Kapodistrian University of Athens

A. Gouliamos

National and Kapodistrian University of Athens

A. Gouliamos

Aretaeio Hospital

A. Kalovidouris

National and Kapodistrian University of Athens

Cooperative Institutions

National and Kapodistrian University of Athens

233

Aretaeio Hospital

128

Athens State University

Panteion University

University General Hospital Attikon

Athens Medical Center

Eginition Hospital

Alexandra Hospital

National Technical University of Athens

Ludwig-Maximilians-Universität München

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Cytoprotective Effect of Amifostine in Radiation-Induced Acute Mucositis – a Retrospective Analysis

Oncology Research and Treatment (2002)

John Kouvaris Vassilis Kouloulias John Kokakis George K. Matsopoulos M. Balafouta

To study the cytoprotective impact of amifostine against acute radiation mucositis.A total of 117 cancer patients with carcinomas localized in pelvic organs, lung and head and neck were entered into this study. In a retrospective way, and in order to minimize the bias related to the investigator, 138 patients as historical controls were randomly selected from a database in our hospital. Acute radiation-induced gastrointestinal mucositis, esophagitis and stomatitis were assessed using the common toxicity criteria scale. The most severe grade recorded was evaluated as the final morbidity score for this patient. Mean toxicity score (MTS) was the mean value of recorded acute radiation toxicity. Mean interruption time (MIT) was the mean value of recorded interruption time due to radiation toxicity.A significantly reduced severity of symptomatology related to oral, esophageal and rectal mucosa was noted in the amifostine group (group A) (p < 0.05, chi-square test). Furthermore, a significant reduction of MTS as well as MIT was observed in group A versus the historical controls (group B) (p < 0.05, Mann-Whitney U test).The administration of amifostine seems to protect patients against radiation-induced mucositis, but further investigation with randomized trials is needed.

Mucositis

Amifostine

Esophagitis

10.1159/000066055

Cite

Citations (20)

Phase II multicenter randomized study of amifostine for prevention of acute radiation rectal toxicity: Topical intrarectal versus subcutaneous application

International Journal of Radiation Oncology*Biology*Physics (2005)

Vassilis Kouloulias John Kouvaris George Pissakas Elias Mallas Christos Antypas

Amifostine

Mucositis

Enema

10.1016/j.ijrobp.2004.10.043

Cite

Citations (49)

Solitary Brain Metastasis from Classic Biphasic Pulmonary Blastoma: A Case Report and Review of the Literature

Oncology Research and Treatment (2006)

John Kouvaris Penelope Gogou Xenofon N. Papacharalampous Helen J. Kostara M. Balafouta

Background: Classic biphasic pulmonary blastoma (CBPB) is a rare and aggressive primary malignancy, brain metastases of this type of tumor are even rarer. Case Report: A 51-year-old male patient with a solitary cerebral metastasis, diagnosed ten months after left pneumonectomy for a CBPB, was treated by surgery and accelerated hypofractionated radiotherapy. Results: The patient died 15 months after partial removal of the brain metastasis. Literature review revealed only 4 cases of solitary brain metastases from this type of malignancy. The present case is the second one reported with a combined treatment of surgery and radiotherapy resulting in the longest survival. Conclusion: The best treatment for CBPB is difficult to determine because of the small number of cases, however, the combination of surgery with radiotherapy seems to be effective. The effectiveness of chemotherapy has not been ascertained.

10.1159/000096708

Cite

Citations (15)

Post‐traumatic growth in advanced cancer patients receiving palliative care

British Journal of Health Psychology (2008)

Kyriaki Mystakidou Eleni Tsilika Efi Parpa Antonis Galanos Lambros Vlahos

To develop the Greek version of the Post-traumatic Growth Inventory (PTGI-Gr), and assess its psychometric properties in a palliative care patient sample.The scale was translated with the forward-backward procedure to Greek. It was administered twice, with a 3-day interval, to 131 eligible patients with advanced cancer. Together with the PTGI, the patients also completed the Greek version of the Impact of Events Scale-Revised scale (IES-R-Gr). The reliability was assessed by the internal consistency (Cronbach's alpha coefficients), test/retest (Spearman's r value), and inter-item correlations. Validity was demonstrated by factor analysis, inter-scale correlations, construct validity with the IES-R-Gr, and combined with the Eastern Cooperative Oncology Group (ECOG) performance status.The PTGI-Gr yielded a five-factor structure, explaining 73.5% of the variance. Cronbach's alphas for the five factors ranged from .66 to .87, respectively. Overall test-retest reliability was satisfactory with a range between .85 and .92 (p<.0005), and inter-item correlations ranged between .47 and .63. Inter-scale correlations were found satisfactory (p<.0005, p<.005, and p<.05). Validity as performed using combined validity analysis showed good results. Satisfactory construct validity was supported by the correlation analysis between the PTGI-Gr and the IES-R-Gr scales.PTGI-Gr is an instrument with satisfactory psychometric properties, and is a valid research tool for the post-traumatic growth of advanced cancer patients.

Item analysis

10.1348/135910707x246177

Cite

Citations (49)

Treatment of unresectable liver metastases with transhepatic radionuclide infusions: Preliminary experience

Georgios S. Limouris Panagiotis Sideras Christoforos Panayides Konstantinos Roussopoulos Loukas Lamprakos

1801 Objectives: Transhepatic radionuclide infusion (THRI) was introduced as a new treatment approach for unresectable liver neuroendocrine metastatic lesions. Methods: In 19 patients , multiple liver neuroendocrine metastases were locally treated by using a transhepatic approach. After femoral artery puncture, tumor-supplying hepatic arteries were selectively catheterized, and 5.5± 7.03±3 GBq of In-111 Octreotide was infused. Follow-up at monthly intervals was performed by means of ultrasonography (US) and every six months by contrast material-enhanced computed tomography (CT). Results: Treatment was well tolerated in all patients without any side effects or complications. By using RECIST criteria disease complete response was achieved in 2 patients, partial response in 12, while stable disease was recorded in 1 patient. In 4 patients disease progression was revealed and all 4 died approximately 4 to 7 months after the initialization of the therapeutic scheme. Conclusions: THRI seems to be a well-tolerated palliative treatment option in patient with small to moderate in size liver neuroendocrine metastases.

Radionuclide therapy

Cite

Citations (0)

Archives of Psychiatric Nursing (2008)

Kyriaki Mystakidou Eleni Tsilika Efi Parpa Paraskevi Athanasouli Antonis Galanos

Depression

Traumatic Grief

10.1016/j.apnu.2008.04.008

Cite

Citations (44)

Original article Right adrenal hematoma following hepatectomy

A. Gouliamos Anna Metafa S. G. Ispanopoulou F. Stamatelopoulou Lambros Vlahos

We present the findings and possible causes in three cases of postoperative adrenal hematomas. In 16 cases of 45 consecutive patients, following seg- mental right or left lobe hepatectomy, CT was per- formed in order to evaluate possible fluid collection or other complications. In all cases imaging findings and a correlation with preoperative CT scans were done. Follow-up CT examinations were also re- viewed. In three cases solid suprarenal masses with attenuation values consistent with adrenal hemato- mas were found. Preoperative scans at the same level indicated normal adrenal glands. Follow-up scans re- vealed the hematoma, stable in size, for up to 12 weeks, although lower attenuation values were ev- ident. Right adrenal hematoma is a possible postop- erative complication following hepatectomy; if it re- mains stable in size, it can be left alone.

Left lobe

Source

Cite

Citations (0)

Traumatic Distress and Positive Changes in Advanced Cancer Patients

American Journal of Hospice and Palliative Medicine® (2007)

Kyriaki Mystakidou Efi Parpa Eleni Tsilika Maria Pathiaki Antonis Galanos

This study investigated the traumatic distress and posttraumatic growth in 58 advanced cancer patients receiving palliative treatment in a Pain Relief and Palliative Care Unit. The patients completed the Greek version of the Impact of Events Scale-Revised and the Posttraumatic Growth Inventory. Statistically significant associations were found among Impact of Events Scale-Revised-Greek "Relating to Others" (r = 0.311, P = .017), "New Possibilities" ( r = 0.248, P = .050), and "Appreciation of Life" ( r = 0.419, P = .001), and the Posttraumatic Growth Inventory scores (r = 0.323, P = .013). Similarly, "Appreciation of Life" correlated significantly with "Avoidance" (r = 0.318, P = .015), "Intrusion" (r = 0.365, P = .005), and "Hyperarousal" (r = 0.398, P = .002). Statistically significant associations were also found between "Relating to Others" and "Intrusion" (r = 0.414, P = .001). The study concluded that in advanced cancer patients, the higher the impact event, the more improvement in their relationships with others, enhanced life appreciation, and more positive consequences after trauma.

10.1177/1049909107299917

Cite

Citations (35)

Imaging of a supernumerary kidney

European Radiology (2000)

Ανδρέας Κουρέας Evangelia Panourgias A. Gouliamos S. Trakadas Lambros Vlahos

Neuroradiology

Interventional radiology

Pyelogram

Quadrant (abdomen)

Ultrasonogram

10.1007/s003300000439

Cite

Citations (29)

Self-efficacy beliefs and levels of anxiety in advanced cancer patients

European Journal of Cancer Care (2009)

Kyriaki Mystakidou Eleni Tsilika Efi Parpa Penelope Gogou Pavlos N. Theodorakis

The aims of this study were to investigate the self-efficacy and anxiety in advanced cancer patients in a palliative care unit. The subject is some 99 advanced cancer patients, treated for pain relief and cancer-related symptoms. Patients completed the General Perceived Self-Efficacy Scale (GSE) and the Spielberger's State-Trait Anxiety Inventory (STAI). The Eastern Cooperative Oncology Group was used to measure patients' performance status. Statistically significant associations were found between GSE, patients' gender, performance status, opioids and all the STAI scales. The multiple regression analysis revealed that self-efficacy was predicted by patients' age, performance status, gender, as well as by their high levels on two STAI scales, in a model explaining 39.7% of the total variance. In advanced cancer patients, self-efficacy is significantly correlated with levels of anxiety, patients' physical condition and demographic characteristics. Also, it seems to be influenced by components of the STAI, patients' age, physical performance and gender.

Self-Efficacy

10.1111/j.1365-2354.2008.01039.x

Cite

Citations (46)