P. Métézeau

Institut Pasteur

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F Tazieff-Depierre

Institut de Médecine et d'Epidémiologie Africaines

Danièle Goudou

Université Paris-Sud

Hélène Kiefer

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

M.E. Goldberg

Foundation Medicine (United States)

Richard Chaby

Centre National de la Recherche Scientifique

I. Elguindi

Piotr P. Słonimski

University of Tennessee Health Science Center

Robert Girard

Université Grenoble Alpes

Patrice X. Petit

Institut Cochin

Nathalie Glab

Centre National de la Recherche Scientifique

Cooperative Institutions

Centre National de la Recherche Scientifique

Inserm

Institut Pasteur

Université Paris Cité

Sorbonne Université

Université Paris-Sud

Université Paris-Saclay

École Pratique des Hautes Études

Centre de Génétique Moléculaire

Pitié-Salpêtrière Hospital

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Modulation of fibroblast response to maitotoxin along the cell division cycle

Cell Biology and Toxicology (1994)

J. Berreur‐Bonnenfant M. Ammar A Dubreuil Hélène Kiefer Jorge Diogène

Ionomycin

3T3 cells

10.1007/bf00755792

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Citations (2)

[Cytometry and oncology: technical approaches, importance and limitations, perspectives].

PubMed (2001)

P. Métézeau Philippe Vielh

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Citations (0)

Practical flow cytometry

Annales de l Institut Pasteur Microbiologie (1988)

P. Métézeau

Bovine serum albumin

10.1016/0769-2609(88)90163-9

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Citations (91)

Modulation of membrane receptor endocytosis by chemical effectors of membrane fluidity

Biology of the Cell (1985)

I. Elguindi Gérard Redziniak P. Métézeau Alain Meybeck M.E. Goldberg

Several chemical effectors were used to induce changes in spleen B cell membrane fluidity. Membrane fluidity was monitored by fluorescence polarization analysis of the hydrophobic probe 1,6-diphenyl-1,3,5-hexatriene (DPH) and cell viability was checked not to be affected by the treatments. Membrane immunoglobulin (Ig) endocytosis by the living B cells with modified or unmodified membranes was quantitatively measured by flow cytometry, using a previously described method (Métézeau et al., 1982, 1984). The kinetics of endocytosis of membrane Ig was not affected by chemical effectors increasing membrane fluidity. On the contrary, increasing membrane microviscosity resulted in the slowing down and eventually the blocking of membrane Ig endocytosis. It is suggested that a step depending on membrane microviscosity is involved in the process of endocytosis; this step may become rate limiting when membranes are artificially rendered or naturally become (i.e. for pathological or particularly differentiated cells) more viscous.

10.1111/j.1768-322x.1985.tb00395.x

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Citations (16)

Practical flow cytometry

Annales de l Institut Pasteur Immunologie (1988)

P. Métézeau

10.1016/0769-2625(88)90111-0

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Citations (163)

The kinetics and homogeneity of endocytosis of a receptor-bound ligand in a heterogeneous cell population studied by flow cytofluorometry.

Journal of Histochemistry & Cytochemistry (1982)

P. Métézeau Lisa Djavadi‐Ohaniance M.E. Goldberg

A method is described to study quantitatively and rapidly the kinetics of endocytosis of a receptor-bound ligand by cells of various subclasses within a heterogeneous cell population. The time course of the internalization of the bound ligand is followed by labeling, with a fluorescent antibody, the ligand molecules exposed on the cell surface at various times of the endocytosis process, and by measuring with a flow cytofluorometer the fluorescence of a large number of individual cell within the total cell population. A convenient mathematical treatment of the data is proposed for analyzing the experimental results. This method is applied to the kinetic study of the endocytosis of rabbit antibodies (anti-mouse immunoglobulin) by B-lymphocytes within a mouse spleen cell suspension.

Internalization

Receptor–ligand kinetics

10.1177/30.4.7061830

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Citations (12)

Heterogeneity of mouse thy 1.2 antigen expression revealed by monoclonal antibodies

Cellular Immunology (1982)

Paolo del Guercio Iris Motta P. Métézeau S Brugère R. Perret

10.1016/0008-8749(82)90436-1

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Citations (5)

[Lanthanum and scorpion venom on the isolated guinea pig ileum].

PubMed (1975)

F Tazieff-Depierre Danièle Goudou P. Métézeau Prévot Ar

In the guinea-pig isolated ileum, lanthanum increases the quantity of spontaneously released acetylcholine and induces contracture of this muscle. We have shown that the latter phenomenon is not a consequence of the former. We conclude that it could be due to the Ca++ displaced by La+++. The scorpion venom effects are abolished by lanthanum. We explain this observation by blockage of Ca++ fluxes.

Lanthanum

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[Suppression of the spasmogenic action of scorpion venom isolated guinea pig ileum by an inhibitor of membrane permeability to calcium].

PubMed (1974)

F Tazieff-Depierre P. Métézeau Danièle Goudou

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ANTAGONISM OF THE PARALISIS PRODUCED BY BOTULINUM TOXIN IN THE FROG AND IN THE GUINEA-PIG BY TOXINS ISOLATED FROM SCORPION AND SEA ANEMONE VENOMS

Elsevier eBooks (1978)