H. Moriya

Research Field

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Effect of cooling rate and its interaction with pre-freeze and post-thaw tissue culture on the in vitro and in vivo function of cryopreserved pancreatic islets

Transplant International (1993)

J. Foreman H. Moriya Michael J. Taylor

Pancreatic Islets

Organ culture

10.1111/j.1432-2277.1993.tb00646.x

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Citations (13)

Two Cases of Segmental Aganglionosis of Colon by a Degenerative Disorder of Myenteric Plexus.

Nihon Daicho Komonbyo Gakkai Zasshi (1997)

Hisao Nakasaki H. Moriya Mineto Ohta Jinichi Soeda Hidehiro Tokunaga

症例1は63歳男性.6年前に多発性骨髄腫で2年間化学療法治療を受けた.同疾患の再発は認めず6年経過している.最近腹部膨満著明で高度の便秘を主訴として来院した.注腸造影で下降結腸の狭小化,内視鏡での拡張不全を認めるが粘膜面は異常所見を認めなかった.メコリール試験は陽性であった.症例2は56歳,女性.17年前に限局性巨大結腸症で脾屈曲部の大腸の拡張部位の切除を受けたが症状の改善を認めなかった.高度の便秘で来院した.注腸造影で異常な拡張から狭小への移行,内視鏡検査で拡張不全と粘膜面の正常所見,メコリール試験陽性,前回手術標本の再検討で狭小部のaganglionosisが証明された.症例1および2は狭窄部を含めて結腸切除が施行された.組織学的検索でlocalized segmental aganglionosisと診断された.術後の経過は4年および2.5年を経過しているが順調である.

Degenerative Disorder

Plexus

10.3862/jcoloproctology.50.45

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Prostaglandin E1-induced glucagon secretion under propranolol treatment in a case of idiopathic hyperglucagonemia.

PubMed (1982)

Ryushi Shimoyama Akio Hirayama H. Moriya

To see how prostaglandin E1 (PGE1) directly effects on the islet cells, PGE1 (200 ng/min) was infused into the celiac artery for 10 min in a patient with idiopathic hyperglucagonemia pretreated with propranolol (80 mg/day, for 5 days). Plasma immunoreactive glucagon (IRG), which had been suppressed to 568 pg/ml by the pretreatment, increased to 1,358 pg/ml at the end of infusion, and it remained over the basal value for 30 min. Plasma immunoreactive insulin (IRI) reached maximum at 5 min and decreased thereafter. These results suggest the possibility of the stimulatory effects of PGE1, not mediated by beta-adrenergic system, on glucagon secretion from alpha cells.

Hyperglucagonemia

Prostaglandin E1

Basal (medicine)

Phentolamine

Alpha (finance)

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Early fetal obstructive uropathy produces Potter's syndrome in the lamb

Journal of Pediatric Surgery (2000)

Hiroaki Kitagawa Kevin C. Pringle Jane Zuccollo Junki Koike Koonosuke Nakada

Obstructive uropathy