Theodore Ross

Women's College Hospital

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Practice parameters for the treatment of sigmoid diverticulitis—Supporting documentation

Diseases of the Colon & Rectum (2000)

Douglas W. Wong Steven D. Wexner Ann C. Lowry Anthony M. Vernava Marcus J. Burnstein

It should be recognized that these guidelines should not be deemed inclusive of all proper methods of care or exclusive of methods of care reasonably directed to obtaining the same results. The ultimate judgment regarding the propriety of any specific procedure must be made by the physician in light of all of the circumstances presented by the individual patient.

Diverticulitis

Colorectal Surgery

Surgical oncology

Patient Care

10.1007/bf02258291

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Citations (435)

Subcutaneous Heparin Versus Low-Molecular-Weight Heparin as Thromboprophylaxis in Patients Undergoing Colorectal Surgery

Annals of Surgery (2001)

Robin S. McLeod William Geerts Kenneth W. Sniderman Celia M.T. Greenwood Roger Grégoire

Objective To compare the effectiveness and safety of low-dose unfractionated heparin and a low-molecular-weight heparin as prophylaxis against venous thromboembolism after colorectal surgery. Methods In a multicenter, double-blind trial, patients undergoing resection of part or all of the colon or rectum were randomized to receive, by subcutaneous injection, either calcium heparin 5,000 units every 8 hours or enoxaparin 40 mg once daily (plus two additional saline injections). Deep vein thrombosis was assessed by routine bilateral contrast venography performed between postoperative day 5 and 9, or earlier if clinically suspected. Results Nine hundred thirty-six randomized patients completed the protocol and had an adequate outcome assessment. The venous thromboembolism rates were the same in both groups. There were no deaths from pulmonary embolism or bleeding complications. Although the proportion of all bleeding events in the enoxaparin group was significantly greater than in the low-dose heparin group, the rates of major bleeding and reoperation for bleeding were not significantly different. Conclusions Both heparin 5,000 units subcutaneously every 8 hours and enoxaparin 40 mg subcutaneously once daily provide highly effective and safe prophylaxis for patients undergoing colorectal surgery. However, given the current differences in cost, prophylaxis with low-dose heparin remains the preferred method at present.

Venography

Colorectal Surgery

10.1097/00000658-200103000-00020

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Citations (229)

Rectovaginal Fistulas and Intraoperative Bowel Injury

Springer eBooks (2007)

Theodore Ross Frederick D. Brenneman

Rectovaginal Fistula

Fecal Incontinence

Stoma (medicine)

Bowel preparation

10.1007/1-84628-238-1_44

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Citations (0)

Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure

Diseases of the Colon & Rectum (2000)

Carole Richard Roger Grégoire E. A. Plewes Ralph Silverman C J Burul

PURPOSE: This was a multicenter, randomized, controlled trial to compare the effectiveness of topical nitroglycerin with internal sphincterotomy in the treatment of chronic anal fissure. METHODS: Patients with symptomatic chronic anal fissures were randomly assigned to 0.25 percent nitroglycerin tid or internal sphincterotomy. Both groups received stool softeners and fiber supplements and were assessed at six weeks and six months. RESULTS: Ninety patients were accrued, but 8 were excluded from the analysis because they refused internal sphincterotomy after randomization (6), the fissure healed before surgery (1), or a fissure was not observed at surgery (1). There were 38 patients in the internal sphincterotomy group (22 males; mean age, 40.3 years) and 44 patients in the nitroglycerin group (15 males; mean age, 38.7 years). At six weeks 34 patients (89.5 percent) in the internal sphincterotomy group compared with 13 patients (29.5 percent) in the nitroglycerin group had complete healing of the fissure ( P=5 × 10−8). Five of the 13 patients in the nitroglycerin group relapsed, whereas none in the internal sphincterotomy group did. At six months fissures in 35 (92.1 percent) patients in the internal sphincterotomy group compared with 12 (27.2 percent) patients in the nitroglycerin group had healed ( P=3 × 10−9). One (2.6 percent) patient in the internal sphincterotomy group required further surgery for a superficial fistula compared with 20 (45.4 percent) patients in the nitroglycerin group who required an internal sphincterotomy ( P=9 × 10−6). Eleven (28.9 percent) patients in the internal sphincterotomy group developed side effects compared with 37 (84 percent) patients in the nitroglycerin group ( P<0.0001). Nine (20.5 percent) patients discontinued the nitroglycerin because of headaches (8) or a severe syncopal attack (1). CONCLUSIONS: Internal sphincterotomy is superior to topical nitroglycerin 0.25 percent in the treatment of chronic anal fissure, with a high rate of healing, few side effects, and low risk of early incontinence. Thus, internal sphincterotomy remains the treatment of choice for chronic anal fissure.

Anal fissure

Colorectal Surgery

10.1007/bf02236548

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Citations (192)

Inhibition of Coronavirus MHV-A59 Replication by Proteinase Inhibitors

Advances in experimental medicine and biology (1995)

Mark R. Denison James C. Kim Theodore Ross

Coronavirus

EIF4EBP1

10.1007/978-1-4615-1899-0_64

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Citations (7)

American Society of Colon and Rectal Surgeons 95th Annual Convention Podium and Poster Abstracts June 9-14, 1996 Seattle, Washington

Diseases of the Colon & Rectum (1996)

Daniel I. Obrand Gordon Gilbert Simone M. Rowley R H Grace S. Rai

American Society of Colon and Rectal Surgeons 95th Annual Convention Podium and Poster Abstracts June 9-14, 1996 Seattle, Washington: PDF Only

Colorectal Surgery

10.1007/bf02058726

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Citations (0)

Invited editorial

Diseases of the Colon & Rectum (2000)

Robin Phillips Robin S. McLeod Carole Richard Roger Grégoire E. A. Plewes

Phillips, Robin M.S., F.R.C.S.1; McLeod, R. S. M.D.2; Richard, C. S. M.D.3; Gregoire, R. M.D.4; Plewes, E. A. M.D.5; Silverman, R. M.D.6; Burul, C. M.D.7; Buie, D. M.D.8; Reznick, R. M.D.9; Ross, T. M.D.9; Burnstein, M. M.D.9; O'Connor, B. I. B.Sc.N.9; Mukraj, D.9 Author Information

10.1007/bf02236549

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Citations (0)

Rectovaginal fistula: initial experience.

PubMed (1988)

H. Štern Ziv Gamliel Theodore Ross Zeev Dreznik

Rectovaginal fistulas are not common, but the associated symptoms can be emotionally and physically disabling. The authors report their experience of 10 patients with a diagnosis of rectovaginal fistula, seen between December 1982 and July 1986. The women ranged in age from 28 to 74 years. All complained of passing feces or flatus, or both, through the vagina. In the majority of cases, fistulas were present for longer than 6 months before surgical repair. The fistulas were due mainly to trauma. Endorectal advancement flaps were used in seven patients with excellent results. Small fistulas due to obstetric trauma may heal spontaneously, so in these cases a 6-month waiting period before operation is recommended. However, fistulas due to inflammatory bowel disease will not heal spontaneously and should be repaired as soon as the patient's condition is optimal.

Rectovaginal Fistula

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Citations (8)

Ileal pouch vaginal fistulas

Diseases of the Colon & Rectum (1989)

Steven D. Wexner David A. Rothenberger Linda L. Jensen Stanley M. Goldberg Emmanuel G. Balcos

Some of the initial problems associated with the ileonal reservoir have been solved. In their place, other complications have been recognized. Among these, the ileal pouch vaginal fistula stands out as a recently recognized difficult management problem. This multicenter study was undertaken to gain insight into the causes for, and treatment of, pouch vaginal fistulas. Cases were gathered from 11 surgical practices, throughout North America, in which the ileoanal reservoir procedure is frequently performed. Overall, 304 females had undergone ileoanal reservoir procedures by these surgical groups. Twenty-one patients developed 22 pouch vaginal fistulas for an overall incidence of 6.9 percent. Five additional patients with pouch vaginal fistulas, whose restorative proctocolectomies were done elsewhere, were referred to these surgeons for treatment. The courses of these 26 patients form the basis of this report. This study details the risk factors which predispose to the development of a pouch vaginal fistula, as well as the various treatment options available.

Pouch

Vaginal fistula

Proctocolectomy

Colorectal Surgery

Pouchitis

10.1007/bf02554497

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Citations (98)

Assessment of treatment for patients with primary ductal carcinoma in situ in the breast

Annals of Surgical Oncology (1998)

Edward B. Fish Judy‐Anne W. Chapman Naomi Miller Marilyn A. Link E Fishell

Lumpectomy

Surgical oncology

Univariate analysis

10.1007/bf02303484

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Citations (16)