Sinan Karadeniz

University of Health Sciences

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Orhan Gelişen

Zübeyde Hanim Maternity Hospital

Alı Haberal

Zübeyde Hanim Maternity Hospital

Ahmet Erol

Batman University

Caner Köse

Memorial Ankara Hospital

Tuğba Kınay

Sağlık Bilimleri Üniversitesi

Mehmet Metin Altay

Zübeyde Hanim Maternity Hospital

Metin Altay

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi

Metin Kaplan

Fırat University

Funda Akpınar

Sağlık Bilimleri Üniversitesi

Tuğba Küçükkasap Cömert

Sağlık Bilimleri Üniversitesi

Cooperative Institutions

Zübeyde Hanim Maternity Hospital

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi

Sağlık Bilimleri Üniversitesi

University of Health Sciences

Ministry of Health

Turkish Armed Forces

Military Medical Academy

Gülhane Askerî Tıp Akademisi

University of Health Science

Women’s Health Care

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Investigate the relationship between the microbiota awareness in first trimester and high risk pregnancy in Turkish women: cross-sectional study

BMC Pregnancy and Childbirth (2023)

Tuğba Küçükkasap Cömert Sinan Karadeniz Funda Akpınar

It is suggested that pregnancy risks may be related to microbial dysbiosis, and it is known that knowledge on this subject is reflected in behaviors. The purpose of this study was to investigate whether microbiota awareness in the first trimester of pregnancy is associated with pregnancy-related risks.Within the scope of the study, the microbiota awareness scale was administered to 426 individuals in the first trimester of pregnancy, and information on any diagnosis related to high-risk pregnancy, gestational age, birth weight, and birth height of the newborn was obtained from their file records.The mean total microbiota awareness score of individuals was 61.38 ± 11.00 (26.00-91.00). The microbiota awareness score (56.85 ± 11.65) was found to be lower in individuals diagnosed with high-risk pregnancy (p < 0.05) than in healthy subjects (63.64 ± 9.94). Moreover, in individuals with high-risk pregnancies, a positive correlation was found between the microbiota awareness score and newborn birth weight and height (p < 0.05).The poor microbiota awareness level in pregnant women is associated with high-risk pregnancy and neonatal growth status.

Dysbiosis

High risk pregnancy

Cross-sectional study

10.1186/s12884-023-06121-3

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Citations (1)

Results of fetal anomaly screening performed at 11–14 weeks of gestation at a tertiary center

Perinatal Journal (2016)

Tuğba Kınay Metin Kaplan Mehmet Metin Altay Şafak Özdemirci Sinan Karadeniz

Center (category theory)

Tertiary care

10.2399/prn.16.0242010

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Citations (2)

Smooth muscle fraction of the round ligament in women with pelvic organ prolapse: a computer-based morphometric analysis

International Urogynecology Journal (2004)

Özlem Özdeğirmenci Yıldırım Karslıoğlu Suat Dede Sinan Karadeniz Alı Haberal

Uterine prolapse

Masson's trichrome stain

Trichrome

Uterosacral ligament

10.1007/s00192-004-1215-z

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Citations (35)

The Predictive Value of Systemic Inflammation Markers for the Success of Labor Induction with Foley Catheter

Türk Kadın Sağlığı ve Neonatoloji Dergisi (2022)

Tuğba Kınay Şule Atalay Mert Caner Köse Sinan Karadeniz Yaprak Engin Üstün

Amaç: Sistemik inflamasyon belirteçlerinin foley kateter ile doğum indüksiyonu başarısını öngörmedeki değerini araştırmak. Gereç ve Yöntem: Retrospektif kohort çalışmaya foley kateter ile doğum indüksiyonu uygulanan ≥ 37 hafta, tek, canlı, verteks geliş olan düşük riskli gebeler dahil edildi. Doğum indüksiyonu sonrası sezaryen ile doğumun gerçekleşmesi indüksiyon başarısızlığı olarak kabul edildi. Çalışma popülasyonu doğum indüksiyonu sonrası vajinal doğum yapanlar ve sezaryen doğum yapanlar olarak iki gruba ayrıldı. İki grubun demografik ve klinik özellikleri, prepartum tam kan sayımı değerleri, nötrofil/lenfosit oranı ve platelet/lenfosit oranı karşılaştırıldı. Bulgular: Çalışmaya toplam 308 gebe dahil edildi. Olguların 159’unda (%51,6) doğum indüksiyonu sonrası vajinal yolla doğum gerçekleşirken, 149’unda (%48,4) sezaryen doğum ile gebelik sonlandı. Nulliparite oranı sezaryen ile doğum yapan olgularda (%68,5) vajinal yolla doğum yapanlara (%54,1) göre daha yüksek bulundu (p=0,01). Vajinal yolla doğum yapan ve sezaryen doğum gereksinimi olan olguların lökosit sayıları (9804,9 ± 3283,4 h/mm3’e karşı 10437,1 ± 4439,8 h/mm3), nötrofil/lenfosit oranı (4,7 ± 4,1’e karşı 4,4 ± 3,9) ve trombosit/lenfosit (149,3 ± 67,0’e karşı 139,3 ± 50,1) oranı arasında istatistiksel olarak anlamlı bir fark saptanmadı (p>0,05). Sonuç: Doğum indüksiyonu öncesi bakılan sistemik inflamasyon belirteçleri ile doğum indüksiyon başarısı arasında anlamlı ilişki bulunmadı. Bununla birlikte nulliparitenin foley kateter ile doğum indüksiyon başarısızlığı için bir risk faktörü olduğu saptandı.

Foley catheter

10.46969/ezh.1096673

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Vajinal kubbe prolapsusu olgularında abdominal sakrokolpopeksi

Sinan Karadeniz Ahmet Akın Sivaslıoğlu Levent Seçkin M. Metin Altay Evrim Ebru Kovalak

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Normal Gebelik ve Preeklampside Baseline Serum ve Serebrospinal Sıvı Magnezyum Düzeyleri

Turkiye Klinikleri Journal of Gynecology and Obstetrics (1997)

Ömer Altun Orhan Gelişen Zekeriya Saçma Sinan Karadeniz Günnur Altun

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The relation between delivery type and cord blood levels of chitotriosidase and Troponin T

Open Medicine (2010)

Turan Tunç Erkan Demirkaya Mustafa Kul Halıl Yaman Sinan Karadeniz

Abstract The operative deliveries can expose the fetus to acute and systemic hypoxia along with an increase in perinatal morbidity. The aim of this study was to reveal any relationship between delivery type and Chitotriosidase and Troponin T levels in cord blood. Ninety babies born in Ankara Etlik Maternity and Women’s Health Teaching Hospital were involved in the study. The babies were divided into three groups; Group 1: Normal vaginal; Group 2: Caesarean section; Group 3: Forceps application. Cord blood samples were drawn from umbilical arteries of the babies soon after the birth. Chitotriosidase enzyme activities in group 3 (141 nmol/ml/h (0–246)) were found higher than groups 1 (100 nmol/ml/h (0–208)) and 2 (91 nmol/ml/h (0–202)) (p<0.01 and p<0.03 respectively). Although cardiac Troponin T levels were higher in group 3, the difference among groups was not statistically significant (p=0.79). Acute or systemic hypoxic exposure of the organism gives rise to a microvascular response characterized by interactions between leukocytes and endothelium. We are hypothesizing that the high levels of chitotriosidase found in the forceps group were due to hypoxia, and that chitotriosidase level can be used as a marker of acute and systemic hypoxia.

Cord blood

Hypoxia

10.2478/s11536-010-0016-7

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Reliability of the urine spot test in predicting urinary tract infections during pregnancy: a cross-sectional study

Türk Kadın Sağlığı ve Neonatoloji Dergisi (2023)

Kübra Dilbaz Elif Ece ÖZTÜRK ÖZEN Sinan Karadeniz

Background: The aim of this study was to investigate whether there is a significant difference in positive uronalysis (Total UA) results and fertility in urine cultures during pregnancy. Material and Methods: Our retrospective observational study included 177 patients who were admitted to our hospital between September 1, 2023 and November 1, 2023 and had a complete urinalysis performed. As a result of the total UA, patients with leukocytes/bacteria> 5, leukocyte esterase positive and nitrite positive were identified. Among the patients whose urine culture was detected according to the results of urinalysis, those whose urine culture was evaluated and those who were not were divided into two groups. The results of total UA and urine culture were compared. In addition, the weeks of gestation of patients with positive urinalysis results were recorded and it was investigated whether there was a correlation between the frequency of urinary tract infections (UTI) and pregnancy. Results: A total of 177 patients who were followed up for pregnancy were included in the study. All patients had total UA results. When the total UA abnormalities were examined, it was found that the rate of those with a high leukocyte/bacteria ratio was 80.2%, the rate of those with positive leukocyte esterase was 61%, and the rate of those who were nitrite positive was 25.4%. According to the urine culture results, 54.8% of participants had no urine culture and 45.2% of participants had one. The rate of urine cultures was 77.5% without reproduction and 22.5% with reproduction. In addition, the mean gestational weeks of the patients was 25.96±11.57 weeks, the mean week of gestation according to ultrasound measurements was 26.02±11.64. and no significant association was found between weeks of gestation and the incidence of UTI. Conclusion: In our study, no significant association was found between positive total UA results during pregnancy and urine culture reproduction. There is a need for comprehensive multicenter studies with a larger number of patients regarding the incidence of UTIs in relation to gestational age and other tests that can be used in the diagnosis of UTIs.

Leukocyte esterase

10.46969/ezh.1402089

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Citations (1)

Normal Gebelik ve Preeklampside Gama Glutamil Transferaz ve Fibronektin Aktivitesinin Karşılaştırılması

Turkiye Klinikleri Journal of Gynecology and Obstetrics (1997)

Ömer Altun Oskar Öğüten Orhan Gelişen Sinan Karadeniz Hakan Güralp

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Results of fetal anomaly screening performed at 11–14 weeks of gestation at a tertiary center

Perinatal Journal (2016)