Bone and joint infections such as osteomyelitis, septic arthritis, etc. are serious medical conditions that require prompt and effective treatment. Without proper intervention, these infections can lead to significant complications, including chronic pain, deformity, loss of function, and even systemic complications such as sepsis. Antibiotic therapy plays a k ey role in the management of these infections making it possible to prevent serious complications, preser ve limb function, reduce treatment costs, and improve clinical outcomes. The ar ticle discusses the basic principles and algorithms for antibacterial treatment of infection in the given localization, taking into account modern clinical recommendations and standards of pharmacotherapy. Timely diagno - sis and adequate treatment can reduce the risk of complications and improve the prognosis in patients with bone and joint infections. The rational use of antibiotics is also a par t of the fight against developing microbial resistance, which is of great importance for public health.
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