Background: We aim to directly compare the feasibility and safety of extended pelvic lymph node dissection (PLND) during transperitoneal robotic-assisted radical prostatectomy (Tp-RARP) and extraperitoneal laparoscopic radical prostatectomy (Ep-LRP). Materials and Methods: We retrospectively identified the prospectively maintained database records of 162 patients diagnosed with prostate cancer (PC) who underwent Ep-LRP or Tp-RARP with extended PLND. Patients with risk of nodal metastases over 5% according to Briganti nomogram received extended PLND. All data analyzed in this study were based on the documentation in our PC database including age, body mass index, Charlson comorbidity index score, preoperative prostate-specific antigen, history of abdominal surgery, biopsy Gleason score, total operation time, postoperative pelvic drainage time, pathological results, lymph node yield (LNY), percentage lymph node involvement (%LNI), and perioperative complications. Patients were followed up for biochemical recurrence in the postoperative period. Results: Eighty-two of the 162 enrolled patients were in group 1 (Ep-LRP+PLND) and 80 were in group 2 (Tp-RARP+PLND). There were no statistically significant differences between the groups regarding preoperative demographics and clinical characteristics. The median LNY was 17 (range 8-27) and 17.5 (range 10-29) in groups 1 and 2, respectively, and no statistically significant difference was found. There was no significant difference between the groups in terms of biochemical recurrence-free survival with mean follow-up of 44.8 months after radical surgery. Conclusion: Our results support the view that extended PLND through the Ep-LRP approach is a feasible and safe procedure without compromising oncological efficacy compared with a similar template attempted during Tp-RARP. Clinical Trial Registration number is 01/21-2.
Periferik arter psodoanevrizmasi oldukca nadir gorulen bir komplikasyon olup siklikla atesli silah vekesici delici aletle yaralanma veya invaziv vaskuler girisimler sonrasinda gelismektedir. Periferik arterpsodoanevrizmasinin tedavisinde geleneksel yaklasim cerrahi onarim olup primer sutur, otojen veyasentetik greftlerle hazirlanan yamalar kullanilmaktadir. Kesici delici alet yaralanma oykusu olan veyaklasik bir ay sonra fark edilen sag tibialis anterior arter yaralanmasina ait psodoanevrizma gelisenolguda cerrahi tedavi yontemini degerlendirdik
Background: Increased intra-abdominal pressure (IAP) in patients admitted to the intensive care unit leads to reduced abdominal perfusion pressure (APP), causing circulatory insufficiency and organ failure. Aims:To investigate the effect of maintaining a targeted APP on renal injury and the effect of increased IAP on the mortality rate in patients with septic shock. Study Design: Randomized, controlled, open-label study.Methods: A total of 72 patients were randomly divided into two groups (MAP65 or APP60).The MAP target for patients in the MAP65 group (n = 36) was 65 mmHg according to the Surviving Sepsis Guidelines.In the APP60 group (n = 36), the target APP was set to > 60 mmHg.The glomerular filtration rate (GFR), inotrope consumption, and IAP were recorded daily.The need for renal replacement therapy, decrease in GFR, and 30-and 90-day mortality rates were compared between the two groups.Results: In both the groups, the IAP was statistically similar (p = 0.458).The decreased in GFR was similar in both groups during the first 2 days.From day 3, there was a more statistically significant rapid decline in GFR in the MAP65 group than in the APP60 group.The GFR p-values on the 3 rd , 4 th , and 5 th days were 0.040, 0.043, and 0.032, respectively.Eight patients (22.2%) in the MAP65 group and three patients (8.3%) in the APP group required renal replacement therapy (p = 0.101).The 30-day mortality rates in the MAP65 and APP60 groups were 61.1%, and 47.7%, respectively (p = 0.237).The 90-day mortality rates in the MAP65 and APP60 groups were 66.7% and 66.7%, respectively (p = 1).Conclusion: Setting an APP target limited the reduction in GFR.The mortality rates were similar in the two groups and there was no difference in the rate of end-stage renal failure between the groups.
Purpose: Major vascular injuries, which are life threatening, may occur during laparoscopic procedures.1 The aim of this video is to illustrate the key points to avoid complications and to manage them during renal vein dissection. Method: Three cases are presented in the video; right transperitoneal laparoscopic nephrectomy of a 59-year-old male patient for a nonfunctioning kidney related to renal stone disease, laparoscopic right retroperitoneal radical nephrectomy of a 59-year-old male patient for a 3.5 cm renal mass, and laparoscopic left transperitoneal radical nephrectomy of a 63-year-old male patient for a 5 cm renal mass, respectively. All procedures were completed laparoscopically. The operation time was 220, 130, 190 minutes, respectively, and the estimated blood loss was 110, 25, 125 cc, respectively. Patients were discharged after removal of drain on the 3rd day of surgery. Results: In the first case, the Hem-o-lok® clip applicator injured the renal vein during clip placing on the renal artery. Bleeding was decreased by traction of the renal vein, but the surgeon was unable to place clips on the artery and vein together. Thereafter, Hem-o-lok clips were placed on the artery and vein separately. In the second case, inadequate dissection of the renal artery caused difficulties to place the Hem-o-lok clip. Because the tip of the clip was placed on the junction of the renal vein, segmental vein, and vena cava inferior (VCI), more dissection of the renal artery was performed and a second clip was placed under the first one. In the last case, the tip of the metal clip injured the renal vein while placing the clip on the adrenal vein. Bleeding was decreased by traction of the renal vein and the Hem-o-lok clip was placed on the proximal side. Retrograde bleeding due to an unsecured renal artery was controlled by placing the metal clips on the distal side of the renal vein. Afterward, the Hem-o-lok clips were placed on the renal artery. Conclusion: Complete and clear identification of the renal vein, the artery with their branches and delicate dissection of renal hilum should be performed. The locking tip of the Hem-o-lok clip must be clearly visualized at the back of the vessel before closure to avoid injuries. The renal vein can be injured easily by a part of sharp instruments like the tip of a clip applicator especially when applicator removal after clip placement as it was shown in the first case. In the second case, tissue at the clicking point of the Hem-o-lok clip may cause displacement. Therefore, it was mandatory to place a second secure clip proximal to first one even it is close to VCI. At the third case, adequate dissection of the renal vein and its branches should be performed. In case of any bleeding, adequate traction of the renal vein and increasing the abdominal pressure may decrease bleeding, until obtaining a reliable clip placement. To ensure correct clip placement during bleeding, suction from an additional port should be used for providing better visualization in the surgical area. No competing financial interests exist. Runtime of video: 8 mins 30 secs
To describe a novel surgical technique, laparoscopic stepwise-cut double initial stay suture (LASDISS) pyeloplasty for ureteropelvic junction obstruction (UPJO). Additionally, we evaluated the safety and short-term results.This was a nonrandomized study with a series of 6 patients with UPJO, operated on between March 2012 and August 2013. Perioperative and short-term outcomes were evaluated. In brief, a "T shape cut" was performed from the dilated pelvis to the ureter. The initial stay suture was placed between the lower edge of the pelvis and the distal end of the spatulated anterolateral part of the ureter. The pelvis was closed with a continuous suture starting from the opened upper edge of the pelvis that was secured after leaving enough space for ureteral anastomosis. The second initial stay suture was placed after passing the ureter and pelvis two times. The dilated part of the renal pelvis and the stenotic segment were excised. A double-J stent was inserted. The remaining space between the two initial sutures was closed with these continuous sutures.We performed the LASDISS pyeloplasty technique in all cases. Median operation time was 177 minutes (range, 100-290 minutes). Mean follow-up was 7.5 months (range, 3-18 months). The mean pre- and postoperative split renal function on diuretic renography was 33% (range, 25%-56%) and 42% (range, 30%-52%), respectively.The LASDISS pyeloplasty surgical technique represents a safe and effective option in surgical treatment of UPJO.
Tubo-ovarian abscess in the third trimester of pregnancy is extremely rare. In this report, an unusual case with asymptomatic tubo-ovarian abscess, diagnosed incidentally during Cesarean section performed for an obstetric indication, is presented. Unlike other reported cases, no signs or symptoms attributable to pelvic abscess throughout the pregnancy were observed in our patient. To our knowledge, this is the first report of such a case in the literature.