e21692 Background: SC is considered as valuable supportive therapy combined with CTX. The aim of the study was to judge and increase the efficacy basing on standardized and objective parameters (trichogram,HMI analysis via trichometry). Methods: 40 patients with breast cancer received (neo)adjuvant EC-Taxol regimes, optionally combined with SC. 8 patients out of this group opted against SC (control group). Pre- (T0) and post-therapeutically (T1) crownhair density was documented via trichometer, a trichogram was created, the diameter of hairbulbus and shaft was determined, and the association of HMI with general medical factors was investigated too. Results: HMI declined for all SC patients in median from 80 to 55 , for the control group from 76 to 5; divergence and T1 data showed significant differences (U-Test p < 0,001). In 20 SC patients (63%) no visible hairloss was found and only6 out of 12 SC patients with visible effluvium decided for a head cover. Complete hairloss was seen in the control group. A strong correlation of HMI with diameter of hair shaft (Spearman-correlation, R = 0,580; p < 0,001), bulbus (R 0 0,317; p = 0,077) as well as anagen rate (R = 0,436; p = 0,013) was seen. Patients in premenopausal status had a significant greater shaft diameter in T0 and T1 as patients in postmenopausal status (U-Test, p = 0,038 and p = 0,022). Patients with systemic comorbidities, regular medication and postmenopausal status showed a significant lower anagen rate in T0 compared to patients without these conditions (U-Test, p = 0,012; p = 0,003, p = 0,010). We found a strong correlation between HMI and psychological strain (Kendal-Correlation T = -0,386, p = 0,005; t = -0,502, p < 0,001) as well as contentment (t = 0,556, p < 0,001; t = 0,399, p = 0,003). The EORTC QLQ C30 survey indicated a significant higher quality of life and impressive positive emotional status for all SC patients compared to the control group (U-Test, p < 0,001, p = 0,012). Conclusions: All SC patients showed significant better trichological hair results, an impressive higher quality of life and less psychological strain compared to the control group. In future, selected factors might allow a predictive statement on the success of SC in advance.
Background/Aim: Osteotomy as the first step in surgery, provides access to the field and its application could influence the outcome. Nowadays, the conventional burr reduction is being challenged by newer sonic and ultrasonic methods. We investigated the bone structural integrity and metal attrition residues both in bone and the irrigation fluid. Materials and Methods: Bovine ribs were cut using three methods. Bone cuts were studied using Environmental Scanning Electron Microscopy (ESEM) for tissue discrepancies and Scanning Electron Microscopy/Energy Dispersion X-Ray Microanalysis (SEM/EDX) for organic and inorganic debris. Results: Better preservation of bone architecture was seen in piezo and sono surgery while metal attrition was not conclusive (p>0.05). Unlike in bone analyses, both bur and ultrasonic osteotomies showed statistically significant higher median inorganic detection per analysis (p=0.021 and p=0.037, respectively). Conclusion: Sono and piezo surgery proved to be less invasive while attrition properties were the same.
Se describe el caso de un quiste globulomaxilar que rodea circularmente la raiz del incisivo lateral, que por su topografia simula el cuadro clinico de un quiste periodontal. Se discute tanto cerca de la etiologia y la patogenia como acerca de la entidad nosologica de dicho quiste.
(Quintessenz 1996; 47: 897-908)
