Lin Feng

Second Military Medical University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Yun‐Heng Shen

Second Military Medical University

Weidong Zhang

Second Military Medical University

Xian‐Wen Yang

Hainan Medical University

Sumei Li

Guangdong Provincial Hospital of Traditional Chinese Medicine

Jun‐Mian Tian

Northwest A&F University

Xiaohua Liu

Sichuan University

Hua‐Wu Zeng

Second Military Medical University

Yong‐Li Li

Zhejiang Normal University

Ning Wang

Xinjiang Academy of Agricultural Sciences

Yonghong Liu

Chinese Academy of Sciences

Cooperative Institutions

Second Military Medical University

Chinese Academy of Sciences

Shanghai Jiao Tong University

Institute of Oceanology

Shanghai University

King Saud University

Northwest A&F University

Sichuan University

Central South University

Kunming Institute of Botany

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Chemical Constituents ofDracocephalum forrestii

Planta Medica (2009)

Sumei Li Xian‐Wen Yang Yong‐Li Li Yun‐Heng Shen Lin Feng

A systematic phytochemical examination of the whole plant Dracocephalum forrestii led to the isolation of 4 new and 65 known chemical constituents. By detailed 1D and 2D NMR spectroscopic analyses, the new compounds were identified as 4-hydroxy-3-methoxyphenylethanol 8- O-[(6- O-syringoyl)- beta- D-glucopyranoside] (1), 3,4,5-trimethoxyphenylethanol beta- D-glucopyranoside ( 2), 4- O-[ beta- D-glucopyranosyl-(1 --> 3)- alpha- L-rhamnopyranosyl]phenylethylcinnamamide (3), and 9''- O- N-butyl lithospermate (4). The new isolates were evaluated for inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. Compound 2 revealed a moderate effect without any cytotoxicity under the assayed concentrations.

Phytochemical

10.1055/s-0029-1185868

Cite

Citations (27)

Crystal structure of (E)-ethyl 2-(2-(2-(2,4-dinitrophenyl)hydrazono)-2- phenylethyl)-2,5-dimethyl-7-phenylbenzo[d][1,3]dioxole-4-carboxylate, C32H27N4O8

Zeitschrift für Kristallographie - New Crystal Structures (2013)

Qiang Wang Yun-Chang Fan Lin Feng Yun Li

Abstract C 32 H 27 N 4 O 8 , triclinic, P 1̅ (no. 2), a = 10.085(2) Å, b = 11.302(2) Å, c = 13.269(3) Å, α = 80.76(3)°, β = 78.81(3)°, γ = 82.30(3)°, V = 1456.1 Å 3 , Z = 2, R gt (F) = 0.0691, wR ref (F 2 ) = 0.1756, T = 293 K.

Triclinic crystal system

Carboxylate

Dinitrophenyl

Crystal (programming language)

10.1524/ncrs.2013.0162

Cite

Citations (0)

ChemInform Abstract: Abiesanordines A—N: Fourteen New Norditerpenes from Abies georgei

ChemInform (2008)

Xian‐Wen Yang Sumei Li Lin Feng Yun‐Heng Shen Jun‐Mian Tian

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.200839184

Cite

Citations (0)

Abiesanol A, a novel biflavanol with unique six connective hexacyclic rings isolated from Abies georgei

Tetrahedron Letters (2008)

Xian‐Wen Yang Sumei Li Lin Feng Yun‐Heng Shen Jun‐Mian Tian

10.1016/j.tetlet.2008.03.065

Cite

Citations (30)

Abiesatrines A–J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr

Organic & Biomolecular Chemistry (2010)

Xian‐Wen Yang Sumei Li Liang Ping Wu Yong‐Li Li Lin Feng

A novel spiro-lanostane (abiesatrine A, 1) was isolated from the aerial parts of Abies georgei together with 9 new (abiesatrines B–J, 2–10) and 10 known triterpenes (11–20). The new structures were established by the extensive analysis of their spectroscopic data. The configuration of 1, featuring a unique spirolactone formed by C-13 and C-23 via oxygen-bridge, was confirmed by X-ray crystallography, and its biopathway was tentatively proposed. Among these isolates, compound 16 showed the strongest inhibitory activity against LPS-induced NO production in RAW264.7 macrophages (IC50 = 8.9 μg mL−1). While compounds 1 and 20 exhibited potent anti-proliferative effects on QGY-7703 cells with IC50 values of 9.3 and 7.6 μg mL−1, respectively. Preliminary structure–activity relationship (SAR) investigations defined structural feature of the 24Z-olefinic bond key to the lanostane and cycloartane pharmacophore.

Lanostane

Terpene

10.1039/c001885f

Cite

Citations (52)

Chemical constituents of Aeschynanthus bracteatus and their weak anti-inflammatory activities

Phytochemistry (2008)

Sumei Li Xian‐Wen Yang Yun‐Heng Shen Lin Feng Yue‐Hu Wang

Anti-inflammatory

10.1016/j.phytochem.2008.05.012

Cite

Citations (28)

Chemical constituents of Abies delavayi

Phytochemistry (2014)

Xian‐Wen Yang Sumei Li Yong‐Li Li Lin Feng Yun‐Heng Shen

Imperatorin

Bergapten

Phytochemical

Terpene

10.1016/j.phytochem.2014.05.012

Cite

Citations (27)

Mono- and Sesquiterpenoids, Flavonoids, Lignans, and Other Miscellaneous Compounds ofAbies georgei

Planta Medica (2010)

Xian‐Wen Yang Yong‐Li Li Sumei Li Yun‐Heng Shen Jun‐Mian Tian

A systematic phytochemical investigation of the aerial parts of Abies georgei yielded nine new and 72 known compounds, including four monoterpenes, four sesquiterpenes, 25 flavonones, 14 lignans, and 34 other chemical constituents. The new compounds included two monoterpenes (1 and 2), two sesquiterpenes (3 and 4), three flavonones (5, 6, and 7), and two other components (8 and 9). Their chemical structures were established on the basis of various spectroscopic data. All the isolates were tested for antitumor and anti-inflammatory activities. The new compound 9,4'-dihydroxy-5,7-dimethoxy-8-methylchalcone (7) demonstrated a moderate antiproliferative effect on QGY-7703 tumor cells (IC (50) = 17.6 µg/mL). The known compound isoferulaldehyde (67) exhibited the strongest inhibitory activity against lipopolysaccharide (LPS)-induced NO production in RAW 264.7 macrophages (IC (50) = 19.0 µg/mL). Abies georgei may be a significant source of beneficial pharmaceutical compounds.

Phytochemical

10.1055/s-0030-1250550

Cite

Citations (18)

Isolation, structure, and bioactivities of abiesadines A–Y, 25 new diterpenes from Abies georgei Orr

Bioorganic & Medicinal Chemistry (2009)

Xian‐Wen Yang Lin Feng Sumei Li Xiaohua Liu Yong‐Li Li

Abietane

10.1016/j.bmc.2009.11.055

Cite

Citations (86)

Abiesanordines A–N: fourteen new norditerpenes from Abies georgei