Padma S. Menon

KPJ Ampang Puteri Specialist Hospital

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Nalini S. Shah

C. U. Shah University

Tushar Bandgar

King Edward Memorial Hospital and Seth G.S. Medical College

Raju A. Gopal

Apollo Hospitals

Shrikrishna V. Acharya

K S Hegde Medical Academy

Anurag Lila

King Edward Memorial Hospital and Seth G.S. Medical College

Vijaya Sarathi

Institute of Medical Sciences

Joe George

Christie's

Vyankatesh Shivane

College of Medicine & JNM Hospital

Hosahithlu K. Ganesh

Institute of Medical Sciences

Abhay Dalvi

King Edward Memorial Hospital and Seth G.S. Medical College

Cooperative Institutions

King Edward Memorial Hospital and Seth G.S. Medical College

College of Medicine & JNM Hospital

King Edward Memorial Hospital Research Centre

Creative Commons

Tata Memorial Hospital

Endocrinology Research Center

Collaborative Group (United States)

Institute of Medical Sciences

Jawaharlal Institute of Post Graduate Medical Education and Research

Lilavati Hospital & Research Centre

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Neonatal Central Hypothyroidism Due to Uncontrolled Maternal Thyrotoxicosis

The Endocrinologist (2009)

Raju A. Gopal Shrikrishna V. Acharya Tushar Bandgar Padma S. Menon Nalini S. Shah

Central hypothyroidism in neonates born to mothers with uncontrolled thyrotoxicosis is uncommon. We describe the case of an infant born with clinical and biochemical central hypothyroidism to a mother who had severe uncontrolled thyrotoxicosis. The neonate was treated with thyroxine and improved clinically. It is important to anticipate this neonatal complication to institute early treatment to avoid motor and mental developmental delay.

Congenital hypothyroidism

Central hypothyroidism

10.1097/ten.0b013e3181acb20e

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Citations (0)

An Unusual Variant of Cushing Syndrome

Endocrine Practice (2008)

Hosahithlu K. Ganesh Joe George Mavila V. Vimal Tushar Bandgar Padma S. Menon

Cushing's disease

Bilateral adrenalectomy

Cushing Disease

10.4158/ep.14.6.717

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Citations (4)

Laparoscopic Transmesocolic Excision of Paraganglioma in the Organ of Zuckerkandl

Journal of Laparoendoscopic & Advanced Surgical Techniques (2006)

Pinky M. Thapar Abhay Dalvi Ranjeet Kamble V. Vijaykumar Nalini S. Shah

Extra-adrenal pheochromocytomas (paragangliomas) are rare. We report the case of a 20-year-old female at 15 weeks gestation, who was detected to have a large paraganglioma (6.5 × 5 cm) in the organ of Zuckerkandl during an antenatal visit. After medical termination of the pregnancy, successful laparoscopic excision of the paraganglioma was performed.

10.1089/lap.2006.16.620

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Citations (14)

Correlation of number of intrathyroid lymphocytes with antimicrosomal antibody titer in Hashimoto's thyroiditis

Diagnostic Cytopathology (2003)

Ajita Pandit Maya Vijay Warde Padma S. Menon

The variants of Hashimoto's thyroiditis (classic, florid, and fibrotic types) differ in clinical manifestations, laboratory tests, and morphology. The titers of autoantibodies correlate with the degree of thyroidal lymphocytic infiltration (Wislon et al., 1998(5)) It appears that the density of lymphocytes is inversely proportional to antimicrosomal antibody (AMA) titer. The aim of the present study is to determine the precise relationship between the number of lymphocytes and AMA titer. It may be useful to predict the onset of the disease in subclinically hypothyroid patients. In 62 cases of cytologically confirmed Hashimoto's thyroiditis, the number of lymphocytes per high-power field was counted and correlated with AMA titer. The grading of lymphocytes was done as 1 (<10/HPF), 2 (11-20/HPF), and 3 (>/=21/HPF). The results showed no correlation between lymphocyte number and AMA titer.

Anti-thyroid autoantibodies

Lymphocytic infiltration

10.1002/dc.10235

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Citations (28)

Remission in Cushing disease with cabergoline

Annals of Saudi Medicine (2008)

Raju A. Gopal Tushar Bandgar Padma S. Menon Nalini S. Shah

Cabergoline

Cushing's disease

Lipodystrophy

Craniopharyngioma

10.5144/0256-4947.2008.224

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Citations (5)

Inferior petrosal sinus sampling in the diagnostic evaluation of Cushing's syndrome: K.E.M. experience.

PubMed (2005)

A M Kalgikar S A Chandratreya Atul Goel Mayank Shrivastava Uday Limaye

An overlap in the clinical and biochemical features of the more common pituitary Cushing's disease and the rare ectopic ACTH secreting tumors often leads to a diagnostic dilemma. High quality computed imaging modalities have a poor sensitivity and do not always help in localising the tumor. Inferior petrosal sinus sampling (IPSS) with measurement of ACTH levels localizes the source of excess ACTH secretion and aids in the differential diagnosis of ACTH dependant Cushing's syndrome.To analyze the efficacy of inferior petrosal sinus sampling in the basal state and its role in the diagnostic evaluation in patients of Cushing's syndrome.Forty four patients of proven Cushing's syndrome underwent HDDS and pituitary imaging followed by IPSS (unstimulated). The data was analysed in 39 patients with definite histopathological diagnosis which included 34 patients with Cushing's disease, four with ectopic Cushing's syndrome and one with adrenal carcinoma. A centre:periphery ratio of plasma ACTH levels of > or =2 was considered diagnostic of Cushing's disease.Cannulation rate was 100%. No neurological complications were encountered. IPSS could correctly localize the lesion in 23 of 34 patients of Cushing's disease (sensitivity: 67.6%). All patients of ectopic Cushing's syndrome and adrenal carcinoma had a ratio of <2 (specificity: 100%). IPSS helped in localization of the lesion and improved the diagnostic yield from 26.7% to 73.5%.IPSS helps in localization in patients of Cushing's syndrome with a diagnostic dilemma and should be carried out only in centers with suitable expertise.

Inferior petrosal sinus

Cushing's disease

Cushing Disease

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Citations (6)

Has experience changed the scenario in laparoscopic adrenalectomy?

Indian Journal of Surgery (2009)

Abhay Dalvi Pinky M. Thapar Nalini S. Shah Padma S. Menon

Endocrine surgery

Cardiothoracic surgery

10.1007/s12262-009-0021-8