Salah M. Elsayed

Benha University

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Effect of Combined Administration of Ginger and Cinnamon on High Fat Diet induced Hyperlipidemia in Rats

Salah M. Elsayed Reham A. Moustafa

The present study was performed to further elucidate the hypolipidemic action of combined administration of ginger and cinnamon for their effects on the diet-induced hyperlipidemia in rats. It has been reported that plasma cholesterol and triglyceride concentrations decrease when animals are fed with mixture of ginger and cinnamon in 1% and 2% administration. Rats were fed cholesterol- free diet, (negative control), cholesterol-enriched diet and 5% of lard for 6 weeks. The study investigated the effects of combined administration of ginger and cinnamon at 1% and 2% adding on diet on triglyceride , total cholesterol, HDL-C and VLDL-C + LDL-C levels behinds effect of combined administration on AST and ALT enzymes , total protein and albumin concentrations . The results showed that combination of ginger and cinnamon could decrease levels of triglyceride (TG), total cholesterol (TC), very low density lipoprotein cholesterol + low density lipoprotein cholesterol (vLDL-C + LDL-C) and increase (HDL-C) in plasma (p<0.05). In addition ginger and cinnamon mixture decrease levels of AST and ALT enzymes but the level of total protein and albumin in plasma was unchanged (p<0.05). Keyword: Ginger; cinnamon; triglycerides; cholesterol

Hyperlipidemia

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Protective role of Ascophyllum nodosum seaweed biomass conjugated organic minerals as therapeutic nutrients to enhance tomato plant grown under salinity stress

Biomass Conversion and Biorefinery (2023)

Mohamed S. Attia Amer M. Abdelaziz Salah M. Elsayed M. Osman M. Ali

Abstract Climate changes and stresses negatively affected the physiological processes inside plant cells, which led to a clear imbalance in the global diet. In both irrigated and non-irrigated areas, salinity is one of the principal abiotic factors influencing plant growth and production, especially in crop plants. The present experiment was designed to evaluate two types of foliar feeding as anti-salt stress by measuring stress tolerant and antioxidant levels. Foliar feedings, Gluamin Cu, and Ascophyllum nodosum (WeGrow Special) were used as therabutic nutrients and stress raisers on plants irrigated with saline solution (150 mmol) and others irrigated with tap water. After 70 days of plant life, morphological characteristics, plant pigments, osmosis levels, phenols, and antioxidant enzyme activity were measured as indicators of plant recovery from stress damage. Measurements of vegetative growth, photosynthesis, sugars, and protein content decreased significantly in stressed plants. On the contrary, the level of proline, phenol, malondialdehyde, hydrogen peroxide, and sodium (Na + ) and the activity of antioxidant enzymes increased compared to non-stressed plants. The beneficial impacts of the foliar feedings (Gluamin Cu and WeGrow Special) have been broadened to increase all growth parameters, photosynthetic pigments, proline, phenol, and enzyme activities, in both unstressed and stressed plants in comparison to control. Interestingly, the harmful impact of salinity on tomato plants was significantly decreased and it can be evident from reduced MDA and H 2 O 2 levels. The results indicated that Gluamin Cu at a concentration of 3 cm L −1 foliar was the best treatment in increasing shoot length by 18.75%, root length by 51.8%, number of leaves by 31.5%, chlorophyll A by 98.9% and chlorophyll B by 47.6%, proline 12.6%, peroxidase by 39.6%, polyphenol oxidase by 14.29%, super oxide dismutase by 16.4%, and catalase by 54.9% in stressed plants compared to the stressed control. These results indicated that the use of any of the foliar nutrients (Gluamin Cu and WeGrow Special) considered to raise the salt stress in the plant and improve its morphological characteristics and metabolic processes inside the cells, and thus it can be used and applied commercially as environmentally friendly anti-salt stress.

Ascophyllum

10.1007/s13399-023-05103-x

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Hepatoprotective Effects of Moringa Oleifera Seeds Against Ethanol Induced Liver Damage In Wistar Rats

chemistry and materials research (2016)

Salah M. Elsayed Reham A. Moustafa

Hepatocytes are reportedly susceptible to the injurious effects of oxidants when exposed to toxic substances such as Ethanol . The widespread claims of the medicinal efficacy of various parts of Moringa oleifera plant have been well documented in literature. Oil was extracted from seeds and acetone extract was prepared from defatted seeds and evaluate antioxidant properties. The in vitro antioxidant of oil and acetone extract of Moringa oleifera (M. oleifera) seeds were assayed by DPPH scavenging activity and reducing power. The in vivo hepatoprotective effects evaluated in male Wistar rats against ethanol induced liver damage in preventive and curative models. The M. oleifera oil and acetone extract (300 mg/kg body weight (bw), and silymarin (100 mg/kg bw) were administered orally in both the studies. Liver injury was induced by 40% ethanol administration (3.76 gm/kg bw, orally) for 30 days. Both moringa oil and acetone extract showed a good amount of phenols and flavonoids and appeared antioxidant activity in reducing power and DPPH scavenging activity assay, while the oil of moringa was the more effective one compared with acetone extract. The level of plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) , total bilirubin , albumin, total protein and plasma antioxidant state (MDA content and catalase activity) were determined to assay hepatotoxicity. Ethanol administration caused severe hepatic damage in rats as evidenced by elevated plasma AST, ALT, ALP , total bilirubin, albumin, , total protein , MDA content and catalase activity levels. The oil , acetone extract of M. oleifera and silymarin administration prevented the toxic effect of ethanol on the above plasma parameters in preventive model. The present study concludes that oil and acetone extract of M. oleifera seeds have significant antioxidant and hepatoprotective activity against ethanol induced hepatotoxicity. Key words: Moringa oil , Moringa acetone extract, ethanol, antioxidant, liver,.

Moringa

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Wuxal amino (Bio stimulant) improved growth and physiological performance of tomato plants under salinity stress through adaptive mechanisms and antioxidant potential

Saudi Journal of Biological Sciences (2021)

M. Ali Kaouthar Jeddi Mohamed S. Attia Salah M. Elsayed Mohammad Yusuf

In the present study, ameliorative capabilities of wuxal amino (bio stimulant) under salt stress has been investigated through adaptive mechanisms and antioxidant potential in tomato plants. In the experiment, two different concentrations (2 cm L-1 and 3 cm L-1) of wuxal amino through foliar application and soil irrigation were applied to the salt (150 mM) treated tomato plants and then morphological traits, photosynthetic pigments, osmolytes, secondary metabolites, oxidative stress and antioxidant enzymes activity were assessed at 60 days after planting. The results revealed that salt stress decreased the growth parameters, photosynthetic pigments, soluble sugars and soluble protein whereas, content of proline, ascorbic acid, total phenols, malondialdehyde, hydrogen peroxide and the activity of antioxidant enzymes activity increased under salt stress. Moreover, Wuxal amino application through foliar or soil to salt stressed plants improved morphological traits, photosynthetic pigments, osmolytes, total phenol and antioxidant enzymes activity. Interestingly, the deleterious impact of salinity on tomato plants were significantly reduced and it can be evident from reduced MDA and H2O2 levels. These responses varied with the mode (foliar or soil) of application of Wuxal amino under different concentrations (2 cm L-1 and 3 cm L-1). It was concluded that application of Wuxal amino (2 cm L-1, foliar) and (3 cm L-1; soil) proved best and could be commercially used as eco-friendly tool for the protection of tomato plants grown under salinity stress.

Osmolyte

Malondialdehyde

10.1016/j.sjbs.2021.04.040

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Role of calcium and magnesium on dramatic physiological and anatomical responses in tomato plants

Notulae Botanicae Horti Agrobotanici Cluj-Napoca (2022)

Ayshah Aysh ALrashidi Haifa A. S. Alhaithloul Mona H. Soliman Mohamed S. Attia Salah M. Elsayed

Minerals are the fundamental source of nutrients for plant functions such as photosynthesis, ATP currency, cellular respiration, metabolic activities, defense mechanisms, and tolerance to biotic and abiotic stressors. Minerals are the most significant component of plant nutrition and applying these minerals supplements can increase fruit output. The study’s main aim was to make agricultural farming easier by foliar applying newly created nutrients like Lebosol-calcium and Magnesium. The four treatments: To (Control), T1 (Lebosol-Mg-Plus, 3 ml/L), T2 (Lebosol-Ca-Forte, 3 ml/L), and T3 (Lebosol-Mg-Plus and Lebosol-Ca-Forte, 3 ml/L) was applied as foliar spray to the seedlings of tomato. It was found that T3 substantially enhanced tomato’s morphological features and yield. The treatment T3 significantly increased total soluble protein, chlorophyll content, and antioxidant enzyme activity. Furthermore, the foliar application of T3 considerably improved phenolic and ascorbic acid contents. The general anatomical features of the leaf, stem, and roots of tomato were qualitatively affected by the treatments. Application of Lebosol-Ca provided the highest total thickness of lamina, number of vessel elements, total phloem area, chlorenchyma layer, total area of vessel elements, xylem ratio, and increased palisade layer thickness, vessel diameter. Furthermore, T3 treatment showed a diverse impact on the internal structure of tomato organs, with palisade and spongy parenchyma growing to maximum values and vessel diameters expanding. T3 had also posed remarkable alterations in morpho-physiological, biochemical, and anatomical aspects in tested plants.

10.15835/nbha50112614

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Federated learning model for credit card fraud detection with data balancing techniques

Neural Computing and Applications (2024)

Mustafa Abdul Salam Khaled M. Fouad Doaa L. El-Bably Salah M. Elsayed

Abstract In recent years, credit card transaction fraud has resulted in massive losses for both consumers and banks. Subsequently, both cardholders and banks need a strong fraud detection system to reduce cardholder losses. Credit card fraud detection (CCFD) is an important method of fraud prevention. However, there are many challenges in developing an ideal fraud detection system for banks. First off, due to data security and privacy concerns, various banks and other financial institutions are typically not permitted to exchange their transaction datasets. These issues make traditional systems find it difficult to learn and detect fraud depictions. Therefore, this paper proposes federated learning for CCFD over different frameworks (TensorFlow federated, PyTorch). Second, there is a significant imbalance in credit card transactions across all banks, with a small percentage of fraudulent transactions outweighing the majority of valid ones. In order to demonstrate the urgent need for a comprehensive investigation of class imbalance management techniques to develop a powerful model to identify fraudulent transactions, the dataset must be balanced. In order to address the issue of class imbalance, this study also seeks to give a comparative analysis of several individual and hybrid resampling techniques. In several experimental studies, the effectiveness of various resampling techniques in combination with classification approaches has been compared. In this study, it is found that the hybrid resampling methods perform well for machine learning classification models compared to deep learning classification models. The experimental results show that the best accuracy for the Random Forest (RF); Logistic Regression; K-Nearest Neighbors (KNN); Decision Tree (DT), and Gaussian Naive Bayes (NB) classifiers are 99,99%; 94,61%; 99.96%; 99,98%, and 91,47%, respectively. The comparative results show that the RF outperforms with high performance parameters (accuracy, recall, precision and f score) better than NB; RF; DT and KNN. RF achieve the minimum loss values with all resampling techniques, and the results, when utilizing the proposed models on the entire skewed dataset, achieved preferable outcomes to the unbalanced dataset. Furthermore, the PyTorch framework achieves higher prediction accuracy for the federated learning model than the TensorFlow federated framework but with more computational time.

Credit card fraud

Resampling

10.1007/s00521-023-09410-2

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Potential impacts of Ascophyllum nodosum, Arthrospira platensis extracts and calcium phosphite as therapeutic nutrients for enhancing immune response in pepper plant against Fusarium wilt disease

Biomass Conversion and Biorefinery (2023)

Mohamed S. Attia Salah M. Elsayed Amer M. Abdelaziz M. Ali

Abstract The search for active inducers against diseases in the formula of therapeutic nutrients has become a necessity for many researchers. The study’s chief purpose was to make agronomic farming simpler by applying newly created therapeutic nutrients. The novelty of this research is the applied of algal extracts in adding to minerals as therapeutic nutrion. Calcium (Maxifos Ca), Ascophyllum nodosum (Greencal), and Arthrospira platensis ( A. platensis ), were tested for induction pepper plant resistance against Fusarium wilt. The disease index (DI), morphological growth, photosynthetic pigments, free proline, total phenol, hydrogen peroxide (H 2 O 2 ), malondialdehyde (MDA), and antioxidant enzymes as reactions to the induction of protection in challenged tested plants were measured. Results revealed that the use of entirely different treatments significantly minimized the danger of Fusarium wilt. Treatment of infected plants with Maxifos Ca was the best treatment, as it reduced the DI to 25% and thus reduced symptoms and improved the percentage of plant protection from the disease by 69.6%. Surprisingly, it was widely assumed that Greencal was the greatest treatment for restoring vegetative growth, followed by Maxifos Ca and an algal extract, A. platensis . The application of Greencal, followed by Maxifos Ca, and then A. platensis significantly increased the expression of all metabolic resistance indices (phenols, polyphenol oxidase, and peroxidase). The best treatments for reducing the signs of stress represented in (MDA and H 2 O 2 ) were Maxifos Ca and then Greencal. According to the findings the use of Maxifos Ca, Greencal, and A. platensis as alternate therapeutic nutrients of eco-destructive chemically synthesized fungicides appears to be a significant methodology for reducing the harmful effects of Fusarium wilt on pepper plants.

Ascophyllum

Malondialdehyde

10.1007/s13399-023-03949-9

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Citations (23)