J.P. Lepoutre

Recent diagnostic criteria for progressive supranuclear palsy (PSP) by the Movement Disorder Society (MDS) operationalise recently recognised subtypes, beyond the ‘classical’ Richardson phenotype (PSP-RS): predominant parkinsonism (PSP-P), predominant gait freezing (PSP-PGF), and frontal-cognitive- behavioural presentations (PSP-F).

Aims

To evaluate the proportion of patients fulfilling MDS compared with previous NINDS-SPSP criteria; to establish the number of patients fulfilling operationalised subtypes criteria; and to explore the evolution of PSP subtypes.

Methods

A retrospective case note review study of 201 patients clinically diagnosed with PSP in a combined behavioural neurology and movement disorders service over a 10-year period.

Results

Of 201 patients at first presentation, 187 met MDS-PSP criteria (157 probable, 8 possible, 22 sug- gestive) compared with 152 for NINDS-SPSP criteria. The number of probable PSP patients fulfilling opera- tionalised subtype criteria were: 125 PSP-RS, 111 PSP-P, 5 PSP-PGF, and 37 PSP-F. Notably, 100 patients met criteria for more than one subtype.

Conclusion

MDS criteria allowed earlier PSP diagnosis than NINDS-SPSP criteria and captured a range of phenotypic subtypes. Further analysis will address the issue of determining subtype predominance and will explore the natural history of PSP phenotypes, with particular reference to frontal-cognitive- behavioural presentations.

10.5344/ajev.2002.53.1.64

Cite

Citations (36)

Aroma Composition of a White Wine of Vitis vinifera L. cv. Emir as Affected by Skin Contact

Journal of Food Science (1997)

Turgut Cabaroğlu Ahmet Canbaş Raymond Baumes Claude Bayonove J.P. Lepoutre

ABSTRACT Free and glycosidically bound flavor compounds of a white wine from cv. Emir were analyzed by GC‐MS, and 75 compounds were identified. The wine was high in volatile phenols. Skin‐contact with the juice before fermentation increased amounts of free and glycosidically bound flavor compounds. Quantities of certain compounds were significantly different between control and skin‐contact wines.

White Wine

Aroma of wine

Fermentation in winemaking

Wine color

10.1111/j.1365-2621.1997.tb15434.x

Cite

Citations (67)

Influence de traitements phytosanitaires sur le potentiel aromatique de la baie de muscat et des vins correspondants

HAL (Le Centre pour la Communication Scientifique Directe) (1996)

C. Aubert Raymond Baumes Z. Gunata J.P. Lepoutre J.F. Cooper

Source

Cite