Norimichi Watanabe

Shinshu University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Katsuhiro Okamoto

National Research Institute of Police Science

Yasuaki Hagimoto

National Research Institute of Police Science

Norio Hayashi

Gunma Prefectural College of Health Sciences

Hiroki Miyamoto

Sendai Seiyo Gakuin College

Hideo Ohtani

Tokyo Metropolitan Tama-Hokubu Medical Center

Kaoru Wakatsuki

Kobe City Medical Center General Hospital

Masakatsu Honma

National Research Institute of Police Science

Muneyuki Hiramatsu

Yamanashi Prefectural University

Koji Miwa

Tokyo Metropolitan Police Department

Goro Kikuchi

Ibaraki University

Cooperative Institutions

Tohoku University

University of Tsukuba

Shinshu University

Ōtani University

The University of Tokyo

National Research Institute of Police Science

Nagoya University

Kyoto University

Tokyo Metropolitan Police Department

National Institute of Mental Health

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

[Spontaneous differentiation from myeloperoxidase-negative acute nonlymphocytic leukemia to acute myelomonocytic leukemia].

PubMed (1989)

Norimichi Watanabe H Hamaguchi Minoru Yoshida Takaya Suzuki Kazunori Watanabe

We reported a 68-year-old woman with acute nonlymphocytic leukemia, in whom the leukemia transformed from poorly differentiated myeloperoxidase (MPO)-negative type into myelomonocytic type during the observation without chemotherapy. Hematological findings on admission revealed a leukocyte count of 3,500/microliters with 48% blasts and a platelet count of 9.2 x 10(4)/microliters. Bone marrow aspiration showed 68.2% infiltration of blasts negative for MPO. Sudan black B and esterase stains. By electron microscopy MPO was detected in the endoplasmic reticulum and nucleoenvelope of the blasts. Large vacuole-like granules were MPO-negative. She was observed without administration of any antileukemic agent or an immunopotentiator. The leukocyte count rose gradually, in association with increases in the relative and absolute counts of mature neutrophils and monocytic cells, and the platelet count. Twenty-six months after the initial diagnosis, a blood examination showed a leukocyte count of 74,300/microliters with 20.5% mature neutrophils and 15.5% monocytic and a platelet count of 31.4 x 10(4)/microliters. Cytological, cytochemical, ultrastructural and immunological studies of the bone marrow cells showed features compatible with acute myelomonocytic leukemia (FAB M4). This case is unusual in respect that poorly differentiated ANLL transformed spontaneously into moderately differentiated ANLL.

Acute myelomonocytic leukemia

Acute monocytic leukemia

Sudan Black B

Absolute neutrophil count

Source

Cite

Citations (0)

Evaluation of Thermal Protection of Japanese Firefighter Helmet and its Improvement to Thermal Insulation

Journal of Textile Engineering (2017)

Ryutaro SEITA Kaoru Wakatsuki Norimichi Watanabe Limin Bao Hideaki Morikawa

A Firefighter helmet plays an important role to protect the firefighter’s head from falling object, falls from a height and heat and flame from fire and heated smoke within a structure. A Japanese firefighter helmet is very light and comfort during their operation relative to Europe and North-America, but has problem in heat resistance of shock absorption material such as polystyrene foam because it is polymeric. Therefore, protection of polystyrene foam from heat has very important role in terms of both skin burns on head and shock protection by object and fall. The objective of this paper is to build up the test instrument on firefighter helmet against heat, investigate the thermal resistance on current Japanese firefighter helmet. Then, a method by covering the polystyrene foam by cellulose fiber wipes was proposed and investigated its performance by number of layers of the wipes. It has been found that both installation of cellulose fiber wipes between helmet shell and polystyrene foam has insulated heat to polystyrene foam and absorption of water by the cellulose fiber wipes which released from aluminum hydrate as fire retardant for firefighter helmet shell made time delay to increase the temperature and maintain the performance of heat insulation. It is expected that this installation of wipes has great effect to maintain shock absorption even if the helmet is exposed to heat and flame for firefighter working environment.

Polystyrene

Expanded polystyrene

Cellulose fiber

10.4188/jte.63.181

Cite

Citations (0)

Fire Hazard of Electric-battery-powered Vehicle in Terms of Burning Behaviour

火災 (2012)

Norimichi Watanabe

Fire hazard

Source

Cite

Citations (0)

Two chronic myelogenous leultaemia cell lines which represent different stages of erythroid differentiation

British Journal of Haematology (1993)

K. Endo Hideo Harigae Tadashi Nagai Hiromi Fujie Kuniaki Meguro

Summary We established two cell lines, YN‐1 and Y‐1K. from the peripheral blood of two chronic myelogenous leukaemia patients in blastic crisis. Characterization of the YN‐1 and Y‐1K cells revealed that these cells expressed erythroid lineage markers. However, there was a marked difference in the level of γ‐globin mRNA and haenioglobin in YN‐1 and Y‐1K cells. YN‐1 contained approximately 1–5% benzidine‐positive staining cells, whereas no benzidine‐positive cells were observed in Y‐1K cells. Haemoglobin production in YN‐1 cells was markedly increased with various chemical inducers of erythroid differentiation, but was not in Y‐1K cells. In contrast, Y‐1K cells expressed CD34 stem cell antigen and CD41 megakaryocyte‐specific antigen. These observations suggested that, although both cell lines were committed to the erythroid lineage. each cell line represented a distinct differentiation stage in the erythroid differentiation programme. Y‐1K seemed to correspond to an early stage of cells in erythroid lineage, whereas YN‐1 represented a more advanced stage in human erythropoiesis.

Lineage markers

K562 cells

Lineage (genetic)

Precursor cell

10.1111/j.1365-2141.1993.tb03205.x

Cite

Citations (35)

Changes in evaporation rate and vapor pressure of gasoline with progress of evaporation

Fire Safety Journal (2009)

Katsuhiro Okamoto Norimichi Watanabe Yasuaki Hagimoto Koji Miwa Hideo Ohtani

Fraction (chemistry)

Flash point

Mass fraction

Flash evaporation

10.1016/j.firesaf.2009.03.004

Cite

Citations (62)

Adherence to the standard dose of imatinib, rather than dose adjustment based on its plasma concentration, is critical to achieve a deep molecular response in patients with chronic myeloid leukemia Chikashi YoshidaTakuya KomenoMitsuo HoriTomofumi KimuraMasami FujiiYasushi Okoshi • Kazumi SuzukawaShigeru ChibaYuichi HasegawaHarumi Yamamoto MukaiTakayoshi Ito •

Chikashi Yoshida Takuya Komeno Mitsuo Hori Kimura M. Fujii Okoshi K. Suzukawa

The correlation between imatinib (IM) trough plasma concentration (Cmin) and clinical response was assessed in patients with chronic-phase chronic myeloid leukemia. The Cmin correlated with neither the achieve- ment of complete cytogenetic response (977 vs. 993 ng/ml, P = 0.48) nor a major molecular response (1,044 vs. 818 ng/ml, P = 0.17). Although this was significantly higher in patients with complete molecular response (CMR) than in those without (1,430 vs. 859 ng/ml, P = 0.04), the difference was not significant in the sub- population treated with a standard dose of IM (400 mg/ day). Finally, multivariate analysis showed that the IM standard dose, but not Cmin, was predictive of the achievement of CMR. We thus suggest that, in practical clinics at least, adherence to the standard dose is the most important factor for the achievement of CMR.

Cmin

Chronic myelogenous leukemia

Source

Cite

Citations (0)

Efficient Design Approach of Metallic Photonic Crystal Bandpass Filter using Off-Centered Post-Wall Irises for 5G Applications

IEICE Technical Report; IEICE Tech. Rep. (2020)

Erika Katsuno Chun‐Ping Chen Tetsuo Anada Tsuchiya Takenobu Norimichi Watanabe

Source

Cite

Citations (0)

Altered surface expression of effector cell molecules on neutrophils in myelodysplastic syndromes

British Journal of Haematology (1997)

Akimichi Ohsaka Katsu Saionji J Igari Norimichi Watanabe Kazuhisa Iwabuchi

The surface expression of effector cell molecules on neutrophils was examined in 18 patients with myelodysplastic syndromes (MDS) and 20 healthy control subjects. The MDS patients were further classified as low clinical risk (L-MDS, n=7) and high clinical risk (H-MDS, n=11). The expression of Fc receptors for IgG (FcR), complement receptors (CR) and cellular adhesion molecules on neutrophils was determined by flow cytometry and monoclonal antibodies. The effect of granulocyte colony-stimulating factor (G-CSF) and tumour necrosis factor-alpha (TNF) on L-selectin shedding and CR up-regulation on neutrophils was also examined. The percentage of FcRI-positive neutrophils and CD11b/CR3 expression on neutrophils were significantly increased in the H-MDS patients when compared to the controls. In contrast, the expression of FcRII, FcRIII, L-selectin, LFA-1 and CD18 on neutrophils was significantly reduced in the H-MDS patients compared with the controls. The L-MDS neutrophils exhibited lower expressions of CR1, L-selectin, LFA-1 and CD18 than those of the controls. Neutrophils from some H-MDS patients showed impaired L-selectin shedding and CR up-regulation after stimulation with G-CSF or TNF, although these were not significantly different when assessed in the whole H-MDS group. These findings suggest that an altered surface expression of effector cell molecules and an impaired modulation of cellular adhesion molecules on neutrophils may contribute to the increased susceptibility to bacterial infections in MDS patients.

L-selectin

10.1046/j.1365-2141.1997.1873007.x

Cite

Citations (34)

Relation of the extra-sequence of the precursor form of chicken liver δ-aminolevulinate synthase to its quaternary structure and catalytic properties

Archives of Biochemistry and Biophysics (1984)

Norimichi Watanabe Norio Hayashi Goro Kikuchi

Molecular mass

10.1016/0003-9861(84)90527-7

Cite

Citations (7)

[Improved technique on the thermal neutron depth distribution in tissue by the insertion of a pingpong-ball into the excised tumour cavity].