S Suzuki

Tokai University

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BRAIN STEM ENCEPHALITIS CAUSED BY HERPES SIMPLEX VIRUS TYPE 2

Journal of Neuropathology & Experimental Neurology (1987)

S Suzuki John R. Martin

10.1097/00005072-198705000-00042

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Effects of Benidipine Hydrochloride on Contractions Induced by Some Contractile Agents in Isolated Cerebral and Mesenteric Arteries of Dogs.

Biological and Pharmaceutical Bulletin (1995)

S Suzuki Takayuki Uegomori Sugako Ozaki Yasushi Takata H. Kato

The effects of benidipine on contractions induced by contractile agents were studied in isolated dog basilar, middle cerebral and mesenteric arteries and compared with those of nicardipine. KCl (20-80 mM), U-46619 (3 x 10(-10)-3 x 10(-6)M) and 5-hydroxytryptamine (5-HT) (10(-9)-3 x 10(-6)M) produced concentration-dependent contractions in the three arteries. Benidipine (10(-11)-8 x 10(-9)M) inhibited non-competitively the KCl-induced contraction in the basilar, middle cerebral and mesenteric arteries with a pD'2 of 9.1, 9.7 and 8.5, respectively. There was a significant difference between the pD'2 values in the cerebral and mesenteric arteries. Benidipine (10(-6)-3 x 10(-5)M) attenuated significantly the contraction produced by both U-46619 and 5-HT in the three arteries, the pD'2 being 4.4-4.9. Nicardipine inhibited the contraction induced by the three contractile agents in the same manner as benidipine. The contraction caused by 70 mM KCl in the cerebral and mesenteric arteries was reduced by 33-38 and 18%, respectively following treatment with 0.25 mM Ca2+ solution. Furthermore, pretreatment with a Ca(2+)-free solution containing 1 mM EGTA inhibited KCl-induced contractions in the basilar, middle cerebral and mesenteric arteries by 98.7, 95.6 and 92.1%, respectively. It also attenuated the contractions produced by both 10(-6) M U-46619 and 3 x 10(-6) M 5-HT in the cerebral and mesenteric arteries by 56-61 and 34-39%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

Nicardipine

Mesenteric arteries

EGTA

10.1248/bpb.18.507

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Citations (1)

Characterization of mouse natural killer cell activating factor (NKAF) induced by OK-432: Evidence for interferon- and interleukin 2-independent NK cell activation

British Journal of Cancer (1984)

Osamu Ichimura S Suzuki Yohei Sugawara T Osawa

Sephadex

Sepharose

10.1038/bjc.1984.144

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Citations (17)

Salt-sensitive aortic aneurysm and rupture in hypertensive transgenic mice that overproduce angiotensin II.

PubMed (1998)

Naomi Nishijo Fumihiro Sugiyama Katsuhiko Kimoto Keiko Taniguchi K Murakami

Atrial natriuretic peptide

Aortic rupture

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Citations (64)

A case of triple colon cancers with situs inversus totalis.

Nihon Daicho Komonbyo Gakkai Zasshi (1990)

Makoto Niizawa M. Itoh T Mukojima Mitsumasa Takeda Naoki Mizuguchi

われわれは内臓逆位に大腸三重重複癌を伴った1例を経験したので報告する.症例, 52歳, 女性.下腹部膨満感・下腹部痛を主訴に来院.内臓逆位の所見に加え, 注腸検査で下行結腸にapple-core sign, 横行結腸に陥凹性病変を認めたため, 大腸内視鏡検査を施行.下行結腸にほぼ全周性の2型の腫瘤を認め, 生検で中分化型腺癌を検出した.狭窄が高度なため, さらに口側への内視鏡挿入は不能であった.また腹部CT検査で, 内臓逆位の所見に加え, 肝S6に腫瘤を認めたが, 術前肝腫瘤の質的診断は困難であった.以上より内臓逆位・大腸重複癌・肝腫瘤と診断し, 切除術を施行.手術標本で下行結腸に2型と0型の陥凹性病変および横行結腸に0型の陥凹性病変を認め, 病理組織像で癌組織を確認した.また肝腫瘤は大腸癌の肝転移であった。内臓逆位に大腸癌を含む重複癌の報告は散見されるが, 大腸多発癌を合併した報告例はなく, われわれの症例はきわめて稀なものと思われた.

10.3862/jcoloproctology.43.641

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Problems Relating to Salvage Surgery for Esophageal Cancer

Nihon Kikan Shokudoka Gakkai Kaiho (2013)

Takanori Inose T. Miyazaki Kantaro Hara Daigo Ozawa Yukio Yokoyama

Salvage Surgery

Cancer surgery

10.2468/jbes.64.157

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Citations (0)

[Bronchial circulation and hemoptysis].

PubMed (1988)

Yasuharu Nakajima Yukio Sodemoto S Suzuki

Circulation (fluid dynamics)

Bronchial artery

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[Optic glioma in neonates--report of two cases].

PubMed (1988)

Akira Andoh Hiroki Ohkuma K Ebina S Suzuki

We report two cases of optic glioma in neonates, which is rare and only 3 similar cases can be found in the literature so far. Case #1 was a 55-day-old boy having been lethargic since around his 25th postnatal day. Case #2 was a 100-day-old girl having also been in the same condition as Case #1 since around her 50th postnatal day. The tumor in either patients seemed to have originated from chiasm or its vicinity and were too large to remove totally. Histopathological diagnosis of the tumor was fibrillary astrocytoma grade II in Case #1, and was anaplastic astrocytoma grade III in Case #2, both of which are different from the most popular pilocytic astrocytoma in so called infantile optic glioma. Now, 5 months and 4 years respectively after the operation, mental and somatical developmental retardations are already seen in either patients. Their functional prognosis seems to be poor.

Pilocytic astrocytoma

Optic chiasm

Anaplastic astrocytoma

Optic chiasma

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Citations (1)

An ultrastructural study of mitotic chondrocytes in the Swarm rat chondrosarcoma.

PubMed (1993)

Shunichi Shibata Mamoru Niikura S Suzuki Tatsuo Terashima Yoshimi Yamashita

The Swarm rat chondrosarcoma is a well established model system for the biochemical studies of cartilage proteoglycans. In this study, we observed the ultrastructure of mitotic chondrocytes in this tumor to confirm whether it is also useful as a morphological model system to examine the mitosis of chondrocytes. As a result, the mitotic chondrocytes in this tumor contained fairly prominent cell organelles, and the endoplasmic reticulum was mainly vacuolized and the Golgi stacks were replaced by the cluster of small vesicles during the later stage of the mitotic cycle. Although the cytoplasmic division began at the telophase, the cytoplasmic cleavage furrow was so narrow that dividing chondrocytes looked as if they were partitioned by a slit. These findings are almost consistent with the changes that occurred in the mitotic chondrocytes of the tibial growth plate, although the degree of disorganization in the Golgi apparatus is slightly different. Therefore, this tumor is useful as a convenient morphological model system to examine the mitosis of chondrocytes because of the facility for taking specimens.

Telophase

Organelle

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Citations (1)

V68 Transanal repair of rectovesical fistula after radical prostatectomy using the modified Latzko technique

European Urology Supplements (2013)

Teruhisa Nomura M. Kawaguchi Kenji Kayanuma S Suzuki Jiro Kobayashi

Rectal fistula

10.1016/s1569-9056(13)61651-6

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Citations (1)