A Hastillo

Virginia Commonwealth University

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Hess Ml

Virginia Commonwealth University

Lower Rr

Michael L. Hess

Virginia Commonwealth University

Richard R. Lower

University of Wisconsin–Madison

Timothy C. Wolfgang

Brigham and Women's Hospital

Glenn R. Barnhart

Swedish Medical Center

George W. Vetrovec

Virginia Commonwealth University

Thompson Ja

University of Cincinnati

Szabolcs Szentpetery

Hunter Holmes McGuire VA Medical Center

James A. Thompson

Texas A&M University

Cooperative Institutions

Virginia Commonwealth University Medical Center

Virginia Commonwealth University

University of Pittsburgh

University of Virginia

University Health System

Hunter Holmes McGuire VA Medical Center

University of Richmond

Children's Hospital of Richmond at VCU

United States Department of Veterans Affairs

Thomas Jefferson University Hospital

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INTERLEUKIN-1 BLOCKADE AMELIORATES LEFT VENTRICULAR REMODELING FOLLOWING ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION - THE VCU-ART PILOT STUDY

Journal of the American College of Cardiology (2010)

Antonio Abbate Michael C. Kontos John D. Grizzard Giuseppe Biondi‐Zoccai Benjamín W. Van Tassell

Ventricular remodeling

10.1016/s0735-1097(10)60952-7

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Citations (1)

Comparison of atrial contribution to cardiac hemodynamics in patients with normal and severely compromised cardiac function

Clinical Cardiology (1990)

Jhulan Mukharji Roger B. Rehr A Hastillo Jeremy Thompson Michael L. Hess

Abstract The importance of atrial contribution to cardiac function in patients with congestive heart failure is controversial. Ten patients with severe congestive failure (Group A) and 10 patients with normal ventricular function (Group B) were studied during atrial and ventricular pacing. Left ventricular ejection fraction, baseline pulmonary capillary wedge pressure, and baseline cardiac index were different between Group A and Group B patients: 22±10 vs. 65±11 (p<0.01); 21±5 vs. 8±4, (p<0.01); and 2.8±0.5 vs. 3.5±1.0 (p=0.05). Compared with atrial pacing, cardiac index decreased from 2.8±0.6 to 2.2±0.5 (p<O.01) in Group A and from 3.6±0.7 to 2.9±0.5 (p<0.01) in Group B, during ventricular pacing. Pulmonary capillary wedge pressure increased by similar amounts in both groups during ventricular pacing. The change in cardiac index, % change in cardiac index, and change in pulmonary capillary wedge pressure from atrial to ventricular pacing, were not different between Group A and Group B patients. By logistic regression analysis, no association was found between the % change in cardiac index and the following variables: left ventricular ejection fraction, left ventricular end‐diastolic volume, baseline pulmonary capillary wedge pressure, change in pulmonary capillary wedge pressure, and baseline cardiac index. The atrial contribution to resting steady‐state cardiac function is similar between patients with severe congestive failure and those with preserved ventricular function.

Pulmonary wedge pressure

Cardiac index

10.1002/clc.4960130910

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Citations (42)

Selection of patients for cardiac transplantation.

PubMed (1990)

A Hastillo Hess Ml

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Citations (4)

Management and long-term followup of outpatient care in the cardiac transplant recipient.

PubMed (1990)

Thompson Ja S Rider-Katz Hess Ml Alain Heroux A Hastillo

Successful long-term management of the cardiac transplant patient requires the concerted effort of the patient, the cardiac transplant team, and the primary care physician. The long-term management of these patients will continue to evolve as new immunosuppressive agents are used and new methods of surveillance for rejection are found. The long-term management is indeed one of the most exciting parts of the care of the transplant patient, especially when all those involved can watch the patient enter into a normal lifestyle.

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Abnormal left ventricular diastolic function during acute rejection of cardiac transplants

The American Journal of Cardiology (1982)

Walter Paulsen Norman M. Magid Kiran B. Sagar A Hastillo Michael W. Hess

Ventricular Function

Heart transplants

10.1016/0002-9149(82)92318-9

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Cyclosporine-induced pericardial effusion after cardiac transplantation

The American Journal of Cardiology (1987)

A Hastillo James A. Thompson Richard R. Lower Szabolcs Szentpetery Michael L. Hess

Ciclosporin

Cushingoid

10.1016/0002-9149(87)90889-7

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Citations (23)

Hypercholesterolemia in long-term survivors of heart transplantation: an early marker of accelerated coronary artery disease.

PubMed (1991)

David Eich Thompson Ja Ko Dj A Hastillo R Lower

Hyperlipidemia

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Citations (141)

Beta 2 microglobulin and the diagnosis of cardiac transplant rejection.

PubMed (1983)

Goldman Mh Richard W. Lippman Douglas M. Landwehr Szabolcs Szentpetery Timothy C. Wolfgang

Dans 75% des cas, les episodes de rejet apres transplantation cardiaque s'accompagnent d'une augmentation de la beta 2 microglobuline serique (et urinaire). Cette augmentation peut preceder les manifestations cliniques du rejet (revue de 20 episodes de rejet chez 10 malades)

Beta-2 microglobulin

BETA (programming language)

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Citations (6)

Cardiac transplantation--1980: The Medical College of Virginia program.

PubMed (1980)

A Hastillo Hess Ml Richardson Dw Lower Rr

Within the last three years, advances in the fields of cardiac surgery and immunology have established the value of cardiac transplantation for patients with irreversible myopathic disease. Long-distance donor procurement has increased the availability of the donor pool and made possible a more critical selection of donor hearts. The development of antithymocyte globulin and the concept of individual immune monitoring has decreased the incidence of acute rejection and the dosage of prednisone and azathioprine necessary to achieve optimal graft protection. These advances are reflected in the survival statistics. Since 1977, the three-month mortality rate has decreased to 40%, as compared to 77% from 1968 to 1976. Ptatients who are discharged from the hospital are currently demonstrating an 88% one-year survival rate and are functional class I-II status. We conclude that in properly selected patients, cardiac transplantation is a viable option for end-stage cardiomyopathic disease.

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Citations (6)

Serial hemodynamic and left ventricular function changes following intracoronary thrombolysis in acute myocardial infarction

The American Journal of Cardiology (1982)

Michael J. Cowley George W. Vetrovec A Hastillo

Ventricular Function

10.1016/0002-9149(82)92253-6

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Citations (1)