A 51-year-old man presented with isolated diffuse gingival hypertrophy, the diagnosis of a plasmocytoma being suspected after pathological and immunohistological examinations of a gingival biopsy (light chain lambda plasmocytes). The isolated nature of this diffuse gingival plasmocytoma was confirmed by biological tests and radiological investigations. The evolution of solitary plasmocytomas is variable, and while certain of these lesions remain isolated even after many years, other plasmocytomas, apparently local, are associated with myelomas which either become evident or may sometimes develop. The extremely rare nature of diffuse gingival locations of extra-osseous solitary plasmocytomas is confirmed by a review of the published literature. Studying histological sections by immunofluorescence enables the polyclonal or monoclonal nature of the plasmocytes to be established, this distinction being an important element in the prognosis.

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Repeated micro-CT of a mouse illustrates development of liver metastases 9, 12, 14, and 19 days after intrasplenic injection of MC38 colon tumor cells.

Boll Hanne Stefanie Nittka Fabian Doyon Michael Neumaier Alexander Marx

10.1371/journal.pone.0025692.g005

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[Gougerot-Sjögren syndrome in patients with sarcoidosis].

PubMed (1976)

J Turiaf Battesti Jp Rain Jd Fabien A. Basset A Marc

Three patients with eye and salivary dryness presenting the scintigraphic and histological features of Sjogren's syndrome and also suffering from sarcoïdosis, are reported. The authors stress the rarity of clinically indentifiable dry oculo-salivary syndromes whilst routine scintigraphy of the principle salivary glands using technetium 99 m often reveals altered salivary function. They consider that the primary feature in the development of this dry salivary syndrome consists of fibro-inflammatory lesions of the glandular interstitium, seen in specimens of the glands of the labial mucosae, which are sequelae of the initial sarcoid infiltration. They point out that Sjogren's syndrome occurring in relation with sarcoïdosis has certain special features. These include its appearance in relatively young subjects, the minimal symptoms, the non-essential presence of inflammatory signs and the absence of associated connective tissue disorder.

Sjögren syndrome

Dry mouth

Infiltration (HVAC)

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[Comparative data of labial gland biopsies and scintigraphy with technetium 99m of the principal salivary glands in sarcoidosis].

PubMed (1976)

J Turiaf Battesti Jp Rain Jd A Marc Fabien A. Basset

Technetium-99m

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Endoscopy - An Advancement in Sinus and Skull Base Surgery

Endoscopy (2013)

Rickul Varshney Faisal Zawawi A Marc Saul Frenkiel

Skull base and sinus surgery has evolved dramatically throughout the past century. It is not long ago that the maxillary sinus would principally be reached via an anterior ap‐ proach through the gingivobuccal sulcus of the oral cavity. The earliest days of endos‐ copy date back to the early 1900s, when Hirschmann used a modified cystoscope to examine the sinuses. Thereafter, modern endoscopy has seen advances not only in the types of endoscopes available, but also the types of interventions amenable to the endo‐ scopic approach.

Endoscopic sinus surgery

10.5772/52749

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