Pogozheva Av

Federal Research Centre of Nutrition and Biotechnology

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Samsonov Ma

Tutel'ian Va

Vasil'ev Av

Federal Research Centre of Nutrition and Biotechnology

Derbeneva Sa

Mal'tsev GIu

Baturin Ak

Federal Research Centre of Nutrition and Biotechnology

БК

Б.С. Каганов

Federal Research Centre of Nutrition and Biotechnology

Sorokina EIu

Federal Research Centre of Nutrition and Biotechnology

Miagkova Ma

Pokrovskaia Gr

Cooperative Institutions

Federal Research Centre of Nutrition and Biotechnology

Russian Academy of Sciences

Academy of Medical Sciences

Ministry of Health of the Russian Federation

Peoples' Friendship University of Russia

Sechenov University

Siberian State Medical University

Samara State Medical University

Institute of Pharmacology Russian Academy of Medical Sciences

Medical Radiological Research Center

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[The nutrition analysis of the patients with cardio-vascular diseases].

Denisova Nn Pogozheva Av Baturin Ak

Authors of article have recently analyzed the actual food intake from patients with cardiovascular diseases with the help of a new computer program, based on frequency method. It was found a disbalance of intake main food components in different groups of patients.

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[Experience of phytosterols' application in dietetic cardiovascular diseases].

Pogozheva Av Б.С. Каганов Derbeneva Sa Mal'tsev GIu Shpitonkov Mi

The investigation of influent of antiatherosclerotic diets with phytosterols on clinical and metabolic parameters in patients with cardiovascular diseases. Results of the study show that enrichment of a diets with phytosterols in patients with ischemic heart disease and hypertension improved clinic status, antropometric levels and lipid spectrum of blood. The research has shown, that the use in the treat-preventive purposes phytosterols is rather perspective.

Phytosterol

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[The system of multilevel diagnostics and corrections of nutrition status disorders in the patients with cardiovascular diseases].

PubMed (2009)

Pogozheva Av Derbeneva Sa Bogdanov Ar Б.С. Каганов

As is known, the pathology of cardiovascular systems depends on nutrition and occupies leading positions in structure general morbidity and mortality of the population of Russian Federation. The system of nutritional and medical aids--"Nutritest" and "Nutricor", represent the technology of diagnostics of infringements the status of nutrition, estimations of risk of development of cardiovascular diseases, and ways of their high-grade correction.

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[The study of polymorphism rs9939609 FTO gene in patients with overweight and obesity].

PubMed (2011)

Baturin Ak Pogozheva Av Sorokina EIu О. Н. Макурина Tutel'ian Va

In 94 persons living in the Moscow region, with a body mass index >25 kg/m2 were identified on the polymorphism rs9939609 FTO gene. The results showed that 83% of them were carriers of the mutant allele, and 43%--contained the mutant allele in the homozygous state. Carriers of the mutant allele rs9939609 FTO gene were distinguished by higher absolute and relative values of fat mass and triglycerides in serum.

FTO gene

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Citations (4)

[Effect of dietotherapy on thrombocyte lysosomal hydrolase activity in patients with hyperlipidemia and ischemic heart disease].

PubMed (1987)

Vasil'ev Av Meshcheriakova Va Pogozheva Av Shimanovskaia Np Samsonov Ma

Hyperlipidemia

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[Effects of antiatherosclerosis diet including soy protein on the dynamics of clinical, biochemical and immunologic indicators in patients with ischemic heart disease and hypertension].

PubMed (1999)

Pogozheva Av Kondakova Mn Pokrovskaia Gr Mal'tsev GIu

Investigation of influence of diet with soy-protein on clinical and immune indices in patients with ischemic heart disease and hypertension was conducted. As a result of the diet modified by the protein component positive effect on the course of the diseases and lipid spectrum of blood, pronounced action on some indices of humoral immunity, intensity of processes of lipid peroxidation were observed.

Humoral immunity

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Citations (1)

[Use of phytoestrogens in medicine].

PubMed (2003)

Tutel'ian Va Pavliuchkova Ms Pogozheva Av Derbeneva Sa

In this review present big group of natural biology activity substances--flavonoids, and also products of soybean as main sours of phytoestrogens. Discussion preventive and medical role and potential ways of use phytoestrogens in died of patients with different diseases.

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[The study of the clinical potency of antiatherogenic diet containing flavonoids in cardiovascular patients].

PubMed (2003)

Lysikova Sl Pogozheva Av Akol'zina Se Vasil'ev Av Vorob'eva LSh

At 60 patients with coronary artery disease and high blood pressure studied effects of a diet with low lipid and flavons. The application of a diet and flavons promoted positive dynamics (changes) of clinical manifestations of disease, lipid spectrum and antioxidants.

Lipid Profile

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[The study of the association of polymorphism rs659366 gene UCP2 c obesity and type 2 diabetes among residents of the Moscow Region].

PubMed (2015)

Baturin Ak Sorokina EIu Pogozheva Av Peskova Ev О. Н. Макурина

1112 people from Moscow region have been surveyed. Genotyping of rs659366 polymorphism UCP2 gene was performed using allele-specific amplification, result detection in real time and using TaqMan-probes complementary DNA polymorphic sites. The study of rs659366 polymorphism of the UCP2 gene has showed that 36.9% of patients had genotype AA, 46.7%--genotype AG, and 16.5%--genotype GG. The frequency of allele A was 60.2%, allele G--39.8%. BMI, value of fat mass, visceral fat area, serum glucose and triglyceride levels were significantly higher in carriers of A allele in the homozygous and heterozygous state than in carriers of G allele in the homozygous state. Frequency of A allele compared with G allele in obese patients (BMI greater than 30 kg/m2) was: OR--1.52; CI (1.24-1.86), p = 0.001, and in diabetes mellitus type 2--OR--1.22; CI (0.910-1.622), p = 0.19.

TaqMan

Gene polymorphism

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Citations (2)

[Clinico-biochemical validation of the use of PUFA omega-3 in patients with ischemic heart disease, familial hyperlipoproteinemias and hypertension].

PubMed (1996)

Pogozheva Av Samsonov Ma Levachev Mm

The effectivity of diet AI, containing 20 g of fish oil eiconol, for patients suffering with ischemic heart disease, family hyperlipidemia and hypertension were checked. It was concluded that treatment with eiconol is recommended during 4 weeks 2-3 times per year in dose of 3-6 capsules 3 times a day depending on degree of lipids metabolism and hemocoagulation disturbances.

Hyperlipidemia

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