P. Amruta Reddy

Indian Institute of Technology Mandi

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Douglas F. Covey

Washington University in St. Louis

Steven M. Rothman

SUNY Upstate Medical University

C. David Gutsche

Texas Christian University

Matthew W. Hill

Brigham Young University

James A. Ferrendelli

The University of Texas Health Science Center at Houston

A. B. MANDAL

Indian Institute of Science Bangalore

Karen E. Woodward

The University of Texas Health Science Center at Houston

Tammy Latifi

Washington University in St. Louis

B. Rajasekhar

Dr. Reddy's Laboratories (India)

B. C. H. HSIANG

Washington University in St. Louis

Cooperative Institutions

Washington University in St. Louis

Indian Institute of Science Bangalore

Texas Christian University

The University of Texas Health Science Center at Houston

St. Louis Children's Hospital

University of Miami

The University of Texas at Austin

University of Missouri–St. Louis

Sri Venkateswara University

University of Minnesota

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ChemInform Abstract: Synthesis and Anticonvulsant Activities of 3,3‐Dialkyl‐ and 3‐Alkyl‐3‐ benzyl‐2‐piperidinones (δ‐Valerolactams) and Hexahydro‐2H‐azepin‐ 2‐ones (.epsilon.‐Caprolactams).

ChemInform (1997)

P. Amruta Reddy Karen E. Woodward Sarah M. McIlheran B. C. H. HSIANG Tammy Latifi

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.199717133

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ChemInform Abstract: A Novel Phase‐Transfer Catalyzed Cycloaddition of Carbonyl‐Stabilized Sulfur Ylides to Vinylic Sulfones.

ChemInform (1987)

D. B. REDDY P. S. REDDY B. V. Reddy P. Amruta Reddy

Abstract The arylcyclopropylsulfones (III) are prepared from the vinylic sulfones (I) by coupling with sulfur ylides derived from the phenacylsulfonium bromides (II).

10.1002/chin.198722171

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Inhibition of Voltage-Dependent Sodium Channels by the Anticonvulsant γ-Aminobutyric Acid Type A Receptor Modulator, 3-Benzyl-3-Ethyl-2-Piperidinone

Journal of Pharmacology and Experimental Therapeutics (1998)

Matthew W. Hill P. Amruta Reddy Douglas F. Covey Steven M. Rothman

Aminobutyric acid

10.1016/s0022-3565(24)37522-6

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Citations (1)

Combinatorial Syntheses of Polyhydroxamate Siderophores: Desferrioxamine, Exochelin, Mycobactin, and Aerobactin Libraries

Springer eBooks (2001)

Urszula Słomczyńska P. Amruta Reddy Otto F. Schall Todd A. Osiek Arati Naik

Aerobactin

Ferric ion

10.1007/978-94-010-0464-0_79

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Citations (2)

Sodium Binding Effects on Conformational Exchange in a Diquinone Calix[4]arene

Journal of the American Chemical Society (1997)

Marielle Gómez‐Kaifer P. Amruta Reddy C. David Gutsche Luis Echegoyen

NMR studies show that a 2,4-diethoxycalix[4]arene-1,3-diquinone undergoes an unusually slow conformational change, from a predominantly anti-aryl conformation to that of a syn-aryl conformation, in the presence of Na+ ion. Dramatic changes are observed throughout the entire NMR spectral region. A novel finding is that the timescale of this conversion is unusually long, taking many hours at room temperature to complete. The kinetics of this conformational change over the range of 5−55 °C were measured in a binary solvent system. The rate constants are on the order of 10-5−10-4 s-1 in the presence or absence of Na+. These results suggest a cation effect on the equilibrium position of the anti and syn complexes rather than on the rate of interconversion. The kinetics of interconversion in the presence and absence of the salt are the same. The rate determining step corresponds to rotation of an aryl moiety through the annulus of the calixarene. Additionally, we note that the initially dominant anti-aryl conformer appears to be a kinetic product of the oxidation step of the synthesis with Tl(CF3CO2)3. Variable-temperature NMR studies in the absence of salt show a stable ∼4:1 ratio of anti to syn conformer, while the compound, as initially prepared in solution, exhibits a ratio of >50:1.

Conformational isomerism

Moiety

Calixarene

Conformational change

Proton NMR

10.1021/ja963601s

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Citations (29)

Reducing Burst Loss Probability of Service Differentiated Optical Burst-Switched Networks

P. Amruta Reddy Arvind Nagarajan Krishnamurthy Ramanujam Srinivas Talabathula

This paper will extend the existing absolute quality-of-service (QoS) scheme to a service-differentiated Optical Burst-Switched Network. We will show that the burst loss probability of our service-differentiated model will decrease compared to the previous model [3].

Optical burst switching

10.1364/photonics.2012.wpo.31

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Citations (2)

Advanced monitoring and on-line health diagnosis of single-phase transformers

P. Amruta Reddy Anil Kumar Sao Bharat Singh Rajpurohit

Transformers range in size from a few kVA to several hundred MVA are one of the most critical components of power system with with replacement costs around millions of dollars for power transformers. A sudden in-service failure of a transformer not only results in substantial economic losses but also can result in death of utility personnel apart from the environmental damages caused and grid instability induced. The condition assessment and life estimation of a transformer is an important part of reliable power system operation. The equivalent parameters of a transformer are not affected by external faults and change only in the presence of internal abberations making them suitable for internal condition assessment of transformers. Presently, there is no accurate measurement method for the transformer winding parameters and generally require the transformer to be disconnected from the power system. A new simple algorithm for extracting transformer winding parameters which can be implemented online is presented in this paper. This method doesn't require the transformer to be disconnected from the power grid. The primary and secondary currents and voltages are taken as inputs and winding parameters are obtained by solving the equivalent circuit equations in real time continuously which allows for interpretation and detection of faults in real-time. The proposed method has been tested and validated by simulations. Different cases of parameter variations and their possible interpretations are discussed in order to detect any incipient faults or anomalies in an in-service transformer which serve as advance alarms.

Energy efficient transformer

Power grid

Delta-wye transformer

10.1109/icpace.2015.7274964

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Citations (3)

Synthesis and Anticonvulsant Activities of 3,3-Dialkyl- and 3-Alkyl-3-benzyl-2-piperidinones (δ-Valerolactams) and Hexahydro-2H-azepin-2-ones (ε-Caprolactams)

Journal of Medicinal Chemistry (1997)

P. Amruta Reddy Karen E. Woodward Sarah M. McIlheran B. C. H. HSIANG Tammy Latifi

A series of 3-substituted 2-piperidinone (δ-valerolactam) and hexahydro-2H-azepin-2-one (ε-caprolactam) derivatives were prepared and evaluated as anticonvulsants in mice. In the 2-piperidinone series, 3,3-diethyl compound 7b is the most effective anticonvulsant against pentylenetetrazole-induced seizures (ED50, 37 mg/kg; PI (TD50/ED50), 4.46), and 3-benzyl compound 4c (ED50, 41 mg/kg; PI, 7.05) is the most effective anticonvulsant against seizures induced by maximal electroshock. By contrast, none of the ε-caprolactams tested had anticonvulsant effects below doses causing rotorod toxicity. log P values were correlated with neurotoxicity and [35S]TBPS displacement, but not with anticonvulsant activity. Electrophysiological evaluations of selected compounds from each series indicated that both the δ-valerolactams and ε-caprolactams potentiated GABA-mediated chloride currents in rat hippocampal neurons.

ED50

Convulsants

Neurotoxicity

10.1021/jm960561u

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Citations (43)

ChemInform Abstract: A Facile Synthesis of 2,3-Dihydroselenolo(3,2-c)- and 2,3-Dihydrotellurolo(3,2-c)quinolines.

ChemInform (1992)

T. Raja G. MUTHUVIJAYAN P. Amruta Reddy Joghee Gowder Lakshmanan R. Divakar

10.1002/chin.199228225

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Vitamin D Supplementation during Pregnancy.

A Sachan CV Harinarayan D Gunasekhar P Sreevani B Bhargavi

10.1210/endo-meetings.2010.part1.p4.p1-176

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Citations (6)