M Coulibaly

BG University Hospital Bergmannsheil Bochum

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Thomas A. Schildhauer

BG University Hospital Bergmannsheil Bochum

Matthias Königshausen

BG University Hospital Bergmannsheil Bochum

E. Bissagnéné

University Hospital Medical Center at Treichville

A. Kadio

Université Jean Lorougnon Guédé

Oliver J. Liakopoulos

Kerckhoff Klinik

A Assoumou

Centre Hospitalier Universitaire de Cocody

D. Seybold

BG University Hospital Bergmannsheil Bochum

Christian Sellin

Klinikum Fulda

E Aoussi

University of Lomé

Friedrich A. Schoendube

University of Göttingen

Cooperative Institutions

University of Bamako

Mali-Folkecenter

Université des Sciences, des Techniques et des Technologies de Bamako

Université Félix Houphouët-Boigny

University of Göttingen

Inserm

University Hospital Medical Center at Treichville

BG University Hospital Bergmannsheil Bochum

Ruhr University Bochum

Centre Hospitalier Universitaire de Cocody

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Étude des déterminants de la déperdition des personnes vivant avec le sous traitement ARV suivies au niveau des structures sanitaires au Sénégal

Revue d Épidémiologie et de Santé Publique (2019)

Atoumane Faye Farokh Niass Abdourahmane Diallo M Coulibaly Cheikh Tidiane Ndour

10.1016/j.respe.2019.03.048

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Diplopie Révélatrice de Cryptococcose Neuroméningée chez un Sujet Immunocompétent au VIH

Dramane Samaké M Coulibaly I Konaté Kéita D Goïta

RESUMELa cryptococcose neuromeningee est une infection fongique frequente chez les patients immunodeprimes au VIH. Sa survenue sur terrain immunocompetent au VIH doit faire rechercher systematiquement d’autres facteurs favorisants. Nous rapportons un cas de cryptococcose neuromeningee chez une patiente de 32 ans immunocompetente au VIH, sans aucun facteur d’immunodepression connu et sans antecedents medicaux notables qui a presente un tableau de meningo-encephalite subaigu et des troubles de la vision a type de diplopie. Le test au VIH etait negatif avec un taux de CD4 egal a 1367 cellules/mm3.La culture bacterienne du liquide cerebrospinal etait egalement sterile. Les virus responsables d’infection meningee n’ont pas ete recherches a cause de non disponibilite de ces analyses. L’evolution ete favorable sous fluconazole pendant la phase d’attaque du traitement puis les symptomes ont repris en debut de la phase d’entretien. Elle est decedee le 16eme jour du traitement. Le contexte de meningite bacterienne ou virale ne doit pas faire occulter la possibilite d’une meningite a cryptocoque quelque soit l’etat immunitaireABSTRACTNeuromeningeal cryptococcosis is a common fungal infection in HIV-immunocompromised patients. Its occurrence on immunocompetent patients to HIV should prompt to seek other predisposing factors. We report a case of neuromeningeal cryptococcosis in an immunocompetent 32-year-old female patient, without any known immunosuppressive factor and without a notable medical history. She presented with subacute meningoencephalitis and diplopia-type vision disorder syndrome. HIV serology was negative and the CD4 count was 1367 cells / mm3. The bacterial culture of the cerebrospinal fluid was sterile. Diagnostic tests for other virus responsible for meningeal infection were unavailable. Clinical course during the early days of initiation treatment with fluconazole was good. But, the symptoms and signs relapsed at the beginning of the maintenance phase. She died on the 16th day. A clinical picture of bacterial or viral meningitis should not overshadow the possibility of cryptococcal meningitis whatever the immune status.

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LEADERSHIP OF THE EVANGELICAL CHURCHES IN THE FIGHT AGAINST HIV/AIDS: THE CASE OF SUD-COMOE IN CÔTE D'IVOIRE

M Coulibaly

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P2150 Right-ventricular pressure load in pigs: progressive loss of regional myocardial function without ischaemia

European Heart Journal (2003)

M Coulibaly

Ventricular Function

Myocardial ischaemia

10.1016/s0195-668x(03)95144-x

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[Problems produced by the use of antitubercular agents in a reference service for HIV/AIDS in Abidjan (Côte d'Ivoire)].

PubMed (1999)

A. Kakou S P Eholié Bolong Yao M Coulibaly Eboi Ehui

This study reports on the experience using antituberculosis drugs in a HIV/AIDS reference service in Abidjan during a 64 month period. Prevalence of tuberculosis is 1.9% out of a total of 23,957 patients. The annual incidence rate increased slowly from 0.9% in 1990 to 3.5% in 1995. Seropositivity to HIV is 90.8%. Predominant locations of tuberculosis are pulmonary (60.3%), extrapulmonary (19.7%) and multifocal or disseminated (20%). The average period of diagnosis (9.9 days) and average duration of antituberculosis treatment in hospital (11.8 days) are similar whatever the serological status and the location of the infection may be. However, the mortality rate is more important in HIV positive patients (39.7%) than in HIV negative (17.6%) p = 0.01. The decision to treat is taken by infectiologists only in 88% of the cases, by pneumologists only in 2.5%, and both by infectiologists and pneumologists in 9.5%. Side-effects due to antituberculosis drugs were noticed in 19 patients leading to an interruption of the treatment in 10 cases. The authors recommend that health personnel be trained for the management of tuberculosis.

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Progressive right ventricular failure is not explained by myocardial ischemia in a pig model of right ventricular pressure overload

European Journal of Cardio-Thoracic Surgery (2008)

Jan D. Schmitto Hilmar Doerge Heiner Post M Coulibaly Christian Sellin

Background: Current concepts of acute pulmonary embolism suggest that right ventricular (RV) dilatation and failure are the consequence of pressure overload-induced RV hypoperfusion and ischemia. Methods: Sixteen human-sized hybrid pigs were instrumented for the measurement of RV and aortic pressure, aortic and right coronary artery blood flow (RCA BF), RV oxygen consumption (RV MVO2) and RV free wall segment length. The pulmonary artery was constricted (PAC) to increase RV peak pressure acutely 2.5-fold (from 27 ± 2 to 64 ± 3 mmHg, n = 9), and the constriction was maintained for 6 h. Results: At 10 min after PAC, a RV work index (RVWI, RV pressure-segment length loops) was increased 2.3-fold, indicating an initial RV adaptation to increased afterload. At 1 h, 3 h and 6 h after PAC, however, RVWI decreased progressively towards control levels, while RCA BF and RV MVO2 continued to increase. The arterial-coronary venous pH difference did not increase throughout the protocol. Arterial troponin T concentration increased from 0.08 ± 0.03 to 0.80 ± 0.20 ng/ml at 6 h after PAC. None of the parameters changed in control animals (n = 7). Conclusion: We conclude that in our model RV failure during PAC develops in spite of increased coronary blood flow and MVO2. Thus, mechanisms different from ischemia may contribute to progressive RV failure after pulmonary embolism.

Pressure overload

Afterload

Ventricular pressure

Aortic pressure

Constriction

10.1016/j.ejcts.2008.09.010

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Un nouveau cas de néphropathie tubulo-interstitielle chronique induite par la glucosamine et revue de la littérature

Néphrologie & Thérapeutique (2015)

SM Gueye M. Saint Cricq M Coulibaly N. Goumri Céline Guilbeau‐Frugier

10.1016/j.nephro.2015.07.400

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Right ventricular pressure load in pigs: Progressive loss of contractility W/O ischemia and downregulation of Ca2+ handling proteins

The Journal of Heart and Lung Transplantation (2005)

M Coulibaly Hilmar Doerge C. Muehlfeld Friedrich A. Schoendube

Contractility

Ventricular pressure

10.1016/j.healun.2004.12.020

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Fine particulate matter pollution in African urban area: An urgent need for action

International Journal of Advanced Research and Development (2018)

Attoh Touré H M Coulibaly René Kouao Issaka Tiembré A. Konaré

Particulate Pollution

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[Assessment of a programme of prevention of mother-to-child transmission of HIV in Abidjan, Ivory Coast (1999-20002)].

PubMed (2006)

M Coulibaly Noba Rey Jl Philippe Msellati René Ekpini

The purpose of this article is to report the results of a programme for prevention of mother-to-child transmission (PMCT) of HIV conducted from 1999 to 2002 by the PNLS in Abidjan, Ivory Coast. This programme was supported by grants from the Fonds de solidarité international (FSTI) and the Glaxo Smith Kline (GSK) Foundation. After pre- and posttest counselling, pregnant women from 4 PMI centres underwent screening for HIV. Seropositive women were offered short course AZT and the possibility of financial assistance for breast-feeding. All programme activities were carried out in close cooperation with association members. A total of 22466 tests were given and 18116 women returned for results. Among the 1829 seropositive women to whom PMCT intervention was proposed, 667 received short course AZT. The rate of transmission at 18 months was 162%. In addition 69 mothers and 28 children eligible for ARV therapy benefited from tritherapy. Limiting factors, at each phase, and efficacy of intervention were analyzed.

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