Little has been written in recent years to update the pediatric perfusion literature. This paper is a review of the perfusion techniques we use with 200 children a year in Denver and we believe it is a reflection of the state-of-the-art. We will discuss equipment selection (including a method of streamlining inventory), circuit prime, anticoagulation, temperature control, blood flow, myocardial protection, blood conservation, patient safety, and cost containment. Deep hypothermia and circulatory arrest are used with most children under 8 Kg. and acid-base status is managed to maintain respiratory alkalosis with the help of on-line monitoring. Pulsatile flow is used on all patients and hollow fiber membrane oxygenators and blood cardioplegia are used on most. The choice of oxygenator size, and subsequent priming volume, is influenced by the decrease in gas exchange efficiency (− 20%) at this altitude and must be understood in that context. All other information is appropriate at any altitude and will be helpful to a team who does few pediatric cases or is starting up a program.
We describe a case of lumbosacral plexopathy caused by an isolated aneurysm of the common iliac artery. The patient presented with worsening low back pain, progressive numbness and weakness of the right leg in the L2-L4 distribution. This had previously been diagnosed as sciatica. A CT scan showed an aneurysm of the right common iliac artery which measured 8 cm in diameter. Despite being listed for emergency endovascular stenting, the aneurysm ruptured and the patient died. It is important to distinguish a lumbosacral plexopathy from sciatica and to bear in mind its treatable causes which include aneurysms of the common and internal iliac arteries.
Thirty cadaver necks were dissected to determine the course of the accessory nerve distal to the posterior triangle. The nerve was found to have a constant course on the deep surface of the trapezius muscle. This has clinical implications for surgery in the region.
Three clusters of an unusual syndrome in premature infants were investigated in three intensive care nurseries in 1984. A retrospective cohort study of 68 infants weighing less than or equal to 1,250 g at birth and surviving at least 72 hours revealed that in 13 infants ascites developed and in four at least two of the following abnormal laboratory values were found within a seven-day period: serum direct bilirubin greater than or equal to 2 mg/dL, blood urea nitrogen greater than or equal to 40 mg/dL or serum creatinine greater than or equal to 2 mg/dL, and platelet count less than or equal to 60,000/microL. All cases occurred after the introduction and use of intravenous E-Ferol, a vitamin E preparation that was new on the market when the clusters were reported. All 17 case infants but only 23 of 51 (45%) noncase infants received E-Ferol (P less than .0001). Case and noncase infants were similar with respect to other complications and to receipt of medications and parenteral nutrition. A dose-response relationship was found; cases occurred in infants receiving E-Ferol dosages of greater than 20 U/kg/d. Case infants who had higher daily doses of E-Ferol had a shorter latency. No new cases were reported after use of E-Ferol was stopped. Results of these investigations led to a nationwide recall of intravenous E-Ferol.
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