Jan C. den Hollander

Erasmus University Rotterdam

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Arnold P. Oranje

Erasmus MC

Rogier Heide

Erasmus University Rotterdam

Dirk Van Gysel

Vrije Universiteit Brussel

Auke Beishuizen

Princess Máxima Center

Suzanne G.M.A. Pasmans

Erasmus MC

Flora B. de Waard‐van der Spek

Sint Franciscus Gasthuis

Talia Kakourou

National and Kapodistrian University of Athens

Marieke M.B. Seyger

Radboud University Nijmegen

Eric M. van der Snoek

Central Military Hospital

Esther Zuidema

Erasmus MC - Sophia Children’s Hospital

Cooperative Institutions

Erasmus University Rotterdam

130

Erasmus MC

123

Erasmus MC - Sophia Children’s Hospital

Rotterdam University of Applied Sciences

Boston Children's Hospital

University Medical Center

University of Amsterdam

Leiden University

Radboud University Nijmegen

University of Groningen

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[Anorectal malignancies and dysplasia in HIV-positive men who have sex with men].

PubMed (2005)

Eric M. van der Snoek Marc van der Valk W. R. Schouten Jan C. den Hollander W I van der Meijden

Since the HIV epidemic, the incidence ofanorectal (pre)malignancies in men who have sex with men (MSM) is increasing. The incidence is likely to increase further in the coming years, given that HIV-positive MSM are living longer thanks to powerful antiretroviral treatment. Persistent human papillomavirus (HPV) infection is a major risk factor for the development of anal (pre)malignancies. Less is known about the natural history of anal intraepithelial neoplasia (AIN). Screening in HIV-positive and HIV-negative MSM for anorectal malignancies or dysplasia is cost-effective if the incidence is sufficiently high. Treatment options range from watchful waiting for asymptomatic grade-1 AIN to excision or radio(chemo)therapy for anorectal carcinoma. HPV vaccines are in development. Especially in HIV-positive MSM with anorectal complaints or genital warts in their medical history, one should consider these malignancies.

Watchful waiting

Genital warts

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Citations (2)

COL4A2 mutation associated with familial porencephaly and small-vessel disease

European Journal of Human Genetics (2012)

Elly Verbeek Marije Meuwissen Frans W. Verheijen Paul Govaert Daniel J. Licht

Porencephaly

Penetrance

10.1038/ejhg.2012.20

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Citations (100)

Congenital Polyp of the Prostatic Urethra in Childhood

Urologia Internationalis (1985)

E. Bruijnes J.G. de Wall R. Scholtmeijer Jan C. den Hollander

Congenital polyps of the prostatic urethra are supposed to be rare benign hamartomatous protrusions of the urethral wall in infants. The core contains predominantly connective tissue with cellular constituents of the lamina propria, but also smooth muscle cells, islets of glandular cells and even nerve tissue have been described. The core is lined by transitional epithelium, but in several cases squamous metaplasia has been reported. Because the polyp may act as a ball valve, mainly obstructive symptoms are presented. Suprapubic approach is generally recommended resecting a polyp; however, smaller lesions are accessible to transurethral resection. Three cases presenting different symptoms are reported. In 1 patient the polyp contained keratinized squamous epithelium.

Lamina propria

Squamous metaplasia

Transitional epithelium

Prostatic urethra

10.1159/000281102

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Citations (8)

Rhabdoid Tumor Mimicking Hemangioma

Pediatric Dermatology (2010)

Yvette J. Assen Gerard C. Madern Peter C. J. de Laat Jan C. den Hollander Arnold P. Oranje

Abstract: We report a young boy with a malignant tumor, which remained unrecognized for 8 months because it was assumed to be a hemangioma. The presentation of a rhabdoid tumor mimicking hemangioma is very rare. It was reported only on two earlier occasions. Rhabdoid tumors are one of the most aggressive types of malignancies encountered in pediatric oncology. It is important to recognize that a fast growing vascular lesion in a child will often be a hemangioma, but could also be an aggressive tumor.

Infantile hemangioma

Vascular Tumors

Pediatric Oncology

Presentation (obstetrics)

10.1111/j.1525-1470.2010.01248.x

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Citations (6)

Acquired Scrotal Lymphangioma Successfully Treated Using Carbon Dioxide Laser Ablation

Dermatologic Surgery (2011)

E Lanjouw Kees-Peter de Roos Jan C. den Hollander Errol P. Prens

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Subscribe Register Login Articles & Issues Current IssuePrevious IssuesPublished Ahead-of-PrintSpecial Issues Collections Advancement FlapCartilage GraphCompsite GraphEar ReconstructionEyelid ReconstructionFull Thickness Skin GraphInterpolation FlapLip ReconstructionNasal ALANasal ReconstructionNasal Tip - SidewallPull Through FlapRotation FlapSkin Cancer AwarenessSoft TriangleTransposistion Flap VideosPodcastFor Authors Submit a ManuscriptInformation for AuthorsLanguage Editing ServicesAuthor Permissions Journal Info About the JournalEditorial BoardAbout the societyAdvertisingSubscription ServicesReprintsOpen AccessRights and PermissionsNZSCM Member Info All Articles Images Videos Podcasts Blogs Advanced Search

Logo (programming language)

10.1111/j.1524-4725.2011.01914.x

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Citations (8)

Prenatal testicular torsion: diagnosis and natural course. An ultrasonographic study

European Radiology (2003)

Jan Willem van der Sluijs Jan C. den Hollander Maarten H. Lequin Rien M. Nijman Simon G. F. Robben

Hydrocele

Tunica vaginalis

Tunica albuginea (penis)

Orchitis

Epididymitis

10.1007/s00330-003-2019-0

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Citations (43)

Separation of the Umbilical Cord – Histological Findings

Neonatology (1990)

Anne Marie Oudesluys‐Murphy Jan C. den Hollander

Even though the separation of the umbilical cord receives a great deal of interest, the process of cord separation has not been reported in the literature. A histological study of the umbilical area was carried out on 25 neonates who died within 7 days of birth (mean age at death 3 days). The umbilical cord itself became dried and mummified. Polymorphonuclear leucocytes infiltrated the areas between the mummifying cord stump and the vital tissues of the abdominal wall, forming a demarcation zone. No other leucocytes were present, and no bacteria were seen in any of the preparations studied.

10.1159/000243231

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Citations (15)

Autoimmune Lymphoproliferative Syndrome (ALPS) in a Child from Consanguineous Parents: A Dominant or Recessive Disease?

Pediatric Research (2000)

Mirjam van der Burg Ronald de Groot W M Comans-Bitter Jan C. den Hollander Herbert Hooijkaas

Autoimmune lymphoproliferative syndrome

Fas ligand

Heterozygote advantage

Lymphoproliferative Disorders

10.1203/00006450-200003000-00009

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Citations (61)

Small-Cell Undifferentiated (Neuroendocrine) Carcinoma of the Cecum in a Child with Common Variable Immunodeficiency

Journal of Pediatric Hematology/Oncology (1993)

Niels C. de Bruin Ronald de Groot Jan C. den Hollander Stefan I. Agoston Jacques J. M. van Dongen

Purpose Patients with primary or secondary immunodeficiencies are known to be at increased risk for the development of malignancies, predominantly of lymphoreticular origin. Patients and Methods We here describe a patient with infant-onset hypogammaglobulinemia due to a common variable immunodeficiency. At the age of 16 a small-cell undifferentiated (neuroendocrine) carcinoma of the cecum (SCUNC) was diagnosed. Results Neurohormonal analysis showed normal values. Conclusions: To our knowledge this is the first report in childhood of SCUNC of the gastrointestinal tract, which has also previously not been associated with primary immunodeficiency.

Hypogammaglobulinemia

Cecum

Common Variable Immunodeficiency

Primary Immunodeficiency

10.1097/00043426-199305000-00016

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Citations (16)

Author Index vol. 219, 2009

Dermatology (2009)

N. Irla N. Yawalkar Claudia M. Witt Benno Brinkhaus Daniel Pach

10.1159/000263812

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Citations (0)