In order to study the role of human papillomavirus (HPV) in genital cancer, we attempt to determine the presence of HPV in tumors of the genital tract. In the current study, we have examined 35 histologically diagnosed cases of vulvar lesions in attempts to compare the sensitivities of various methods of detecting HPV. All but 7 vulvar lesions contained HPV DNA by Southern blot DNA hybridization. Detectability of HPV by immunocytochemistry and koilocytosis significantly declined as compared to DNA hybridization. The detection of HPV DNA by in situ hybridization is discussed.

Koilocyte

Southern blot

DNA–DNA hybridization

Genital tract

Sex organ

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ChemInform Abstract: STUDIES ON PEPTIDES. 92. TOTAL SYNTHESIS OF BOVINE PANCREATIC RIBONUCLEASE A. . PART 5. SYNTHESIS OF THE PROTECTED S‐PROTEIN (POSITIONS 21‐124) AND THE PROTECTED S‐PEPTIDE (POSITIONS 1‐20)

Chemischer Informationsdienst (1981)

Noriyuki Fujii H. YAJIMA

Abstract Der weitere Aufbau zur Titelsequenz (II) (S‐Protein) durch schrittweise Kondensationen (Azidmethode) mit den Fragmenten (III)‐(VIII) [Kupp1ungsausb.

Bovine pancreatic ribonuclease

10.1002/chin.198123317

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ChemInform Abstract: SYNTHESIS OF THE DOCOSAPEPTIDE CORRESPONDING TO THE AMINO ACID SEQUENCE OF OSTRICH‐TYPE CORTICOTROPIN‐LIKE INTERMEDIATE LOBE PEPTIDE (CLIP)

Chemischer Informationsdienst (1981)

KOICHI YASUMURA Kazuyo Okamoto SHINICHI SHIMAMURA H. YAJIMA

Sequence (biology)

10.1002/chin.198139360

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[Synthesis and the future of peptide hormones].