John F. Templeton

University of Manitoba

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Vinay Kumar

Penn State Milton S. Hershey Medical Center

Frank S. LaBella

University of Manitoba

Kirk Marat

University of Manitoba

C. W. Wie

University of Manitoba

Yangzhi Ling

Peking University

Talal H. Zeglam

University of Tripoli

Helena Majgier-Báranowska

Microbiotix (United States)

K. MARAT

University of Manitoba

Weiyang Lin

Cummins (United States)

D. Böse

Regional Cancer Center, Thiruvananthapuram

Cooperative Institutions

University of Manitoba

Imperial College London

National Research Council Canada

University College London

Medical Council of Canada

Baylor College of Medicine

Analytisches Laboratorium

Centre National de la Recherche Scientifique

University of London

University of Sydney

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ChemInform Abstract: SYNTHESIS OF SOME A-RING STEROIDAL CYCLOPROPANOLS

Chemischer Informationsdienst (1975)

John F. Templeton C. W. Wie

Behandlung des Androstanons (I) mit Brom liefert das Dibromderivat (II), das zu den Epimeren (IIIa) und (IIIb) (Trennung durch fraktionierte Kristallisation) reduziert wird.

10.1002/chin.197539377

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Effect of lipophilic counter-ions on membrane diffusion of benzydamine

European Journal of Pharmaceutical Sciences (2005)

Vikram Sarveiya John F. Templeton Heather A. E. Benson

Penetration (warfare)

10.1016/j.ejps.2005.04.013

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Citations (31)

Synthesis of 3β,14-dihydroxy-5β,14β-pregnan-20-one C-3 derivatives: ozonolysis of digitoxin and digitoxigenin and their derivatives followed by zinc–acetic acid reduction to the C-21 methyl ketone

Journal of the Chemical Society. Perkin transactions I/Journal of the Chemical Society. Perkin transactions. I (1991)

John F. Templeton Yangzhi Ling Jin Jichun Mark A. Boehmer Talal H. Zeglam

Ozonolysis of digitoxin, digitoxin tetraacetate, digitoxin tetrakis-(2,2,2-trichloroethyl carbonate), digitoxigenin, digitoxigenin acetate, digitoxigenin hemisuccinate and digitoxigenin 2,2,2-trichloroethyl carbonate followed by treatment with excess of zinc in acetic acid gave either the corresponding 21-hydroxy ester after 5 min or the 21-methyl ketone after 20 h. This procedure is more efficient than methods previously reported for the conversion of the α,β-unsaturated γ-lactone into an acetyl group and is applicable to the cardiac glycosides directly to give 14β-hydroxypregnan-20-one derivatives. Acidic hydrolysis of 14,21-dihydroxy-and 14-hydroxy-3β-tris(digitoxosyloxy)-5β,14β-pregnan-20-one is reported. Structures are based on 1H and 12C NMR assignments.

Digitoxigenin

Digitoxin

Butenolide

Trifluoroacetic acid

10.1039/p19910000823

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Citations (11)

Metabolism of 17α-methyl-5α-dihydrotestosterone in the rabbit

Steroids (1982)

John F. Templeton Jackson Chung-Ja Choi K. L. Seaman

Androstane

Hydroxylation

Triol

Epimer

Dihydrotestosterone

10.1016/0039-128x(82)90051-4

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Citations (8)

ChemInform Abstract: Progesterone Derivatives That Bind to the Digitalis Receptor: Synthesis of 14β‐Hydroxyprogesterone. A Novel Steroid with Positive Inotropic Activity.

ChemInform (1988)

John F. Templeton Vinay Kumar Donald Coté D. Böse D. Elliott

10.1002/chin.198807331

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ChemInform Abstract: Synthesis of 3β,14‐Dihydroxy‐5β,14β‐pregnan‐20‐one C‐3 Derivatives: Ozonolysis of Digitoxin and Digitoxigenin and Their Derivatives Followed by Zinc‐Acetic Acid Reduction to the C‐21 Methyl Ketone.

ChemInform (1991)

John F. Templeton Yong Ling Jin Jichun Mark A. Boehmer Talal H. Zeglam

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.199128210

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Global Investing: The Templeton Way

Norman Berryessa Eric Kirzner John F. Templeton

Readers will learn in this enlightening book how to apply the investment techniques of John Templeton, the pioneer of global investing. Provides pointers on how to protect money by pursuing a dynamic yet balanced program of global investing.

Investment

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Citations (4)

Reductive coupling of carbon monoxide to C sub 2 products

John F. Templeton

Progress since the initiation of this two year award on May 1, 1988, has been divided into two areas for reporting purposes. We have been working on ideas described in the proposal submitted two years ago, and simultaneously we initiated chemistry in a distinct area in order to provide a springboard for the current proposal. Efforts directed toward reductive coupling of carbon monoxide have continued to focus on carbyne species as the central figure in coupling reactions. At the same time we have attempted to prepare intermediate oxidation state metal imido complexes with an eye to synthetic applications of nitrene transfer reagents. The results of carbyne chemistry, electrophilic addition reactions of anionic carbonyl and isonitrile complexes, and carbyne-carbonyl coupling reactions will be presented in this progress report, while the work with nitrene complexes will be included as preliminary results in the text of the accompanying proposal. The description of published work will be brief in this report; greater detail will be provided for unpublished material.

Carbyne

Nitrene

Coupling reaction

10.2172/6945205

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Effect of bufalin and pregnanes on vasoreactivity of human resistance arteries

Biochemical and Biophysical Research Communications (1992)

Robin G. Woolfson J. E. Graves Frank S. LaBella John F. Templeton Lucilla Poston

Bufalin

10.1016/s0006-291x(05)80767-3

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